clour distinction rust ha drarm, :<n tea hbcim by the vmeentr^dieted evidence, between tetraethyl i eo-j non leaded noth ice.

That is to cay, there are certain locations in which men tend to be exposed fairly frequently to the vapors of tetraethyl lead.

The dangers here are very real, '"e have made a very elaborate study of this pro blem, 'which I can not go into in detail in this letter, but under certain circumstances, which are not predictable, considera ble quantities of decomposition products of tetraethyl lead, to gether with small quantities of tetraethyl lead itself, accumu late under the water layer In the bottom of these* tanks.

Thoso with the results of analysis, are listed below* and are compared with the average results obtained by this laboratory on normal parsons* as well as those obtained in a previous fatal case of tetraethyl lead poisoning.

The dangers here are very real, '"e have made a very elaborate study of this pro blem, 'which I can not go into in detail in this letter, but under certain circumstances, which are not predictable, considera ble quantities of decomposition products of tetraethyl lead, to gether with small quantities of tetraethyl lead itself, accumu late under the water layer In the bottom of these* tanks.

I believe that it is the same there* The complication that I speak of arises from the fact that the lead concentration in the blood following the absorption of tetraethyl lead# is quite different than with which would obtain if the.same quantity of inorganic lead were absorbed in the same time In other words the relationship between lead concentration in the blood and that in the urine is quite different When tetraethyl lead is being absorbed.

TETRAETHYL LEAD, "ETHYL" ANTI-KNOCK COMPOUNDS OR SOLUTIONS OF THESE PRODUCTS THE ASSOCIATED ETHYL COMPANY LIMITED, LONDON Memorandum on the Decontamination of Materials which have come in contact with Tetraethyl Lead, "ETHYL" Anti-Knock Compounds or Solutions of these Products INTRODUCTION t h e d is p o s a l of spilled tetraethyl lead or "Ethyl" anti-knock compound is a serious problem which involves immediate hazard to those who undertake the task of disposal, and to others who may be near at hand.

A further decomposition takes place as shown by the fact that within about 1^ days of the administration of a sublethal dose the distribution of lead in the tissue corresponds to that of water soluble lead compounds rather than to that characteristic of tetraethyl lead.

Our observations in this country have demonstrated that this is the case among our workmen at this job, and unless there is some serious defect in the procedure of tetraethyl/lead, is quite different than with which would obtain if the.same quantity of inorganic lead were absorbed in the same time In other words the relationship between lead concentration in the blood and that in the urine is quite different When tetraethyl lead is being absorbed.

Ilei3 because of the presence of Ethyl fluid or tetraethyl lead been responsible for the poisoning or injury of any human being, and our experience definitely leads us to the opin ion that this amount cf dilution in gasoline has no more affect by inhalation or absorption than has that of the general run-of-mine gasoline.

At present, however, I insist upon having samples of blood for analysis in all cases of childhood lead poisoning, and in all cases of lead poisoning in the adult, except those rare cases of tetraethyl lead poisoning which occur under highly unusual or accidental cir cumstances (when tetraethyl lead is absorbed, the blood level increases little or none, apparently because the intermediate compounds resultant upon the de- ' composition of the molecule in the tissues are r.ot capable of combining with the component of the crytlirocyte that is involved when inorganic lead compounds are absorbed).

We have made a very elaborate study of this pro blem, which I can not go into in detail in this letter, but under certain circumstances, which are not predictable, considra ble quantities of decomposition products of tetraethyl lead, to gether with snail quantities of tetraethyl lead itself, accumu late under the water layer in the bottom of these tanks.

Do we have sufficient capacity to take care of our customers for a period of several years in the event that the metallic lead situa tion would improve and tetraethyl lead would be on an unrestricted basis of distribution?

I trust you will not have the opportunity of seeing any cases of tetraethyl lead poisoning.

I trust you will not have the opportunity of seeing any cases of tetraethyl lead poisoning.