AR226-2430 Ht^'-f^ INTEROFFICE MEMORANDUM c^ TOt WALTER M.

AR226-2467 "Roger J.

FOR DU PONT USE ONLY AR226-2954 Du Pont HLO 19-91 Study Title Skin Sensi'tizati'on Test w1t)fB|in Guinea Pigs Study Coinpleted On March 25. 1991 Contracting Laboratory Pharmakon Research International, Inc.

CONFIDENTIAL AR226-3132 -J^/SJ 3^ DPT 443/984760 TOXICTTY STUDY BY ORAL ADMINISTRATION TO CD RATS FOR 4 WEEKS Sponsor DuPont Specialty Chemicals; Jackson Laboratory, Chambers Works, Deepwater, NJ 08023, U.S.A.

ACUTE TOXICITYTO AQUATIC INVERTEBRATES - Ceriodaphnidaubia TEST SUBSTANCE IdentityN:-Ethylperfluorooctanesulfomnaaymaildseo;be referrteodas U 1464, ETFOSA, ETPOSA, F-6309, orFX-1 2. (1Octanesulfonamide,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluo ro-N -ethyl-C,AS # 4151-50-2) Remarks: Materialisa white solid.Sample purityand lotnumber were not recorded.

CORNINGHazleton MUTAGENICITY TEST WITH T-6357 IN THE SALMONELLA - ESCHERICHL4 COLIMAMMALIAN-NECROSOME MUTATION ASSAY FINAL REPORT AUTHOR Timothy E.Lawlor,M.A.

TOXICITYTO AQUATIC PLANTS TEST SUBSTANCE IdentitAy:mixturceontainipnegrfluorooctanesulwfhoincahtmea,y alsobe referredtoas PFOS, FC-95,oras a component ofFC-203. (1Octanesulfoniaccid)(CAS # 2795-39-3).

g An Official Journalofthe SER RN Supplement Ct AR226-017 BEST COPY AVAILABLE A

PRIZE 20% 7 CHRONIC TOXICITY TO FRESHWATER INVERTABRATES (Daphnia magna) TESTSUBSTANCE Identity: Perfluorooctanesulfonate; FC-95. (1-Octanesulfonic may acid, a1l,s1o,2b,e2.r3e,f3e,r4r,e4d,5t,o5,a6s.6P,7F.O7,S8.o8r.8- heptadecafluoro-, potassium salt, CAS# 2795-38-3) 3ReMmlaort knsu:mbTehre21l7e.st sSuabmsptlaencweaiss astwohrietdeupnodwedrera.mbiSeanmtpcloendwiatsiontsakperniofrrtoom etelsetmienng.taPluraintayldyesteesrmteicnhendiqtuoesb.e 90.49% by LC/MS, 'H-HMR, '*F-NMR and METHOD Method: 1193-87 OPPTS 850.1300, OECD Guideline 211, and ASTM Standard E Type: Semi-Static Life-Cycle Toxicity GLP: Yes YSpeeacriceosm:pDlaepthendi:aSmtaugdynacompleted 1999.

, 3M MEDICAL DEPARTMENT, CORPORATE TOXICOLOGY Protocol for Study No.

CORNINGHazleton MUTAGENICITY TEST ON o T6292 ; IN AN IN VIVO MOUSE MICRONUCLEUS ASSAY EINALREPORT AUTHOR Hemalatha Murli, Ph.D.

AR 226 _0821 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) IESTSUBSTANCE ~~~ 00000 Identity: A mixture containing perfluorooctanesulfonate; may also be referred to as PFOS, FC-95, or as a component of FC-206CF or FC-206CF-X. (1-Octanesulfonic acid) (CAS # 2795-39-3).

AR 226 _ 0292 ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity: A mixture containing perfiuorooctanesulfonate, which may also be . referred to as PFOS, FC-95, or as a component of FC-3017. (1Octanesulfonic acid) (CAS # 2795-39-3).

AR226-3039 Study Title Approximate Lethal Dose (ALD) of H-21460 in Rats Laboratory Project ID HaskeH Laboratory Report No. 176-96 Author Tracy A.

AR226-3186 TRADE SECRET Study Title H-24616: Subchronic Toxicity 90-Day Gavage Study in Rats with One-Generation Reproduction Evaluations Volume 3 of 5 Laboratory Project ID: DuPont-4739 DuPont-4739 TEST GUIDELINES: U.S.