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3M FLUOROCHEMICAL SUBMISSION
TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE October 1987-October 2005
C lick on Study Title to V iew R eport
PFOA
Perfluorooctanoate
1. "Two-Year Toxicity/Carcinogenicity Study of Fluorochemical FC-143 [PFOA] in Rats," Review letter from Greg Sykes (Haskell Laboratory for Toxicology and Industrial Medicine) to Charles Reinhardt, October 29, 1987.
2. "Pathology Peer Review Report: 26-Week Capsule Toxicity Study with Ammo nium Perfluorooctanoate (APFO) in Cynomolgus Monkeys," Nancy A. Gillett (Sierra Biomedical), Covance Study No. 6329-231, February 3, 2000.
3. "H18636: Slide Review of pancreas lesions from DuPont APFO Study," E.E. McConnell and J.R. Foster, Study No. HN-18636, November 28, 2001.
4. "Review of proliferative lesions of the exocrine pancreas in two chronic studies in rat with ammonium perfluorooctanoate," S.R. Frame and E.E. McConnell, DuPont-13788, October 16, 2003.
5. "FC-143: Two Year Oral Toxicity-Oncogenicity Study in Rats Peer Review of Ovaries," Peter C. Mann (Experimental Pathology Laboratories, Inc.) and Steven R. Frame (DuPont, Haske Laboratory for Health and Environmental Science), DuPont-15261, June 25, 2004.
6. "Ammonium Perfluorooctanoate: Age Effect on the PFOA Plasma Concentra tion in Post-Weaning Rats Following Oral Gavage," Paul M. Hinderliter (DuPont), DuPont -15302, December 2, 2004.