International Research and Development Corporation SPONSOR: TEST MATERIAL: SUBJECT: 3M Company FM-3422 Acute Oral Toxicity (LD..J Study in Rats. 2 Director of Acute Toxicology and Special Studies (Study Director) Collaborators Gary Thompson, 3.S.

HAZLETON l a b o r a t o m e s a m e r g a . rs c . 3301 KINSMAN BLVD., P.O.

BACK TO MAIN June 25, 2001 Overview of the 3M Company Study "An Epidemiologic Analysis of Episodes of Care of 3M Decatur Chemical and Film Plant Employees, 1993-1998" The analysis of administrative databases, including health insurance claims data, have been infrequently reported in occupational epidemiologic research studies.

A R 2 2 6 -1 0 3 0 A 0 4 4 BACK TO MAIN POTENTIAL FOR ENVIRONMENTAL IMPACT OF AFA-6 SURFACTANT A Report for: PANARCTIC OILS LTD.

TECHNICAL REPORT SUMMARY BACK TO MAIN D ale 8/24/81 TO: TECHNICAL COMMUNICATIONS CENTER - 201-2CN (Important If report is printed an both sides o f paper, send two copies to TCC.)

BACK TO MAIN 3M Medical Department Study: T-6295.10 Analytical Report: FACT TOX-099 LRN-U2400 Study Title Oral (Stomach Tube) Developmental Toxicity Study of PFOS in Rabbits Analytical Laboratory Report Title Determination of the Concentration of Potassium Perfluorooctanesulfonate (PFOS) Fluorochemical in Rabbit Liver and Serum Specimens Data Requirement Not Applicable Author 3M Environmental Laboratory Analytical Phase Completion Date at signing Performing Laboratories Liver and Serum Extractions Liver and Serum Analyses Pace Analytical Services, Inc.

AR036-O3& BIODEGRADATION TEST SUBSTANCE Identity: N-methylperfluorooctane sulfonamidoethanol; may also be referred to as N-MeFOSE Alcohol, FC-790, or FM-3925. (1Octanesulfonamide, N-methyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-N-(2-hydroxyethyl)-, CAS # 24448-09-7) Remarks: Material is an off-white, waxy solid.

AttX-03%3 ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: athPoceeinadrfse,luic1Poo,Fr1soD,ad2Sfe,l2u,c,oaF3rn,Co3e--,s,14u2a,4l0mf,o,5mno,5aor,tn36eiM,,u6am,7Sm,as7mma,8oitp,,n8leiC,u9AmJ,29S9,s1#0a05lt6,;-171m09.

AR AA6 _ 0 58f TSCA NCIC Notification Form for CBI Documents ftDocket Number: R 3^1 io Document Control Number: 2 Q Q O Q a a > O O o l Document Date: ^ " Si' Document Type: _____ >C> CCc=a3 rc "--Otmo S iim - c> ro CD The d o c um en t referenced a bo ve is claimed a s confidential business information (CBI) u n d e r S e c t io n 14 o f the To x ic S u b s ta n c e s C o n tro l A c t (TSCA).

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"f\R. cZ fa U 03 To: Mary Dominiak/DC/USEPA/US@EPA, oppt.ncic@epamail.epa.gov cc: Subject: DuPont submission to AR-226 To : Mary F.

f fi# - 3-T7 SRPT T-76UI MIN 315/022356 PERFLUOROOCTANESULFONYL FLUORIDE (POSF) T ~lbbl3> IN VITRO MAMMALIAN CHROMOSOME ABERRATION TEST IN HUMAN LYMPHOCYTES Sponsor 3M Center 3M Corporate Toxicology Building 220-2E-02 St Paul MN 55133-3220 USA Page 1 of 31 Research Laboratory Huntingdon Life Sciences Ltd Woolley Road Alconbury Huntingdon Cambridgeshire PE284HS ENGLAND Report issued 22 October 2002 001542 MIN 315/022356 CONTENTS Page CONTENTS................................................................................................................................ 2 COMPLIANCE WITH GOOD LABORATORY PRACTICE STANDARDS..................... 4 QUALITY ASSURANCE STATEMENT................................................................................... 5 RESPONSIBLE PERSONNEL................................................................................................... 6 SUMMARY................................................................................................................................ 7 INTRODUCTION.................................................................................................................. 8 TEST SUBSTANCE.............................................................................................................. 10 EXPERIMENTAL PROCEDURE......................................................................................... 11 ASSESSMENT OF RESULTS................................................................................................... 15 MAINTENANCE OF RECORDS.............................................................................................. 15 RESULTS.............................................................................................................................. 16 CONCLUSION........................................................................................................................... 17 REFERENCES............................................................................................................................ 18 :2 : 001543 MIN 315/022356 COMPLIANCE WITH GOOD LABORATORY PRACTICE STANDARDS The study described in this report was conducted in compliance with the following Good Laboratory Practice standards, with the exceptions stated below, and I consider the data generated to be valid.

AR226-1536 The MSDS format adheres to the standards and regulatory requirements of the United States and may not meet regulatory requirements in other countries.

CC: R.

BEST COPY AVAILABLE 1663 GK001446 INTEROFFICE MEMORANDUM Datei From: Depti Tel No: 2 0 - Q c t - 1994 !