FOR DU PONT USE ONLY AR226-2897 Copies t E.

Study Sponsor: Issu e Date: Docum ent Reference No.: ATOCHEM 4-Jun-92 AR226-2972 n.

AR226-3004 DuPont HLR2S7-S4 HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE STATIC.

M m 6 - 2l> 455 V l / u a * ,, 3-273 DuPont-9478 TRADE SECRET Study Title y^^j^^^yJ^HD aH^HurjatTtlOHapv^augbecShturdoymincRTatosxicity Volume 2 of 3 Laboratory Project ID: DuPont-9478 Test Guidelines: OUP.SP.TESPA87H0.e3a1l0th0E(1ff9e9c8ts) Test Guidelines AUTHOR: Gregory S.

15:8 vW ^ EPA/Fluoropolymer Industry Meeting I Introductions I Meeting Purpose I Introduction to the Fluoropolymer (FP) Industry I Fluorinated Processing Aids (APFO/PFOA) in Fluoropolymers I Discussion & Feedback ^ o-r-j mo Meeting Purpose I Provide Overview of FP Industry I Who, What, How, Critical Uses I Open Communication Channels I Describe What Industry Is Doing I Determine EPA Expectations & Plans I Regulatory Actions I International Coordination I Discuss Next Steps Contain NO GBi / S o cie ty of the P la s tic s Industry (SPI) Fluoropolym er M anufacturers Group (FMG1............ ............. _ _ , I A Special Purpose Committee of the SPI I The mission of the FMG is to promote the continued safe manufacture & use of fluoropolymers made using fluorinated polymerization aides (FPA) while establishing & supporting responsible care in the use of fluoropolymer products & minimizing the impact on the environment FMG Objectives for Meeting I Illustrate Necessity of the Continuing Safe Use of APFO I Demonstrate Industry's Safety & Health Awareness I Identify EPA Concerns FMG Members I Asahi Glass Fluoropolymers I Atofina I Ausimont I Daikin I DuPont & DuPont/Dow Elastomers I Dyneon (a 3M Company) Fluoropolymers & PFO Chem istry I APFO Vs.

AR226-2757 Fr " PONT USE ONLY E. l. du Pont de Nemours and Company Haskell Laboratory for Toxicology and Industrial Medicine Elkton Road, Newark, Delaware 19/11 HASKELL LABORATORY REPORT NO. 1005-80 Study initiated/Completed 10/'/80 - 10/9/80 Material Submitted by rolymer Products Dept, Washington Works Parkersburg, V/V EYE IRRITATION TEST IN RABBITS Procedure: One tenth milliliter of undiluted test material was placed i n t o ^ the right conjunctival sac of each of 2 male New Zealand Whi.eraobits.

AR226-2784 # x FOR DO POST OSE ONLY E.

AR226-3115 Huntingdon ,, .. ^ nSH~, 3' CONFIDENTIAL DPT478/992105 MOUSE MICRONUCLEUS TEST Sponsor DuPont Specialty Chemicals, Jackson Laboratory, Chambers Works, Deepwater, NJ 08023, USA.

b -- --------------------------------------------- ------------------------------------------------------------------------------ 498 fa ite 3 3 DuPont-13882 TRADE SECRET Study Title H-26137, H-26138, and H-26139: Repeated Dose Dermal Toxicity 28-Day Study in Male Rats Test Guidelines: U.S, EPA Health Effects Test Guidelines OPPTS 870.3200 (1998) OECD Guideline for the Testing of Chemicals Section 4: Health Effects, Number 410(1981) Author: Carol Finlay, B.A.

< AR226-3379 Development Of A Biologically Based Model To Describe Perfluorooctanoic Acid (PFOA) Kinetics P.M.

AR226-3395 Repeated Dose Oral Toxicity of 8-2 Telomer B Alcohol Range-Finding Study in Rats G.L.

ACUTE TO XIC ITY TO FISH (M UM MICHOG) TEST SUBSTANCE________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-780. (1Octanesulfonic acid) (CAS # 2795-39-3).

RECEIVED PFOS Ecotoxicological Testing Results OPlfyffQpprison of Effect Concentrations Calculated Using Different Sample Purity M H M rr^an {n fasured concentrations, except where * (nominal).

Analytical Report Fluorochemical Characterization of Aqueous Samples Decatur Outfall 001 FC Monitoring (E03-0326) Exygen Research Laboratory Report No.

rtR. & 6 _ 0 6 # / PFOS Acute Toxicity - / 000025 Interoffice Correspondence Subject : November 14, 1974 ire: H.