AR226-2549 April 16, 2001 Mr, William Wentworth U.S.

AR 226 _27/8 + Cabot Cra copron fiL926 S54Regulatory Services Sa < 0 RECEIVED SANITIZEOD5JU4 10 AMID: 17 % Ei Ci. ba Eo.

TRADE SECRET AR226-3179 DuPont-6818 Study Title H-24616: Static, Acute, 96-Hour Screening Test to Pimephales promelas Laboratory Project ID: DuPont-6818 AUTHOR: Daniel J.

p. 1 ACUTE TOXICITY TO THE MIDGE (CHIRONOMUS TENTANS) TEST SUBSTANC E Identity : Perfluorooctanoic acid, ammonium salt ; may also be referred to as PFOA, PFOA ammonium salt, Ammonium perfluorooctanoate, FC-116, FC-126, FC-169, or FC-143 .

laft/ A 425Walnut Set, Sue 1800/ Ciniat, OH 45202-3957 Tl 513.381.2638 ox: 513.381.0S2t05eirnsa& tltoro9m - Ciocinnat Clestand Columbus.Danndanapols/Nerthern Kentucky Phoeic Ben maanmeon atin con I THEE I ERA E o2 .

---A TCCoorrppoorErataeteTPHaetaAot RSePhysicos n,ne 1oCuosneMse2$052183:032220 F=YAIR-202560-p0y0-0132078 So Htc Depriet VoL TI April 21, 2000 (81000000018) Attachments To April 21, 2000 Letter to C.

Jp SpTsEN.T, { =3 emo August 10, 2001 VATEDSTATES ENROPROMTECE TIONN AGET NCAYRA2:t2Lv6)_ 103) WASHINGTOND.

, A226 _ lle 4 `OHIO ENVIRONMENTAL PROTECTION AGENCY | MEETING COLUMBUS, OHIO : July 24,2002 , LITTLE HOCKING WATER COMMENTS : BHoyclkeitntegr WdaatteedrFAesbsroucairatyi2o1n,, 2r0e0q2u,esMtre.d tKheavtitnheHoOphpieorE,nevnivriornomnemnetnatlalPrcootuencsteilofnorAtgheencLyittle enter into aconsent order with DuPont for ofthe contaminationofthe "watersof the the purposeof State" by C-8 establishing thenatureand impacted aquifers in Ohio.

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como ovfro ree Hq RST lh. rew ge A k mBeoormm TAFT, STETTINIUS & HOLLISTERLLP 425 WALNUT STREET, SUITE 1800 CINCINNATIs,eOaHmIaOn45202-3957 Fasosn nm Sa am A Fra , Aezze- - 1714 April 21, 2004 TELECOPY AND FEDERAL EXPRESS Dr.

BACK TO MAIN DIETARY ACUTE MALLARD DUCK STUDY REVISED Tissue analysis is now included.

3M Medical Department Study: T-6889.3 3M Medical Department Study: T-6889.3 Analytical Report: FACT-TOX-026 LRN-U2782 Analytical Report: FACT TOX-026 LRN-U2782 Study Title 26-Week Capsule Toxicity Study with Ammonium Perfluorooctanoate (APFO/POAA) in Cynomolgus Monkeys Amended Analytical Laboratory Report Title Determination of the Presence and Concentration of Perfluorooctanoate Fluorochemical in Liver, Serum, Urine and Feces Samples Data Requirement Not Applicable Author 3M Environmental Laboratory Analytical Phase Completion Date Juant seig1n1in, g2001 Performing Laboratories Liver, Serum and Urine Analyses Feces Analyses 3M Environmental Laboratory Building2-3E-09, 935 BushAvenue St.

Sponsor: 3M St.

"b5 Xenochemical Receptor trans-Activation by Perfluorooctane-based Chemicals "r-_ _5-._- _j,__ "7"--(-o_XO -_5 / Co_, _ J -1_-_. 3 "n,\-b_5.

STUDY TITLE Extraction of Potassium Perfluorooctanesulfonatefrom Egg Membrane, Albumen, and Yolk for Analysis Using HPLC-ElectrosprayMass Spectrometry DATA REOUIREMENTS Analytical Method Requirements STUDY DIRECTOR Sean Gallagher STUDY COMPLETED ON September 06,2001 /- PERFORMING LABORATORY / TESTING FACILITY Centre Analytical Laboratories, Inc.