CLIENT PRIVATE AR3X-0ia PROTOCOL TITLE: Metabolism of T-6292, T-6293, T-6294, and T-6295 by Rat and Human Hepatocytes SRI Study No.

Quality Assurance Project Plan Multi-City Study Sampling Task (N100672) BACK TO MAIN Amendment 2 to Revision No.: 1 Effective Date: July 20, 1999 Page 1 o f \ l Amendment 2 to the Quality Assurance Project Plan and Associated SOP's for Empirical Human Exposure Assessment Multi-City Study Sampling Task To July 23,1999 Prepared by Battelle Marine Sciences Laboratory 1529 West Sequim Bay Road Sequim, WA 98382 360-681-3660 APPROVALS 3 ifd Gunster Sampling Task Leader Rosanna Buhl Battelle Sampling Task QA Officer 3 * 1 QMA* tjtyL de'----- --- ^ MMaarrcciaNishiolra y ^ Buaaititcenllce rPiruojjceucat iMvianuagceir 0 ^ u s a n Abogy Battelle Program QA Officer ___ jz iii Date 7 8-a~7-qq Date j/so /o / Date ns#5 *>/ **,+ < * * 1 ^ Date -f S y - t.

BACK TO MAIN ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEST SUBSTANCE_________________________________________ Identity: Perfluorooctanoic acid, tetrabutylammonium salt; may also be referred to as PFOA tetrabutylammonium salt, tetrabutylammonium perfluorooctanoate, or as a major component of L-13492.

/IfttiG -cm R OCTANOUW ATER PARTITION COEFFICIENT TEST SUBSTANCE_____________________________________________________ Identity: N-ethylperfluorooctane sulfonamidoethanol; may also be referred to as N-EtFOSE Alcohol or FM-3422. (1-Octanesulfonamide, N-ethyl1 ,1 ,2 ,2 ,3 ,3 ,4 ,4 ,5 ,5 ,6 ,6 ,7 ,7 ,8 ,8 ,8 -h e p ta d e c a flu o ro -N -(2 -h y d ro x y e th y l)-, CAS # 1691-99-2) Rem arks: Material is an off-white, waxy solid.

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f t k 26 - 0 ^ 0 0 BIODEGRADATION (MANOMETRIC RESPIROMETRY - ANAEROBIC) TEST SUBSTANCE___________________________________________ Identity: A mixture containing perfluorooctanesulfonate;, which may also be referred to as PFOS, FC-95, or as a component of FC-3041. (1Octanesulfonic acid) (CAS # 2795-39-3).

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UC DuPont-6711 Study Title 8-2 Telomer B Alcohol: Acute Oral Toxicity - Fixed Dose Method Laboratory Project ID: DuPont-6711 23E "Orn cn --^imO 32 3CST5p<yf^ 5 coQ o T est G u id elin e: OECD Guidelines for Testing of Chemicals Section 4: Health Effects, No. 420 (1992) A u t h o r : Carol Finlay, B.A.

L a rry R .

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gfltt Ml POUT USE ORLY AR226-2952 Du Pont HLR 101-91 Skin Irritation Test with in Rabbits Author John W.

AR226-3080 DuPont HLO-1997-00636 TRADESECRET g ta frjig s Toxicity o f H-22387 to the Freshwater Alga, Seknastrum capricormtom Haskell Laboratory Project IP Haskell Laboratory Outside Report No, 1997-00636 Tggg_ryij!

ii-/4Dio: suDcnromc toxicity 90-Day Gavage Study in Rats with One-Generation Reproduction Evaluations TRADE SECRET Study Title H-24516: Subchronic Toxicity with One9-G0-eDnearyaGtioanvaRgeepSrotudduyctiinonREatvsaluations Volume 3 of 5 Laboratory Project ID: DuPont-5386 DuPont-5368 AR226-3199 Test G u id elin es: U.S.

Aft _ 0 6 3 4 TOXICITY TO AQUATIC PLANTS TEST SUBSTANCE________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95 or as a component of FC-201AF. (1Octanesulfonic acid) (CAS # 2795-39-3).

_ 075S ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE_______________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203CE. (1Octanesulfonic acid) (CAS # 2795-39-3).