There is danger of exposure to; tetraethyl lead in the manufacture of this material and of Ethyl Fluid which contains tetraethyl lead in high concen tration.

Hematologic changes are never seen in tetraethyl lead poisoning, and the compound which stabilizes lead in high concentration in the erythrocyte, when inorganic lead is absorbed, .is not formed or docs not enter the erythrocyte when the source of lead absorp tion is tetraethyl lead.

Moreover this matter 13 not an important problem at present* Obviously however* any regulations developed now in this field should avoid the use of the word "Ethyl Gasoline" since this is a patented name and therefore* will not apply to other gasolines containing lead tetraethyl.

Suggested Draft of Newa Letter For the past fifteen years the manufacture of lead tetraethyl has not been a source of great concern in relation to public or Industrial health* During that time manufacturing operations have been oarried out in only two states and under effective hygienic control* However* in the past month* as a consequence of attempts to manufacture lead tetraethyl without proper safe guards* the attention of the Public Health Service has been called to this problem* when several oases of poisoning were reported in connection with a plant that had been in continuous operation only two weeks.

XE 0022978 17 a ter from 3ludge pit of "B" building of Tetraethyl Lead plant of E.

CONCHJSION The toxicity of Lead tetraethyl has been shown to be greater than any of the substance* occuring in the process of its manufacture.

I# The history of exposure is not adequate* One cannot be certain that the patient was actually exposed to tetraethyl lead* It is assumed by the physicians, apparently, that the chief ex* posure to lead occurred through Inhalation* Inasmuch as the Ethyl Fluid in the pump was diluted with gasoline, one cannot be certain that actual Inhalation of tetraethyl lead occurred* It was pro bably slight and perhaps negligible, since apparently only fifteen minutes elapsed during the repair* The question!

lo case of acuto tetraethyl lead poisoning has been seen to persist with active symptoms or evidences of abnormal lead excretion through such a period. 5* The lead examinations reported by Dr.

Chemically, tetraethyl lead is simple, being produced from three raw mater- ?

Navy have had a considerable background of experience in using aviation gasoline containing 4.5 cc of the tetraethyl lead.

Phllp presented the economic justification for Increasing the permissible limit of tetraethyl lead to 4 mis. per U.S. gallon.

Navy have had a considerable background of experience in using aviation gasoline containing 4.5 cc of the tetraethyl lead.

My supply of reprints of this article Is exhausted* We have other clinical data on tetraethyl lead poisoning which has not been published bub which I hope to get into print some time in the near future* The article on "The Behavior of Lead in the Animal Organism II Tetraethyl Lead", and the series of articles "On the Normal Absorption and Excretion of Lead" are among the last of my copies.

My supply of reprints of this article Is exhausted* We have other clinical data on tetraethyl lead poisoning which has not been published bub which I hope to get into print some time in the near future* The article on "The Behavior of Lead in the Animal Organism II Tetraethyl Lead", and the series of articles "On the Normal Absorption and Excretion of Lead" are among the last of my copies.

Analysis Number - 53A>"951 Per Cent Lead as Lead Tetraethyl - 0.01 Per Cent Lead as Triethyl Lead Halides - 0.06 .