AR226 3278 60 DR UNOACK-LABORATORIUM FOR ANGEWANDTE BIOLOGIE Earthworm (Eisenia fetida), Acute Toxicity Test in Artificial Soil ac. to OECD Guideline 207forTesting of Chemicals.

Blowing agent emissions from SPF products manufacturing /spraying use phase (0,75%/year) - source: IPPC over 20 y over 25 y over 30 y over 40 y over 50 y 10% 0.860 0.828 0.798 0.740 0.686 EoL of the building/ dismantling-demolition 1.50% remaining F Gas in the waste foam before recycling / landfilling / incineration (which would also involve more emissions from shredding) 75.92% 60.27% use phase 1% - source: F Gas Reg Recast EoL of the building/dismantling-demolition 10% 1% 1.5% 87.50% remaining F Gas in the waste foam before recycling / landfilling / incineration (which would also involve more emissions from shredding) 20y and 10% loss during spraying Emissions during EoL pathway of the waste foam: the % of BAs getting off when the SPF is taken off from the building seems to be at 1% if dices and large pieces are ending up in the waste collection bin 50y and 10% loss during spraying dismantling-demolition 50y and 10% loss during spraying 0in%lafnrodmfilliinncginsietreastieomni(ssFioGnassaarreeeditehsetrrocyaepdtuinremdubnyicaipwaal sstoeligdaws arestceovinecriynerators) system or then transformed in presence of other chemicals/gas to non GHG subtances

Attachment 4 Need a huge time to phase-out PFAS used for printers EVEN IF the substitute material of PFAS is available in the future The substitute materials instead of PFAS to fulfil for many of necessary functions required in printing process is not available yet.

PROTOCOL 418-008: COMBINED ORAL (GAVAGE) FERTII,11'Y, DEVELOPMENTAL PFOS IN RATS (SPONSOR'S STUDY NUMBER: 6295.9) AND PF.RINATAt,/ POSTNATAL REPRODUCTION TOXICITY TABLE E20 (PAGE 1): I.ITTER OBSERVATIONS (NATURAI.1,Y DELIVERED PUPS) - ST)MMARY F2 GENERATION LITTERS ----------------- - --- ...................... ------------------- MATERNAL DOSAGE GROUP 1 11 HATERNAI, DOSAGE (MG/KG/I)AY) 0 (VEHICI,E) 0.1 ----------------------- ----------------------------------------------- DELIVERED LITTERS WITH ONE OR MORE LIVEHORN PUPS N 22 21 ......-----------------------------111 0.4 -------------------------------------- 24 PUPS DELIVERED ITOTAL) N MEAN+S.D. 316 14.4 + 3.5 325 15.5 + 2.5 357 14.9 + 2.6 LIVEBORN MEAN+S.D.

12456789 5 98 8695 979 859 95 56!

Technische Information Dy neo nTM PFA 6502T Z Fluorthermoplast M erk male Breites TemperaturVerarbeitungsfenster Verbesserte Entformungseigenschaften Verbesserte Spannungsribestndigkeit Glatte Oberflchen Hohe Transparenz Bevorzugte Verarbeitungsmethoden: Transfermolding und Extrusion T y pisc he Eigensc haf ten* Eigensc haf ten Dichte Schmelzpunkt MFI (372 C/5 kg) LOI T estmetho de DIN EN ISO 12086 DIN EN ISO 12086 DIN EN ISO 1133 ASTM D2863 Einheit g/cm3 C g/10 min % W ert 2,15 310 2 > 95 M ec hanisc he Eigensc haf ten an gesinterten Fo rmk rpern* Hrte ASTM D2240/ISO 868 60 Shore D Reifestigkeit DIN EN ISO 527-1 MPa 30 Reidehnung DIN EN ISO 527-1 % 380 Biege E-Modul ASTM D790 MPa 550 * Mittelwerte A llgemein DyneonTM PFA 6502T Z Fluorthermoplast, ist ein neuer Fluorthermoplast, der sich durch ein stark verbreitertes Verarbeitungsfenster auszeichnet.

Pmraottteecrts.what 3MTM NovecTM 1230 Fire Protection Fluid You're not just safeguarding people, buildings, equipment and operations, you're helping preserve the world we live in.

Summary Report 104-Week DietaryChronicToxicityand CarcinogenicitSytudy withPerfluorooctanSeulfonicAcid Potassium Salt(PFOS: T-6295) inRats PREPARED FOR: 3M COVANCE STUDY NUMMER: 6329-183 SUMMARY REPORT -WEEK 53 104Week DietarTyoxiciatnydCarcinogeniSctiutdyywithPerfluorooctane SulfonicAcid PotassiumSalt(PFOS; T-6295)inRats Timeline Covance 6329-183: In-lifsetartdate:April20, 1998 Week 53 completed:April25, 1999 Introduction The purposeofthisstudyisto assessthechronictoxicitaynd carcinogeniciotfythetest materialT,-6295 (PerfluorooctanseulfoniaccidpotassiumsaltP,FOS), when administered inthedietto ratsforatleast104 weeks.

Comments on Annex XV Restriction Report on Per- and polyfluoroalkyl substances (PFAS) 1.

ARRAG _ S416 - 20 Pe 000212 ARBRE - DHE .

Mintel GNPD Global Market: 204.818 Total amount of cosmetic products launched during last 5 years (within Beauty & Personal Care, without cleansers and nail enamel removers) 14.428 dem, containing "peptides" (Mintel Chemical Class group) 60% 8.657 dem, containing n-peptide-X INCI names (obtained through SPPS) 4,23% from total cosmetic products launched EU Market: 81.992 Total amount of cosmetic products launched during last 5 years (within Beauty & Personal Care, without cleansers and nail enamel removers) 5.745 dem, containing "peptides" (Mintel Chemical Class group) 60% 3.447 dem, containing n-peptide-X INCI names (obtained through SPPS) 4,20% from total cosmetic products launched ure

Ee -------- ~{m !

3rd submission - Comment on Proposed Restriction of PFAS Conference of Fluoro-Chemical Product Japan (FCJ) (Regarding the requirement to provide information in paragraph 7) In paragraph 7 of the proposed restriction, the information requirement for derogated applications in paragraph 5 and 6 states that article manufacturers and importers need to provide information related to the identification of substances placed on the market.

Auswirkungen einer Beschrnkung von Fluorpolymeren auf Handelsunternehmen und ihre Rolle in der Lieferkette ITS GmbH Stellungnahme zum BESCHRNKUNGSBERICHT ANHANG XV ber per- und polyfluorierte Alkylsubstanzen (PFAS) Zusammenfassung ITS GmbH versteht sich als kompetenter Partner zur Optimierung der Beschaffungsprozesse ihrer Kunden.

What we knew at the start Microplastics: Typically refer to solid particles (including fibres) made from synthetic polymers < 5mm in size Secondary MPs formed as larger pieces of `plastic' degrade/abrade Litter (SUPs, fishing gear, bottles, nurdles), synthetic clothing, tyre abrasion Primary MPs in various types of products added for achieving specific functionalities Beads, encapsulates, flakes, powders, crumbs 2 Sector-specific impact assessment Quantities and emissions in scope Alternatives and costs to develop them Other costs (e.g. foreseeable profit losses) Cost/effectiveness ratios (comparing substitution cost vs emissions) Sectors very diverse in terms of substitutability Different restriction proposals for sectors (ban, conditional derogations, mandatory instructions, mandatory reporting, grace periods) 5 Overall proportionality argumentation Use volumes and emissions in scope Effectiveness of emission abatement Marginal abatement cost curve Theoretical considerations 8 Marginal abatement cost curve 10 Further theoretical arguments Option value theory `first act, then learn' rather than `first learn, then act' Builds on the justified assumption that emissions are irreversible we will learn a great deal more about the harmfulness of MPs in the environment in the near term future Option value is net value resulting from the avoidance of irreversible emissions conditional on learning about the actual harmfulness of MPs 11 Conclusions Clear definition of MPs has helped us Early identification of sectors/uses has helped us Providing an analysis of restricting infill material during opinion making was tedious Focus on C/E has made impact assessment comparable across uses Benefits hard to quantify, discussed qualitatively Good to have theoretical arguments that underpin proposed actions but did not get a lot of attention 12