BACK TO MAIN Study Title Characterization Study of PFOS, Primary Standard - Test Control Reference #TCR-00017-046 PHASE:SOLUBILITY OF PFOS IN WATER Data Requirement 40 CFR 160.105(b) Author Mark E.

FORM 10620-PWO BACK TO MAIN CC: LAB REQUEST BOOK - 42-5W File: Water and Wastewater REQUEST FOR LABORATORY WORK Lab RequestNo* 1231 TO: ENVl RONMENTAL ENGINEERING LABORATORY - BUILDING 53-6N equestor -&dE Name: Request Date Project No.

.J SRPT T-76G( MIN 3141022208 PERFLUOROOCTANESESULFONYLFLUORIDE OSF') T 7 b t l .a BACTERIAL REVERSE MUTATION TEST Sponsor 3M Center 3M Corporate Toxicology Building 220-2E-02 St Paul MN 55133-3220 USA Research Laboratory HuntingdonLife SciencesLtd.

February 11,2005 Dr.

AR226-1894 Reproductive Effects of C8 James Dahigren, MD Pamela Anderson-Mahoney, PhD November 2004 Reproductive Hormones Male C8 Workers Increased PFOA Levels Lower Testosterone Prolactin Higher Estrogen Prolactin if high alcohol intake Health Study in Residents Near a Large C8 Source Methods 301 females and 296 males with documented PFOA--Exposu re ~0.05 ug/L in drinking water standardized questionnaire SEER prevalence data were used for comparison Demographics for Residential Study Participants Age Category 20--34 35--44 45--54 55--64 65-8() Gender Male Female Race/Ethnicity White African Others American Education Level Less than 9~grade 9-- 1 l'~'grade - til

Ae226-1918 --c A CHARLES RIVER COMPANY PATHOLOGY PEER REVIEWREPORT ZBWEEK CAPSULETOXICITY STUDYWITHAMMONIUM PERFLUGROOCTANGATE Co(vAaPnFcOe)SItN uCyYNNOuMmbOeLrG6U3S26M.O2N9KEYS osuEcTvE E Aeicusecopairetetsenvtnvdofatnhnatceu hesoosmosaflonHg(d0oSsTe na il1,57s5e0lecwtoesdLpornatoomtond.isTh,e iyofsrl OT ars R724 MATERIALS AND METHODS Toe sic faom aae ssaesafcoo tmsal(aOnanarlssetafvtdooOyGTrovRu)po4w, streleoctemd nGreoups1 eanirmala, anaaris re0 spuosser SR) SE Wt Ag nn 5, FEED the determination of the cause of moribundity for the Group 4 animal (105724).

AR226-1988 Ig^^^^^.^.

AR226-2076 3<]K?

TestResults AR226-2118 fle:///C|/WlNDOWS/TEMP7C-8 Per 1-1-70 thro 8-12-81.htm 1 of 9 ''^iiiy Test Results SampiB Data Range Concentration Range Action Level Industrial Hygiene 1/1/70 8/12/81 100% Sample Dt Sample # Duration Type Employee Name Pers 8TO: LOG: 04 POWER & SERVICES 074 INCINERATOR AREA - GENERAL 4/13/81 32328 P none Chemical Cone Unit Percent G-8 0.0012 PPM 4/15/81 32329 none C-8 0.0008 PPM 0.0% BTO: LOG : 08 TEFLON 802 P/S - FINE POWDER DRYER OPERATOR (08PI) 10/23/79 33473 P "one 10/28/79 33474 P "one 10/30/79 33475 P, none 3/18/80 33476 3/20/80 33477 none 3/21/80 33478 3/21/80 33479 none 3/22/80 33480 3/22/80 33481 3/23/80 33482 3/25/80 33483 3/26/80 33484 C-8 0.001 PPM 0.0% C-8 0.0009 PPM 0,0% C-8 <0.0001 PPM 0.0% C-8 0.0009 PPM 0,0% C-8 0.0009 PPM 0.0% C-8 0.0023 PPM 0.0% C-8 0.0016 PPM 0.0% C-8 0.0025 PPM 0.0% ;> C-8 0,0026 PPM 0 0.0% ^ K> C-8 0.0015 PPM Is) ^ 0.0% C-8 0.0011 PPM 0.0% C-8 0.0006 PPM 8/9/2001 3:49 PM EID139466 TestResutts 3/26/80 33485 P 3/27/80 33486 P 3/27/80 33487 P 3/28/80 33488 P 9/3/80 33489 P 9/4/BO 33490 P 9/4/80 33491 P 9/4/80 33492 P 9/5/80 33493 P 9/6/80 33494 P 9/7/80 33495 P 9/8/80 33496 P 9/9/80 33497 P 9/10/80 33498 6/13/81 33493 Thursday, August OS, 2001 3:17:45 PM file:///C|/WINDOWS/TEMP/C-8 Per 1-1-70 Ihru 8-l2.81.htm none none none none none none none none none none none none none C-8 C-8 C-8 08 C-8 C-8 C-8 C.8 C-8 C-8 C-8 C-8 C-8 C-8 C-8 0,0004 PPM 0.001 PPM 0.0022 PPM 0.0001 PPM 0.0003 PPM 0-0004 PPM 0.0006 PPM 0.0004 PPM 0.0001 PPM 0,0002 PPM 0.0002 PPM 0.0001 PPM <0.0001 PPM 0.0001 PPM 0.001 PPM 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% Page!

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AR226-2398 \ INTEROFFICE MEMORANDUM Dates Promt Dept: Tel No s SO-Jan-lseS OlslSprn ANTHONY J.

\ ^ A^T r t/t AR226-2413 ..aernm OT;" 302 B9S 4B2e Fax ^nsmittal Memo i> CCBW cttA-wy111- laate* A ^ -ba- - - -- ^ CiXllAW^I Ufil -^ ^^1^^ ^ ^2^5 DU FONT POLYMERS 001 7(72 "'^ f<M ^^{f^'^^^ (3.

AR226-2457 WWK PC-143 RESULTS DATESMPL SRCNAME 22-Nov-91 LOWER POND 22.Nov.91 UPPER POND 27-Deo-91 LOWER POND .27-066-91 UPPER POND 15.Mar-94 LMW.2A 15-Mar-94.LMW-5B 15-Mar-94 LOWER POND 15-Mar-94 STREAM MN RD 15-Mar-94 UPPER POND 20.S6p.94 LMW-2A 20-8ep-94 UMW-5B 20^ep.94 LOWER POND 20-Sep-94 STREAM MM RD 2-Apr-@6 001 POND OUTLET 2-Apr-9@ 002 POND OUTLET 2-Apr-96 003 POND OUTLET 2-A(M'-96 MW80 2-Ap-96 OUTFALL 004 2"Apr-@6 OUTFALL 005 2.Apr-96 STREAM 1 2-Apr-96 STREAM 2 2-Apr-96 WILL 331 2-Apr-9@ WELL 338 9-Apr"@6 DWN8TREAM 9-Apr-9Q OUn-ET 9-Apr-96 PROPBOUND 10-Apr-96 FBLK IO.Apr-96 MW-12 1t>.Apr.@6 MW"6 10"Apr-96 MW12A 10-Apr-96 MW13A 10-Apr-96 MW13A DATIESMPL SRCNAME 10.Apr.96 10-Apr-96 H-Apr-96 H-Apr-96 11.Apr.96 H-Apr-96 H-Apr-96 17-ApP.96 MW14 MW6A FBLK MW-4 MW-6 MW-9 WEST WELL FBLK 17-Apr-96 LMW-1 17-Apr-96 LMW-2A 17-Apr-96 LMW-7 17-Apr-96 LMW.8 ANALYTE R8LTMOD RESULT PQL UNIT PC'143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 PC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 PC.143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 PC-143 FC-143 FC-143 FC-143 FC-143 1 0,79 1.3 4.1 260 1200 730 0.6 4400 270 530 2200 0.9 61 72 20 < 0.1 13 39 7.2 14 0.82 0.48 25 86 9.9 < 0,1 < 0.1 0.&7 < 0.1 11 8,2 MG/L MG/L MG/L MG/L ug/1 ug/l ug/1 U9/1 ug/1 ug/1 ug/1 ug/l ug/ 4 UG/L 4 UG/L 2UQ/L 0.1 UG/L 1 UO/L 2.5 UG/L 0.5 UG/L 1 U6/L 0.1 UG/L 0.1 U0/L 3 UG/L 20 UG/L 0.5 UG/L 0.1 UQ/L 0.1 UG/L 0.1 UG/L 0.1 UG/L 1 UO/L 1 UG/L ANALYTE RSLTMOD) RESULT PQL UNIT FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 PC-143 FC-143 PC-143 FC-143 FC-143 < 0.1 0.19 < 0.1 39 15 0.14 3.7 < 0.1 1700 460 15 2200 0.1 UG/L 0.1 UG/L 0.1 UG/L 5 UG/L 2 UG/L 0.1 UG/L 0,8 UG/L 0.1 UG/L 200 UG/L 60 UG/L 2.5 UG/L 200 UG/L EtD072360 17-Apr-96 17-Apr-96 17-Apr-96 18-Apr-96 18-Apr-96 18.Apr.-96 29-May-97 LOWER POND FC-143 RT 33 STREAM SAMP FC-143 UPPER POND F0143 MW-AJP FC-143 MW-MGM FC-143 MW-TWW FC-143 LOCAL LANDFILL W.

AR226-2544 UNITED STATES ENVIRONMENTAL PROTECTION A6ENCY REGION II!

AR226-2674 64 AR226-2674 PROJECT LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 SRCNAME FBLK-2 FBLK1 FBLK1 FBLK1 FBLK1 FBLK1 FBLK1 FBLK2 FBLK2 FBLK2 LHPSD1 LHPSD2 LHPSD3 LHPSD5 LHPSDTW1 LHPSDTW10 LHPSDTW11 LHPSDTW12 LHPSDTW2 LHPSDTW3 LHPSDTW4 LHPSDTW5 LHPSDTW6 LHPSDTW6 LHPSDTW9 LHWAE1 LHWAFBLK LHWAFBLK1 LHWAFBLK3 LHWAFBLK4 LHWAN1 LHWANE1 LHWANE1 LHWANE2 LHWANW1 LHWANW1 C8 results Envista 111104.xls wwo THEME Blank Water Blank Water Blank Water Blank Water Blank Water Blank Water Blank Water Blank Water Blank Water Blank Water Drinking Water Drinking Water Drinking Water Drinking Water Groundwater Groundwater Groundwater Groundwater Groundwater Groundwater Groundwater Groundwater Groundwater Groundwater Groundwater Groundwater Blank Water Blank Water Blank Water Blank Water Groundwater Groundwater Groundwater Groundwater Soil Soil I3ATESMPL SMPLT 8/23/2002 FB 8/20/2002 FB 8/21/2002 FB 8/22/2002 FB 8/26/2002 FB 8/28/2002 FB 8/30/2002 FB 8/21/2002 FB 8/27/2002 FB 8/29/2002 FB 8/21/2002 FS 8/21/2002 FS 8/21/2002 FS 8/21/2002 FS 8/22/2002 FS 8/22/2002 FS 8/21/2002 FS 8/21/2002 FS 8/22/2002 FS 8/22/2002 FS 8/23/2002 FS 8/23/2002 FS 8/22/2002 DUP 8/22/2002 FS 8/22/2002 FS 8/30/2002 FS 8/23/2002 FB 8/26/2002 FB 8/28/2002 FB 8/29/2002 FB 8/29/2002 FS 8/20/2002 FS 8/22/2002 FS 8/30/2002 FS 8/29/2002 FS 8/29/2002 FS SAMPLEJMUMBER WWO-K-FBLK-2 WWO-K-FBLK1 WWO-K-FBLK1 WWO-K-FBLK1 WWO-K-FBLK1 WWO-K-FBLK1 WWO-K-FBLK1 WWO-K-FBLK2 WWO-K-FBLK2 WWO-K-FBLK2 WWO-D-LHPSD1 WWO-D-LHPSD2 WWO-D-LHPSD3 WWO-D-LHPSD5 WWO-G-LHPSD-TW1 WWO-G-LHPSD-TW 10 WWO-G-LHPSDTW11 WWO-G-LHPSDTW12 WWO-G-LHPSD-TW2 WWO-G-LHPSD-TW3 WWO-G-LHPSD-TW4 WWO-G-LHPSD-TW5 WWO-G-LHPSD-TW6-2 WWO-G-LHPSD-TW6 WWO-G-LHPSD-TW9 WWO-G-LHWAE1 (21-26) WWO-K-LHWAFBLK WWO-K-LHWAFBLK1 WWO-K-LHWAFBLK3 WWO-K-LHWAFBLK4 WWO-G-LHWAN1 (17-22) WWO-G-LHWANE1 (21'-27') WWO-G-LHWANE1 (56--58-) WWO-G-LHWANE2 (20.7-25.7) WWO-S-LHWANW 1(0.1 -0.5) WWO-S-LHWANW1 (5.0-5.5) FOP BOTT 21 17 21 56 20.7 0.1 5 Page 1 1^VWO QUALJIMHOUSE REVIEW METHODNO PREPMTHD 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 4500-CN D 4500-CN D 4500-CN D None 8321 A 8321A 8321A 4500-CN D 8321A 01M-008-046 None 01M-008-046 None 01M-008-046 None 01M-008-046 None 4500-CN D 8321 4500-CN D 8321 PREPREP NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS NS DRY 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 0 0 LABNUMBER L33596-12 L33585-2 L33585-9 L33596-8 L33605-3 L33615-4 L33619-4 L33585-3 L33605-5 L33615-6 L33585-4 L33585-5 L33585-6 L33585-7 L33596-3 L33596-1 L33585-10 L33585-8 L33596-2 L33596-5 L33596-11 L33596-10 L33596-7 L33596-6 L33596-4 L33619-3 FHC8H-1 FHC9F-1 FHC9G-1 FHC9L-1 L33619-1 L33585-1 L33596-9 L33619-2 FHK64-1 FHK65-1 RSLTMOD < < < < < < < < < < < < < < RESULT 3650 4260 952 8090 810 1100 1730 824 80.6 4170 12300 6260 1230 1150 812 416 0.020 0.020 0.020 0.020 50800 5580 662 1280 110 6.1 UNIT NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L NG/L UG/L UG/L UG/L UG/L NG/L NG/L NG/L NG/L UG/KG UG/KG MDL PQL 50 50 50 50 50 50 50 50 50 50 500 500 100 500 500 500 500 50 50 500 5000 500 500 500 500 50 0.020 0.050 0.020 0.050 0.020 0.050 0.020 0.050 5000 500 50 500 0.79 11 0.17 2.4 DUPNO 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 C8 results Envista 111104.xls Page 2 PROJECT LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 LH DELINEATION 8/02 MOU SAMPLING 2Q04 WWO MOD SAMPLING 2Q04 WWO MOU SAMPLING 2Q04 WWO SRCNAME LHWANW1 LHWANW1 LHWANW1 LHWANW1 LHWANW1 LHWANW1 LHWANW1 LHWANW1 LHWAS1 LHWAS2 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWASW1 LHWAW1 LHWAW2 EDDYEE FBLK-4 FBLK3 C8 results Envista 111104-xls wwo THEME DATESMPL SMPLT Soil 8/29/2002 FS Soil 8/29/2002 FS Soil 8/29/2002 FS Soil 8/29/2002 FS Groundwater 8/29/2002 FS Soil 8/29/2002 FS Groundwater 8/29/2002 DUP Groundwater 8/29/2002 FS Groundwater 8/28/2002 FS Groundwater 8/27/2002 FS Soil 8/23/2002 FS Soil 8/23/2002 FS Soil 8/23/2002 FS Soil 8/23/2002 FS Soil 8/23/2002 FS Soil 8/23/2002 FS Soil 8/23/2002 FS Soil 8/23/2002 FS Groundwater 8/23/2002 FS Soil 8/26/2002 FS Soil 8/26/2002 FS Groundwater 8/26/2002 FS Soil 8/26/2002 FS Groundwater 8/26/2002 FS Soil 8/26/2002 FS Groundwater 8/28/2002 FS Soil 8/28/2002 DUP Soil 8/28/2002 FS Groundwater 8/28/2002 FS Soil 8/28/2002 FS Groundwater 8/28/2002 FS Groundwater 8/29/2002 FS Groundwater 8/29/2002 FS Drinking Water 6/30/2004 FS Blank Water 6/30/2004 FB Blank Water 6/29/2004 FB SAMPLE_NUMBER WWO-S-LHWANW1 (10.0-10.5) WWO-S-LHWANW 1(15.0-15.5) WWO-S-LHWANW1 (20.0-20.5) WWO-S-LHWANW1 (21.0-21.5) WWO-G-LHWANW1 (19-25) WWO-S-LHWANW1 (25.0-25.5) WWO-G-LHWANW1 (24-29)-2 WWO-G-LHWANW1 (24-29) WWO-G-LHWAS1 (25-30) WWO-G-LHWAS2 (25-30) WWO-S-LHWASW1 (0.3-0.9) WWO-S-LHWASW1 (5.0-5.6) WWO-S-LHWASW1 (11.2-11.7) WWO-S-LHWASW1 (15.5-16.0) WWO-S-LHWASW1 (22.1 -22.6) WWO-S-LHWASW1 (26.5-27.0) WWO-S-LHWASW1 (30.0-30.5) WWO-S-LHWASW1 (30.5-31.0) WWO-G-LHWASW1 (28.5-33) WWO-S-LHWASW1 (37.0-37.5) WWO-S-LHWASW1 (37.5-38.0) WWO-G-LHWASW1 (35-40) WWO-S-LHWASW1 (44.3-44.5) WWO-G-LHWASW1 (40-45) WWO-S-LHWASW1 (47.5-48.0) WWO-G-LHWASW1 (45-50) WWO-S-LHWASW1(53.5-54.0)-2 WWO-S-LHWASW1 (53.5-54.0) WWO-G-LHWASW1 (50-55) WWO-S-LHWASW1 (55.5-56.0) WWO-G-LHWASW1 (55-60) WWO-G-LHWAW1 (29-34) WWO-G-LHWAW2 (33-38) WWO-D-EDDYEE WWK-K-FBLK-4 WWK-K-FBLK3 TOP BOTTO 10 1 15 1 20 2 21 2 19 25 2 24 24 25 25 0.3 5 11.2 1 15.5 22.1 2 26.5 30 3 30.5 28.5 37 3 37.5 35 44.3 4 40 47.5 45 53.5 53.5 50 55.5 55 29 33 0 0 0 Page3 a^^&stZis^^^fi^x^^'s'MS^^iii&^'&s^^^sai^^^^^s-^aia;!