.S.6 _05 RECEIVED oppi neic : i( 2000 SEP-6 PM12=56 \ 1 I

A R HHG - O &KQ ACUTE TO XICITY TO FISH TEST SUBSTANCE ______________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-185F. (1Octanesulfonic acid) (CAS # 2795-39-3) Remarks: The 3M production lot number was 1-2303.

AH A56 - 0730 ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE________________________________________ _ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-206 or L3243. (1-Octanesulfonic acid) (CAS # 2795-39-3).

Ak 2.6 - Q Z $ 0 ACUTE TOXICITY TO AQUATIC INVERTABRATES (DAPHNIA MAGNA) TEST SUBSTANCE____________________________________________ Identity: A mixture containing periluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was not noted.

ACUTE TO XIC ITY TO FISH (FATHEAD M INNOW ) TEST SUBSTANCE________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-603F. (1Octanesulfonic acid) (CAS # 2795-39-3).

y lK S _ 0 2 6 MICROBIOS MICROTOX TO XIC ITY TEST TEST SUBSTANCE______________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-603F. (1Octanesulfonic acid) (CAS # 2795-39-3).

AfL M 6 - 0 8 8 5 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEST SUBSTANCE______________________________________ Identity: Mixture containing perfluorooctanesulfonate which may also be referred to as PFOS, FC-95, or as a component of FC-3003. (1Octanesulfonic acid) (CAS # 2795-39-3).

, 3M Environm ental Technology and Services / f May 10, 2002 PO Box 33331 St.

RECEIVED o pp umi 2082 SEP 2 AN III!

Environmental Working Group ||Policy Memo: DuPont, Teflon, Water, Contamination, ...

; 9 pp 3M 3M General Offices Lm K n 55144-ioco 612 733 1110 AR226-1541 - 1003 - l RECEIVER oppt cm : 2003 OCT 2 9 A H i h 01 Bv Courier October 28, 2003 Document Processing Center - CBIC (7407M) 'hh Room 6428 East / Phone 202-564-8940 Attn: TSCA Section 8(e) Coordinator Office o f Pollution Prevention and Toxics US Environmental Protection Agency 1201 Constitution Avenue NW Washington DC 20460-0001 8 EHQ 0 y RE: TSCA 8(E) SUBSTANTIAL RISK NOTICE ON: 1-Butanesulfonamide, 1,1,2,2,3,3,4,4,4-nonafluoro-n-methyl ('N-MePFBA') [CAS 68298-12-4] 63 Dear Sir/Madam: 3M has received preliminary data for a combined repeated dose toxicity study with a reproduction/developmental toxicity screening test in rats conducted with a chemical intermediate, 1-Butanesulfonamide, 1,1,2,2,3,3,4,4,4-nonafluoro-n-methyl [CAS 68298-12-4] (N-MePFBA) indicating reproductive and possible neurotoxic effects.

Attachment 2 A & lltrlT lX CANCER PREVALENCE IN SUBJECTS EXPOSED TO ALKYLATED SUBSTANCES (PFAS) James Dahlgrsn M D', Ayman B Ibrahim M D1'2' 3, Ray Warshaw2, Karpreet Takhar MPH3 * i .

3M FLUOROCHEMICAL SUBMISSIONS February, 2002 - May, 2004 INDEX OF 3M'S 2002-2004 AR-226 DOCKET SUBMISSIONS BY DATE Back to Menu APRIL 2002 Click on Study Title to View Report April 2, 2002 April 2, 2002 Submission Cover Letter Final Report, Oral (Gavage) Two-Generation (One Litter per Generation) Reproduction Study of Ammonium Perfluorooctanoate (APFO) in Rats, Sponsor's Study Number: T-6889.6, March 26, 2002.

SPrimedica Argus Research Laboratories, Inc. 90S Sheehy Drive, Building A Horsham, PA 19044 Telephone: (215) 443-8710 Telefax: (215)443-8587 REPORT AMENDMENT 1 12 OCTOBER 2000 PROTOCOL 418-009 COMBINED ORAL (GAVAGE) FERTILITY, DEVELOPMENTAL AND PERINATAL/POSTNATAL REPRODUCTION TOXICITY STUDY OF N-ETFOSE IN RATS FINAL REPORT Attached is the corrected Text Figure 1 to the above-referenced final report.

ANALYTICAL METHOD VALIDATION FOR THE DETERMINATION OF PERFLUOROOCTANESULFONATE, POTASSIUM SALT (PFOS) IN ARTIFICIAL SOIL WILDLIFE INTERNATIONAL, LTD.