HAZLETON LABORATORIES AMERICA INC. 9 2 0 0 LEESBURG Tu ONPIKE VIENNA VIRGINIA 2 2 1BO U S A RAT TERATOLOGY STUDY T-3352 FINAL REPORT Submitted to 3M Comoanv St.

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r] (ss) 2=3 R236-03/0 IN VITRO MICROBIOLOGICAL MUTAGENICITY ASSAYS OF 3M COMPANY'S COMPOUND T-3609 Final Report September 1984 By: C U t ) Debra E.

Pathology and Toxlcotogy RHcar Laboratories, Inc.

JEFFERSON M ED ICA L COLLEGE of THOMAS JEFFERSON UNIVERSITY Rl2fe-0530 Daniel Baugh Institute of Anatomy Department o f Anatomy Office of the Director and Chairman Philadelphia, 19107 (215) 928-7820 November 12, 1982 Dr.

A R B fc -0 5 6 ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: Perfluorooctanoic acid, ammonium salt; may also be referred to as PFOA ammonium salt, Ammonium perfluorooctanoate, FC116, FC-126, FC-169, orFC-143.

AR226-3376 HASKELL LABORATORY Common Name: Ammonium Perfhiorooctanoate (C-8) Chemical Name: Octanoic add, pentadecafluoro-, ammonium salt CAS Registry No.: 3825-26-1 Chemical Structure: Physical Properties: OI cc f 3 - c f 2- c f2- c f2- c f2- c f2- c f 2 - - o -+n h 4 Form: Molecular W dght: Boiling Point: Melting Point: Density: White powder 431 Sublimes @ 110C -- -- Drinking Water Guideline (CEGW) 1 ug/L General Toxicity Ammonium perfluorooctanoate (C-8) has moderate acute oral toxicity with an LD50 in rats of 470 mg/kg 981b).

% AR706 -00/7 JEFFERSON MEDICAL COLLEGE of THOMAS JEFFERSON UNIVERSITY Daniel Baugh Institute of Anatomy Department of Anatomy Office of the Director and Chairman Philadelphia, 19107 (215) 928-7820 November 12, 1982 Dr.

AR2X-032 To : Study Files of Riker Experiments Nos. 068QTR0008 0680TR0010 0680TR0020 0681TR0095 0681TR0110 0680RR0018 From: U.

Internal Correspondence dc: V.

BACK TO MAIN ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE_____________________ Identity: Perfluorooctanesulfonylamido(ethyl)acetate; may also be referred to as PFOSAA, FC-128 or as the major component of FC-127, FC-129, FC-109, FC-109-X, FC-4351, or L-6778.

M 3 2 6 _ 0X37 ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE___________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was Belgium 2367.

V AR226-2385 PERSONAL AND CONFIDENTIAL CC: T.

AR226-2401 M INTEROFFICE MEMORANDUM Date: From: Dept: Tel N o : 31-May-1989 10:54am WILLIAM E CRAWLEY CRAWLEWE PPD~"TEFLON"TECH 304-863-2742 TO: ANTHONY J. tTONYJ PLAYTIS ( PLAYTIS ) Subject: C-8 Sampling We have decided that it is not necessary to continue sampling the Lubeck system for Q-8 to see the impact of the Supernate Pond closure.

AR226-2790 FOR DU PONT USE ONLY Approximate Lethal Concentration by Inhalation (ALC) of Ammonium Periluorononanoate (C-9) Haskell Laboratory Report No. 293-85 E.