AA AZ6 - \ W r ^ V , : ^ -~ ~ ii5 z .

r ..... ..--

Katherine E.

(JS ESTAI y S MI D i t o ; E . 1. d u P o n t d e N e m o u r s & C o m p a n y INCORPORATED W i l m i n g t o n , D e l a w a r e 19898 PO LYM ER PRO D U CTS D EPARTM ENT E X P E R IM E N T A L STA TIO N PERSONAL AND CONFIDENTIAL cc: A.

-4 5 R C V 12 79 < M I> ESTABLISHED IBOi E I. du P o n t de N e m o u r s & C o m p a n y IN C O RPO R A TED W il m in g t o n , De l a w a r e 19898 POLYM ER PRODUCTS DEPARTMENT EXPERIMENTAL STATION PERSONAL AND CONFIDENTIAL cc: A.

NORTHERN KENTUCKY OFFICE SUITE 340 1717 OKIE HIGHWAY COVINGTON, KENTUCKY 41011-4704 606-331-2838 513-381-2838 FAX: 513-381-6613 DAYTON, OHIO OFFICE SUITE 900 110 NORTH MAIN STREET DAYTON.

Toxicological Summary AR226-1752 PFOS Dietary Chronic Definitive Reproductive Study: Northern Bobwhite Test Substance: Perfluorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro, potassium salt.

Northwest Bioanalytical Study No.

BACK TO MAIN 3M FLUOROCHEMICAL SUBMISSION TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE October 1987-October 2005 C lick on Study Title to V iew R eport PFOA Perfluorooctanoate 1.

Interoffice Correspondence cc : H.E.

A R m - 0 H6f| Attachments to Letter to C.

T V Uv t ) 0 '.c^ 'u l ^ f t ( * t c7 TERATOLOGY 50:19--26 (1994) A f W - 55^ Prevention of Fluvastatin-Induced Toxicity, Mortality, and Cardiac M yopathy in Pregnant Rats by M evalonic Acid Supplementation ROMAN V.

qrr Charles Auer 05/16/2000 11:11 AM RECEIVED O P P T HC1C 2000S E P -6 PH 12: 57 e2G 0 6 2 - 3 To: cc: Subject: Barbara Leczynski/DC/USEPA/US@EPA, Mary Dominiak/DC/USEPA/US@EPA, Frank Kover/DC/USEPA/US@EPA, Ward Penberthy/DC/USEPA/US@EPA, Karen Lannon/DC/USEPA/US@EPA Phaseout of PFOS fyi Forwarded by Charles Auer/DC/USEPA/US on 05/16/2000 11:17 AM Charles Auer 05/16/2000 11:06 AM To: Charles Auer/DC/USEPA/US@EPA, blnetti@iss.it, John.Bucdnl@ec.gc.ca, "IMCEAFAX-3001+5ECHADJICHRISTIDI+2C+20Konstantina-fax+5E3A23+5E3018662968+5E"@oecd.or g, shchung@me.go.kr, theresa.gilgallon@cec.eu.int, addeke@lss.it, karen_florlnl@edf.org, amst@baua.do.shuttle.de, bjorn.hansen@jrc.it, hasa@env.cz, mark.hyman@ea.gov.au, "IMCEAFAX-3001+5EICONOMOU+2C+20Maria+5E3A23+5E3016465123+5E"@oecd.org, geir.jorgensen@sft.telemax.no, Rainer-Kurt.Koch.RK@bayer-ag.de, Thaly.Lakhanisky@iph.fgov.be, ivarl@kemi.se, majka@bware.imp.lodz.pl, matejova.jana@flora.lifeenv.gov.sk, TM-TNG@mhw.go.jp, laurence.musset@environnement.gouv.fr, jrn@mst.dk, esa.nikunen@vyh.fi, caria.piccinni-leopardi@cec.eu.int, raimund.quint@bmu.gv.at, rosenbaum@biac.org, esilber@epi.umaryland.edu, urs.staempfli@buwal.admin.ch, nagata-reiko@miti.go.jp, roger_tregunno@detr.gsi.gov.uk, Hty@mst.dk, ungvary@elender.hu, kees.van.Leeuwen@rivm.nl, vickersc@worksafe.gov.au, jwillis@unep.ch, younesm@who.ch, Dian.TURNHEIM@oecd.org, Naoyuki.YASUDA@oecd.org, Lesley.ONYON@oecd.org, Oscar Hernandez/DC/USEPA/US@EPA cc: robert.visser@oecd.org, robert.donkers@cec.eu.int, Susan Wayland/DC/USEPA/US@EPA, William Sanders/DC/USEPA/US@EPA, Pep Fuller/DC/USEPA/US@EPA, milroy.breck@epamail.epa.gov, ig232001@wp-gate.bmu.de, Priscilla Flattery/DC/USEPA/US@EPA Subject: Phaseout of PFOS I would like to draw your attention to an important development in the US which concerns a persistent, bioaccumulative, and toxic chemical.

Report EO1-1256 PFOS: A Reproductiun Study with the Mallard Study Title A nalytical Phase Report for PFO S : A Reproduction Study w ith th e Mallard Data Requirement FIFR A Subdivision E, Section 7 1-4 O E C D Guideline 206 Author Lisa A.

January 10, 2005 Via Federal Express RECEIVED %(m I !