A R U 6 _ 0854 MICROBICS MICROTOX TOXICITY TEST T E S T SUBSTANCE__________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-603EF. (1Octanesulfonic acid) (CAS # 2795-39-3).

AKZS6 -0 7 7 MICROBIOS MICROTOX TOXICITY TEST TE S T SUBSTANCE__________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-787 or FC787X. (1-Octanesulfonic acid) (CAS # 2795-39-3).

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uaS" Estrous Cycling and Natural Delivery/Litter Observation Data FI Estrous Cycling Data, From Data Analysis Presented at EPA on August 30,2002" APFO Dose Group (mg/kg/day) 0 1 3 10 30 All 4-Day 14/30 19/29 9/30 15/29 15/30 Cycles 3-5 Day Cycles 24/30 26/29 21/30 25/29 27/30 Cycle Length (Days) 2 3 4 5 6 7 8 Mean Cycle Length (Days) S.D. 1 2 75 18 5 1 2 4.3 0.8 Incidence of Cycle Length Per Group 0 1 80 16 2 1 0 4.2 0.5 5 7 57 32 5 0 1 4.3 0.9 2 5 84 14 3 0 0 4.1 0.6 5 5 86 17 0 0 2 4.1 0.8 > 4 Days Diest. > 3 Days Est. > 4 Days Diest. > 3 Days Est. 2 17 5 25 Aberrant Cycles * Parental 11 13 15 FI 33 25 29 4 16 5 11 P E M D End in Estrous Distribution of Cycle Status at Start of 21-Day Evaluation Period, FI 14 12 8 10 11 14 62 2 0 15 13 16 13 Distribution Rats in Estrous at End of 21-Day Evaluation Period, FI 13 17 18 19 1 13 3 14 5 11 2 12 19 hO C-i; P '0 CD C--~5I I ro 2?

I Ok f t AKSLZG- 1131 REVISED DRAFT HAZARD ASSESSMENT OF PERFLUOROOCTANOIC ACID AND ITS SALTS U.S.

M&SL - 14-99 Review o f APME-Sponsored Kinetics I.

03/13/2003 10:06 oa/ia/oa os:09 UU DEP LEGAL SERUICES -> 915133010205 NO.129 304 026 8738 WV AIR QUALITY At.

AR226-1486 ENVIRONMENTAL AND HEALTH ASSESSMENT OF PERFLUOROOCTANE SULFONIC ACID AND ITS SALTS August 20, 2003 Prepared by 3M in consultation with Jack Moore, D.V.M., DABT, Hollyhouse, Inc.

* ^ Z Z - / C 23> C-8 IN OFF-PLANT WATER SYSTEMS NONE DETECTED IN UPSTREAM PUBLIC WATER SYSTEM, NONE DETECTED IN WASHINGTON WORKS' DRINKING WATER.

^4/2-226-/SS Report Mo.

ANALYTICAL METHOD VALIDATION FOR THE DETERMINATION OF PERFLUOROOCTANESULFONATE, POTASSIUM SALT (PFOS) IN PLANT TISSUES WILDLIFE INTERNATIONAL, LTD.

3M Lifetime Drinking Water Health Advisory for Perfluorooctanesulfonate Revision Date: April 19, 2002 Supercedes: July 7,1999 This document establishes a Lifetime Drinking Water Health Advisory (DWHA) o f 4 pg/L (ppb) for perfluorooctanesulfonate (PFOS).

PFOS: A DIETARY LC50 STUDY WITH THE NORTHERN BOBWHITE WILDLIFE INTERNATIONAL LTD.

PFOS: A PILOT REPRODUCTION STUDY WITH THE NORTHERN BOBWHITE FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

Fraunhofer ITEM Final Report 01 G 00 0 02 [Appendices A-D] 28 Day Repeated Dermal Contact Study of 3M Test Articles in Sprague-Dawley Rats Page 1 of 56 Appendix A: Test Sample Re-analysis [performed by 3 M ] Fraunhofer ITEM Final Report 01 G 00 0 02 [Appendices A-D] 28 Day Repeated Dermal Contact Study of 3M Test Articles in Sprague-Dawley Rats Page 2 of 56 Appendix A1 : 1st Test Sample Re-analysis Internal Correspondence TO: FROM: REGARDING: John Butenhoff November 14, 2000 Fred L.