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SUMMARY SJg was employed by Orange State Oil Company in maintenance work, and in this capacity, he, 1 th othorn, was engaged in asking certain alterations in pipe line connections and In cleaning out the corresponding gasoline storage tanka at a number of terminals of Orange State Oil Company. During the period of December 6th to 12fch ha was at Tampa and at tala point a large storage tank was cleaned. This tank, on subsequent investigation, was found to have bean used for mixing leaded gasoline in January of cl had not been cleaned since* The mixing operations consisted in th introduction of anti knock Fluid in to a gasoline stream entertrig the tank, instead of filling the tank with gasoline siready mixed with Fluid at a regular- mixing point. Under- these conditions of mixing, it may happen that th Fluid separates out, to soma degrees and lioa under the water layer at the bottom of a tack for an Indefinite period, or until the tank is cleaned out* Gone degree of auoh separation evidently occurred in this case, for the examination of some of the sludge removed in cleaning (obtained subsequently from a pit in which it had dried out almost entirely) disclosed th presence of 0.005$ of organic load, and 1.6$ total lead. The tank which wpa cleaned, and from which this sludge sample was derived, was the only one at this site which had been used for tile direct mixing, of leaded gasoline. It, therefore, can be convicted of giving rise to the serious lead exposure subsequently revealed in the illness KF 002105 N24470 fro Peoember 1st onward shows that no other opportunities for significant occupational load exposure occurred. Borne days after completing the job of cleaning the above tank* bee&ss ill* and to abbreviate the clinical history* which is available In part in his hospital record* his illness developed In severity and followed the characteristic course of a fatal case of organic lead Intoxication. The necropsy findings were compatible with the clinical diagnosis above* and in fact* except for certain unrelated chronic lesions* resembled those described in certain previous fatal cases of lead poisoning. The terminal broncho pneumonia* for example has been described In such oases before* (Sorrl3 and Gettler, J.A.M.A. 8 5 1 8l8, (1 9 2 5 )* Certain tissues were available for analysis and wore sent by Dr. L. Y. Byrenforfch* Pathologist at St. Luke's Hospital of Jacksonvilla to the Kettering Laboratory of Applied Phyaio'.ogy at the College of %dlcine of the University of Cincinn-ti. Thoso with the results of analysis, are listed below* and are compared with the average results obtained by this laboratory on normal parsons* as well as those obtained in a previous fatal case of tetraethyl lead poisoning. Description of Ti'a'suo Lead in Milligrams pr 100 Grass Hubbard Previous Case Morm&l Persona Liver Kidney Brain Lung 2.0b o . 6h 1.08 o.l*5 2.1*0 1 .3 1 0.B5 o.U8 0.130 0.02? 0.013 0.028 K" 0021058 3 Certain possibi ilties for the chance contamination of th tl33n3 before receipt at this laboratory -are Investi gated* Samples of the embalming fluids used for.embalming the body before the necropsy, and a sssapl of the formalin in which the tl33ues had been preserved by the pathologist, were analysed for their lead content. Only traces of load were found in those material* Also the containers used by. the pathologist for the preservation of the tissues were examined and found satisfactory* The above analyses m y be accepted, therefore, as evidence of the facta as to the lead content of the tissues of Hubbard at the time of his death* In summary, the source and significance of the lead exposure of the deceased have been demonstrated, the onset and clinical course of his Illness ware typical of acute organic load poisoning as previously seen and described, In medical literature ( K e f a o e , 85* 108, (1925) I Machlo, J.A.if.A* 105* 578, (1935)}* the necropsy findings were compatible with the diagnosis of tetraethyl load poisoning, and the analytical results obtained on the tissues have revealod the px*osence of quantities of load sufficient to cause death. Signed* Robert A* Kehoe, H*D# Director Kettering Laboratory of Applied Physiology College of Medicine, Kdon Aye., Cincinnati, Ohio Kf 0021059