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Lt ep 3M SRM Coerporate Toko and E3MmCaee, oiling 022006508 ARRZ6 . 362% feczpuen = ed a Peaieg 128 06FEIZY Aili on BEH9-0206- 15355 > E+ 3 on ime Document Processing Center eW[ ashaingion DC-- 20460-0001 Contain pyey cCay =2S Neca RE: TSESHCOA-SI(0E0)LSe1p3p4l6e5m8ntal Noss: Nemethylpefluoroosans slfonamidociano, Docket No.

O TLeLL. 3M de JeanB.Sweeney yn 3MEnvironmental,Healthand EEaR `3M Cente, Bulking0224-05Wb3 Certified Mail RECEIVED anet Coll 09JUL-1 AM 6: 0L June 25,2009 FEHQ Go ALae-3897 NocBt Document Processing Center EPA East -- Room 6428 Attn: Section 8() Office ofPollution Prevention and Toxics,US EPA Washinglon DC 20460-0001 [HNOE EA 1200 Pennsylvania Avenue NW -213 Re: TSCA 8() Substantial Risk Notice: Supplemental to Docket No.

FINAL REPORT EpiMdeedmiicoalloDgye,pa2r2t0m-e3nWt-05 3M Company St.

TNO report Transcriptome analysis of effects of Fenofibrate or PFOS in intestine of ApoE3L.CETP mice TNO Metabolic Health Research Zernikedreef 9 P.O.

Taft/ Taft Stettinius & Hollister LLP 425 Walnut Street, Suite 1800/ Cincinnati, OH 45202-3957 / Tel : 513 .381 .2838 / Fax : 513 .381 .0205 /www.taftlaw.com Cincinnati / Cleveland / Columbus / Dayton / Indianapolis / Northern Kentucky / Phoenix / Beijing ROBERT A BILOTT 513.357 .9638 biloft@taftlaw .com ~ ~c~Q~ ~~f373 s.., -4"Q-~' 3957 March 6, 2009 TSCA Confidential Business Information Center (7407M) EPA East - Room 6428, Attn : Section 8(e) & FYI U .S.

. 25 3M Environmental Laboratory OB Final Report- Analytical Study Single-dose Intravenous Pharmacokinetic Study of T-6049 in Rabbits In-Vivo Study Reference Number: HWI#6329-129 Study Number: AMDT-112294.1 Test Substance: FC-95 (T-6049) Name and Address of Sponsor: 3M SCD Division 367 Grove Street St.

SSSCREmRE tIe ENoRoong RIEOR"G3/6,7 3M PWoFrOkSin(gppMb)emLeovrealsndinuCmurorneDnattaanQduaHliisttoyrAicsaslesHsummeantn (of the Mean Populations) and Range of `This report documents Battelle's evaluation of the statistical quality and defensibility of 12 data sources ofserum perfluorooctanesulfonate (PFOS) levels found in non- occupational human populations.

AR22%-01l ACUTE TOXICITY TO AQUATIC INVERTEBRATES (E.G.

BIODEGRADATION FFiEs=3 TEST SUBSTANCE Identity: Perfluorooctanesulfonate, Ammonium salt; may also be referred t1o,1a,s2,P2,F3O,3S,4N,H4,,5",5s,a6l,t 6o,r7,F7C,-89,38.,8-(h1e-pOtacdteacnaefsluulcfroon-i,caamcimdo, nium salt, CAS # 29081-56-9) Remarks: The test sample is a mixture of the test substance in isopropanol and water (25% test substance, 20% isopropanol, 55% water).

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: 5p AR 226 _ 10] MR U2 "Toxicology and Descriptive Biology Key Elements Acute Toxicity Data Exists x Repeated Dose Toxicity x Developmental Toxicity x Key Findings Ei - a2 Low to moderate toxicity: oral/dermal/inhalation Irritation potential defined Not a sensitizer Oral/dermal/inhalation rodent/non-rodent Liver primary target organ Potency defined Oral/inhalation rat/rabbit = = s 3% ~~ = Z- 58 8 Fetus not more sensitive than maternal Nanootmaaslsioecsiated with structural - "nntain NO CBI | Toxicology and Descriptive Biology Key Elements Reproductive Toxicity Genetic Toxicity Ecotoxicity - Acute Data Exists - x x Key Findings Reproductive organs not a target Functional reproduction not defined Point mutation - Ames negative Chromosomal effects- in vivo, in vitro - negative Not a genotoxic agent .

SE AR226 _ 1168 : OCT 25 002 THIRD QUARTER 2002 SURFACE WATER AND GROUNDWATER MONITORING REPORT "| FOR WASHINGTON WORKS FACILITY AND LOCAL, LETART AND DRY RUN LANDFILLS WASHINGTON, WV Date:October 2002 Project No.: D6WW7423.01 18983635.20000 `CORPORATE REMEDIATION GROUP AnAlliance between DuPont and URS Diamond Barley Mill Plaza,Building 27 Wilmington, Delaware 19805 o =3 = x5 = CONTAIN NO GBI 000103 : Surtace water And Groundwater Moniorng Report Table of Contents TABLE OF CONTENTS 10 IEOGUCHOR. rtrtrrrsssssssssnsnel 2.0 C-8 ADAIYtCal REDOING... 2 3.0 Washington WOrkS FACIIIY crrrrevsrnns3 . 40 LOCA LAME.

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AR&8G - 1286 March 31,2003 To: UM.aSr.yEFn.viDroomnimneinatkal Protection Agency EPA East (Mail Code 7405M) W1a2s0h0iPnegntnosny,lvDaCnia20A4v6e0nue, NW.