AVKatheErinepE.iRdeeed, PAD.

C r 3M Spcei.ltyMattriah 3sMt PCaeunlteMrN 55144-1Ooo 651 733 1110 January 3,2003 Document Control mce @CO) Oflice of Pollution Prevention and ToxicS (OPPT) US Environmental Protection Agency EPAEast,Room6428 1201 Constitution Avenue,NW Washington,DC 20460 Attentiox Docket No.AR-226 andthe FYIDocket This continues3Ms voluntary submissionsof data o n p ~ m t a nseulfonatea and related compounds, as part of our ongoing dialogue with EPA regarding fluomhemi&.

A Pharmacokinetic Study of Potassium Perfluorooctanoate in the Cynomolgus Monkey Southern Research Institute Study ID: 9921.4 January 14,2003 Final Report on A Pharmacokinetic Study of Potassium Perfluorooctanoate in the Cynomolgus Monkey To: 3M Corporation P.O.

A Pharmacokinetic Study of Potassium Perfluorooctanesulfonate in the Cynomolgus Monkey Southern Research Institute Study ID: 9921.6 April 22,2003 Final Report on A Pharmacokinetic Study of Potassium Perfluorooctanesulfonate in the Cynomolgus Monkey To: 3M Corporation P.O.

ARR 1843 ' i APILOTREPRODUCTsIoOsN; STUDYWITHTHE MALLARD FINALREPORT WILDLIFE INTERNATIONAL, LTD PROJECT NUMBER: 434105 MLAB REQUESTNO.UZ3 FRA Guten714 ' AUTHORS:RSaeTaronmmPo.BnGdealLvlaaVghanesrkoven STUDYINTIATIONDATE: erry 28,200 STUDY COMPLETION DATE: December 15,2003 Submitto Envi5ra3o5vmBCoeoAnpotvrLsiaeonbor Sepa,Mims $5106 Wildlife International, Ltd.

pros AREPRODUCTION STUDYWITH THE MALLARD FINAL REPORT WILDLIFE INTERNATIONAL, LTD, PROTECT NUMBER; 454-109 SMLAB REQUEST NO, 12723 FIERAGuideline 714 ECDGuideline 206 AUTHORS: SJWVeoakaomPnno.b.nGedaDrl1le.avgVehaenfrioven STUDY INITIATION DATE: Janay 2,201 STUDY COMPLETION DATE: Augist 21,2003 [-- Env5sivrCoothnrAiavabenoniry St Pa Mines 5106 Wildlife International, Ltd.

--- Fos: APILOT REPRODUCTION STUDY WITH THE `NORTHERN BOBWHITE FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

February 1, 2005 Data ValOiadkatdiaolnefPorroPjeFcOtSIPFOA (MDH Sample Numbers 200501211-200501219) +dSe2almivCpelrueentdirldeicarneeaiclptytls:yisf.Sraommptlheesfiweeldreburtewcesirveednoitnognooicde.condSiatmiopnl.esSwaemrpelesstowreedreat C JtHoaonltuhdaeirnlygab2To7ri,amt2eo0sr0:y5.oSnaTJmhapenluaeansarlywye2sr5ie,s 2dc0ao0lt5le.ecwtaeAsdnaJwliaytnshuiisanro1yf42td5h,aey2ss0a0omf5plsaeansmdptwloeeokrcepolldaoeclaeivaenred No data were qualified.

AR226-2251 Catherine A Barton ^ 01/30/2002 05:12 PM To: cc: Subject: Mark H Russell/AE/DuPont@DuPont Robert F Pinchot/DEV/AE/DuPont@DuPont, Andrew S Hartten/AE/DuPont@DuPont, Theodore H Carski/AE/DuPontQDuPont Re: Draft modeling report Q Mark, Thanks so much for your great work.

AR226-2802 TRADE SECRET Study Title H-24648 and H-24020: Repeated-Dose Oral Toxicity Study 14-Day Feeding Study in Mice Laboratory Project ID: DuPont-5206 AUTHOR: Susan A.

TRADE SECRET AR226-3159 Study Title H-23926: Biopersistence Screening 10-Dose Oral Gavage Study in Rats Laboratory Project ID: DuPont-2920 AUTHOR: Carol Finlay, B.A.

AR226-3169 TRADE SECRET Study Tide H-24615: Static, Acute, 96-Hour Screening Test with Pimephales promelas Laboratory Project ID: DuPont-5019 AUTHOR: Robert A.

26-Week CapsuleToxicitSytudywithPerfluorooctanesulfoAncicdPotassiumSalt (PFOS) inCN-nomolausNlonkeys CurrentSummary asof,Nfav4,2000 T'hepurposeof thistudywas toidentiftyheearliecsltinicalmleyasurablebiologicraelsponsefrom repeateddailyexposure topotassiumperflucrooctanesulfonate(PFOS) and to correlatethisresponse to set= conc@-nrtabonfsorpurposesof riskassessmentard medicalmonitoringof exposedpopulations.

Final Report Mortality of Employees of an Ammonium Perfluorooctanoate Production Facility JessicaI.

P.