A uniformly favourable impression of our company1s willingness to inform the authorities in advance of the proposed increase in tetraethyl lead seemed to be the feeling of the various men.

Kehoe ' Laboratory of Applied'Physiology University of Cincinnati Eden Avenue Cincinnati, Ohio Dear Dr- Kehoe: This r/ill acknowledge receipt of your letter of July 25, 194-0, in which you ask for a date which is mutually convenient to discuss certain matters per taining to tetraethyl lead.

: City for some years and that he had done some of the autopsy and subsequent investigations in connection with the Bayway poisoning* I have no knowledgeoJMaovMpr* Korrls and Gattlor obtained information about the ^flH|H|case* However, ny best guess is that something in tnn^srtuatlon load them to believe that this case was similar to the Bayway poisoning and that they might find tetraethyl lead in the tissues as they did in certain of the Bayway cases* I have no reason to believe that either of those gentlemen is other than an able and honest Investigator* Consequently, I do not believe that you need to have any fear of their findings in this case* I have not heard from Dr.

Leake, surgeon in charge of the office of Tetraethyl Lead Investigation, of the Public Health Service at Washing ton, D.

(SFA) 32. sulfuric acid (spent)(SAC) 33. tetraethyl lead (TEL) 34. toluene (TOL) 35. undecanol (UND) 36. vinyl acetate (VAN) 37. vinyl chloride (VCM) 38. xylene (XLM, XLO, XLP) 39. zinc chloride (ZCL) Abbreviation assigned by Battelle.

` According to the information I have, their capacity for making tetraethyl lead solution is 360,000 pounds per day.

I am sending you, for whatever use it may be to memorandum prepared some time ago by my associa a consequence of our experience, in dealing with tetraethyl lead poisoning.

Some substances require protection against not only damage to the respiratory system but also systemic mpuy through die skm All substances should be investi gated to learn whether this double hazard is involved Some common substances which are hazardous through both the respiratory system and the skm are Amlme Carbon disulfide Cresol (cresylic acid) Dichloroethylene-1,1 Decalm (decahydronaphthalene) Diethylene oxide (dioxane-1,4) Disthylphthalate Dimethylanihne Duutrobenzene Duutrochlorobenzene Hydrogen cyanide (hydrocyanic acid) Iodoform Lead tetraethyl Mercury and its compounds Nicotine Nitrobenzene Nitroglycerine Organic phosphate insecticides Phenyl hydrazine Tetrahn (tetrahydronaphthalene) 36-21

The problem is of great interest to us from the point of view of the possible absorption of small amounts of tetraethyl lead from gasoline residues into the walls of the hose and we will naturally be very much interest ed in testing any hose of improved resistance which you may develop.

From a hygienic point of view we would favor the use of smaller volumes of gasoline than are now used, since less air, saturated with tetraethyl lead vapor will be displaced (present quantity about 9 cubic feet). 3:.nee the Manufacturing Department washes drums quite elaborately prior to repainting and refilling, I can see no 0 ictions from their end, but would suggest that after you have studied this thing, you communicate with Charlie Y/assernan and get his reaction to the introduction of this type of standpipe.

Taylor a ddr ess New York Changes in the Regulations for the Sale and Distribution of Gasoline Containing Tetraethyl Lead as Approved from Time to Time up to June, 194-6 date June 11, I94.6 In accordance with your letter of May 9, we have checked the draft of your proposed regulations.

., relative case, I looked up the matter of Dr, Dorris and Dr, er, remembering too lato to coint out to you h Ino 3 had been medical examiner in Cow York City- for some years and that he had done some of the autopsy and subsequent Investigations in connection with"tho Bayway poisoning, I have no knowledgeo ^ h m ^ D r , Dorris and Oattlor obtained information about the f f l H | | c a s @ , However, ny best guess is that something in th^sTtuatlon load them to believe that this case was similar to tho Bayway poisoning and that they might find tetraethyl lead in the tissues as they did in certain of the Bayway cases, I have no reason to believe that either of those gentlemen is other than an able and honest investigator.

Fron a hygienic point of view we would favor the use of smaller volumes of gasoline than are now used, since less air, saturated with tetraethyl lead vapor will be displaced (present quantity about 9 cubic feet).

Obviously, you cculd get the handlers of gasoline to testify that they have no knowledge of any such thing as any special toxicity imparted to gasoline through the addition cf this small quantity of tetraethyl lead.

Various small tetraethyl, lead manufacturing activities have developed in various parts of the country and with the expiration of the Ethyl patents which will occur reasonably soon, there will, of course, be no obstacle, except the economic one, to an increase In these enter prises.