Regional Office) + PNreosne-nDtautPioonastadnodcoutmheenrtsdo(caucmleundetsstdhoacturmeefnertesncferdomatoatthhaetciosmipnanaireesp,orptsluabmiitntecdotuonsEelPeAtc) * * DDooccuummeennttss ctohantceazrenisnugbjweocrtkt-oina-tptroorgnerye-scsli(eNnottperitvhiloeuggeh that DuPont will provide periodic `iulpdlastuebsmtiotErePpoArtosnownorsku-cihnw-porrogkrteossE,PpeAzwthheenNofvineamlber 10, 2004 presentation to EPA, aad * Supporting reports (e.g, lab analysis, tc) for blood monitoring results SummaryofCollection Process for Specific CategoricsofRequested Information t`Thheecldaoscsuamcetniotnslfiograttihiosn,saulbomnigswsiitohn wceozleleccotliloenoctfeddofcruommeraetvsiefworofmthiendidvoicduuamlesnitnstphreoCdoumcpedaniny most likely to possess such information. 3 r= HPATiTONtBtOGS.

"It is clear that at least some FTOHs break down," Thayer adds, noting that DuPont has shown that telomer 82 degrades to PFOA.

AR226-2068 l/i-7 a^ SAFETY, HEALTH AND ENVIRONMENTAL ^M) C8 AMMONIUM PERFLUORO--OCTANOATE FC-143 ANIONIC FLUOROCHEMICAL SURFACTANT i -1- MGF by 3M COMPANY o DuPONT AEL: 0.01 mg/M3 (0.56 ppb. 8 hr TWA) o IRRITANT via INHALATION, SKIN or EYE CONTACT o MODERATELY TOXIC (ORAL) o ACUTE OVER-EXPOSURE: LIVER INJURY o CHRONIC EXPOSURE - LIVER ENLARGEMENT - ELEVATED BLOOD FLUORINE LEVELS o NO KNOWN MEDICAL PROBLEMS FROM C8 (35 years) o C8 IS NOT: -ATERATOGEN - EMBRYOTOXIN - MUTAGEN I QKS 10/24/90 EID112755 ,, ..^^..

Mvlchreest DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware, Abstract A fluoroalkylethyl phosphate surfactant was evaluated in rats in 90-day, one-generati reproduction, and developmental toxicity studies.

I. duPont de Reaours and Conpany, Stine-Haskell P.O.

DuPont manufacturing facility located in Washington, W est Virginia. 3.

DuPont manufacturing facility located in Washington, West Virginia. 3.

According to DuPont, its melting point is 600 K (327 C; 620 F).

The incideneeof nodular hyperplasia in the liver (males: 1/50,0/50,2/50; females: 0/50,0/50, 3/50) was also slightly mcreased, though not statistically significantly (DuPont, 1987). . .

TRADE SECRET Study Title H-23271: Skin Irritation Test in Rabbits Laboratory Project ID: D uPont-1 161 D uPont-1161 AR226-3100 A u t h o r : Carol Finlay, B.A.

Development history PVDF has more than 70 years of development history, in 1944, the United States DuPont company successfully synthesize PVDF for the first time.

Pi significativi, forse, sono gli studi condotti nelle aree limitrofe agli stabilimenti della DuPont (Virginia, USA) dove si riscontr un significativo incremento di cancro alla prostata, e cancro agli organi riproduttivi femminili, rispetto gli indici di probabilit riportati per altri Stati americani.

The tumor incidences were outside the historical control incidence range for Haskell Laboratory, and in addition, age-adjustment statistics also supported the conclusion that the tumor incidences were elevated for the liver, pancreas, and testis (DuPont, 1993).

Other suppliers include DuPont MolykoteTM and Castrol BraycoatTM.

The incidence o f nodular hyperplasia in the liver (males: 1/50,0/50,2/50; females: 0/50,0/50, 3/50) was also slightly increased, though not statistically significantly (DuPont, 1987). > A ll o f th e other rem arkable tum or incidence values produced in this study w ere associated w ith endocrine or endocrinersensitive organs (DuPont, 1987): . :: " ?