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Integrated Environmental Assessment and Management -- Volume 14, Number 3--pp. 316-334 316 Received: 26 September 2017 Returned for Revision: 16 January 2018 Accepted: 30 January 2018 Critical Review A Critical Review of the Application of Polymer of Low Concern and Regulatory Criteria to Fluoropolymers Barbara J Henry,*t Joseph P Carlin, t Jon A Hammerschmidt, f Robert C Buck,: L Heidelore Fiedler, Jennifer Seed,// and Oscar Hernandez# tWL Gore & Associates, Elkton, Maryland, USA tChemours Company, Wilmington, Delaware, USA MTM Research Centre School of Science and Technology, Orebro University, Orebro, Sweden //Risk Assessment Consultant, Alexandria, Virginia, USA #Bergeson & Campbell, Washington, DC, USA William Buxton, I ABSTRACT Per- and polyfluoroalkyl substances (PFAS) are a group of fluorinated substances that are in the focus of researchers and regulators due to widespread presence in the environment and biota, including humans, of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA).

ROBECCHI Lavorazioni Plastiche IIP UNI EN ISO 9001:2015 CERT N.245 Date: 09 September 2021 ROBECCHI ARTICOLI TECNICI S.r.I. - Via Tribolina, 25 24064 GRUMELLO DEL MONTE (BG) - ITALY Reg.

* * * THIS REPORT MAY CONTAIN CONFIDENTIAL INFORMATION * * * Authorisation Details (All Releases) Qualification Notes Authorisation No: BU5453IY Operator: AGC Chemicals Europe Limited Local Authority: WYRE BOROUGH COUNCIL Start Date: 19/07/2017 Type: IPPC End Date: 01 March 2023 Substance name Ammonia Arsenic Cadmium Carbon dioxide Carbon dioxide - 'thermal' Carbon monoxide PI-1v10 Medium Year Reporting threshold Air 2013 1000 kg 2012 1000 kg 2011 1000 kg 2010 1000 kg 2009 1000 kg 2008 1000 kg 2007 1000 kg Controlled Waters 2020 5 kg 2019 5 kg Controlled Waters 2021 1 kg 2019 1 kg Air 2015 1.0E+7 kg 2014 1.0E+7 kg 2013 1.0E+7 kg 2012 1.0E+7 kg 2011 1.0E+7 kg 2010 1.0E+7 kg 2009 1.0E+7 kg Air 2008 1.0E+7 kg 2007 1.0E+7 kg Air 2020 100000 kg 2019 100000 kg 2018 100000 kg 2017 100000 kg 2016 100000 kg BU5453IY: AGC Chemicals Europe Limited Limit Actual BRT BRT BRT BRT BRT BRT BRT BRT 6.05 kg 2.8 kg 3.25 kg 18212.1 t 13218 t 12404 t 12615 t 13195 t BRT BRT 12470 t 10569 t BRT 7.566 t 9.86 t BRT BRT Unauth 4.406 kg 2.399 t 12.924 kg Check CinC Page 1 * * * THIS REPORT MAY CONTAIN CONFIDENTIAL INFORMATION * * * Substance name Chromium Copper Ethylene (Ethene) Fluorides - as F Fluorine and inorganic fluorine compounds - as HF Hydrochlorofluorocarbons (HCFCs) PI-1v10 Medium Year Reporting threshold 2013 100000 kg 2012 100000 kg 2009 100000 kg 2008 100000 kg 2007 100000 kg Controlled Waters 2020 2019 20 kg 20 kg Controlled Waters 2020 2019 20 kg 20 kg Air 2011 1000 kg 2010 1000 kg 2009 1000 kg 2008 1000 kg 2007 1000 kg Controlled Waters 2019 2018 2016 2015 2014 2013 2012 2011 2010 2009 2000 kg 2000 kg 2000 kg 2000 kg 2000 kg 2000 kg 2000 kg 2000 kg 2000 kg 2000 kg Air 2020 1000 kg 2019 1000 kg 2013 1000 kg 2012 1000 kg 2009 1000 kg 2008 1000 kg 2007 1000 kg Air 2022 1 kg 2021 1 kg 2019 1 kg 2018 1 kg BU5453IY: AGC Chemicals Europe Limited Limit Actual BRT BRT BRT BRT BRT BRT 8.73 kg BRT 4.93 kg BRT BRT BRT BRT BRT 2002 kg 3341 kg 1391.47 kg BRT BRT BRT 2133 kg 2572 kg 2527 kg BRT BRT 61 kg BRT BRT BRT BRT BRT 2.576 t 2.64 t 2.16 t 1.86 t Unauth 6.916 kg 3.276 kg 140 kg Check CinC Page 2 Substance name Hydrofluorocarbons (HFCs) Lead Mercury Mercury PI-1v10 * * * THIS REPORT MAY CONTAIN CONFIDENTIAL INFORMATION * * * Medium Year Reporting threshold 2017 1 kg 2016 1 kg 2015 1 kg 2014 1 kg 2013 1 kg 2012 1 kg 2011 1 kg 2010 1 kg 2009 1 kg 2008 1 kg 2007 1 kg Air 2022 100 kg 2021 100 kg 2019 100 kg 2018 100 kg 2017 100 kg 2016 100 kg 2015 100 kg 2014 100 kg 2013 100 kg 2012 100 kg 2011 100 kg 2010 100 kg 2009 100 kg 2008 100 kg 2007 100 kg Controlled Waters 2020 2019 20 kg 20 kg Air 2017 1 kg Controlled Waters 2022 2019 2018 2016 2015 2014 2013 0.1 kg 0.1 kg 0.1 kg 0.1 kg 0.1 kg 0.1 kg 0.1 kg BU5453IY: AGC Chemicals Europe Limited Limit Actual 2.037 t 1.966 t 2.319 t 2.663 t 3.142 t 2.52 t 2.614 t 2.52 t 2.29 t 2.27 t 8.6 t 2.226 t 1.26 t 0.711 t 1.037 t 1.532 t 1.687 t 2.912 t 2.541 t 2.143 t 1.724 t 2.24 t 1.355 t 0.68 t 0.905 t 1.5 t BRT 5.55 kg 0.114 kg 1.35 kg 0.126 kg 0.127 kg 0.107 kg BRT BRT BRT Unauth 4.5 t 33.77 kg 5.56 kg Check Check 3 Check 4 CinC Page 3 Substance name Nickel Nitrogen oxides (NO and NO2) as NO2 Nitrous oxide Octylphenol ethoxylates Octylphenol ethoxylates Octylphenols and octylphenol ethoxylates Perfluorocarbons (PFCs) PI-1v10 * * * THIS REPORT MAY CONTAIN CONFIDENTIAL INFORMATION * * * Medium Controlled Waters Air Air Controlled Waters Wastewater Controlled Waters Air Year 2012 2011 2010 2009 2008 2007 2020 2019 2020 2019 2008 2007 2013 2012 2011 2010 2009 2011 2010 2009 2008 2007 2007 2020 2019 2018 2015 2014 2013 2012 2022 2021 2019 2018 Reporting threshold 0.1 kg 0.1 kg 0.1 kg 0.1 kg 0.1 kg 0.1 kg 20 kg 20 kg 100000 kg 100000 kg 100000 kg 100000 kg 10000 kg 10000 kg 10000 kg 10000 kg 10000 kg 1 kg 1 kg 1 kg 1 kg 1 kg 1 kg 1 kg 1 kg 1 kg 1 kg 1 kg 1 kg 1 kg 10 kg 10 kg 10 kg 10 kg Limit Actual BRT BRT BRT BRT BRT BRT BRT 5.24 kg BRT 1282 kg BRT BRT BRT BRT BRT BRT BRT 1.588 kg 3.081 kg 235.53 kg 390.66 kg 0.45 t 453 kg BRT 0.228 kg 1.038 kg 0.00006 kg 0.5 kg 1.224 kg 1.013 kg 4.106 t 9.73 t 7.78 t 13.48 t BU5453IY: AGC Chemicals Europe Limited Unauth 3.574 kg 652 kg 0.035 kg Check Check 2 CinC Page 4 * * * THIS REPORT MAY CONTAIN CONFIDENTIAL INFORMATION * * * Substance name Medium Year Reporting threshold 2017 10 kg 2016 10 kg 2015 10 kg 2014 10 kg 2013 10 kg 2012 10 kg 2011 10 kg 2010 10 kg 2009 10 kg 2008 10 kg 2007 10 kg Sulphur oxides (SO2 and SO3) as SO2 Air 2020 100000 kg 2019 100000 kg Tetrafluoroethylene Air 2011 10 kg 2010 10 kg 2009 10 kg 2008 10 kg 2007 10 kg Total organic carbon (TOC) Controlled Waters 2022 2021 2019 2018 2015 2014 2013 2012 2011 2010 2009 2008 2007 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg 50000 kg Waste transfer 02 01 10 Waste metal 2015 5t R13 Storage of wastes pending any of the operations numbered R1-R12 (excl temporary storage at site where it is produced) Waste transfer 05 01 04 Acid alkyl sludges 2009 n/a D15 Storage pending any of the operations numbered D1-D14 (excl temporary storage at site where it is PI-1v10 BU5453IY: AGC Chemicals Europe Limited Limit Actual 17.267 t 16.26 t 23.7 t 9.25 t 14.3 t 11.77 t BRT BRT BRT BRT BRT BRT 3.3 kg 13.25 t 8.144 t 4.6 t 10.12 t 0.66 t 88454.46 kg 77944 kg 111291 kg 112038 kg 106934.805 kg 53684 kg 55191 kg BRT BRT BRT BRT BRT 20.9 t 14.143 t 6t Unauth 678 kg 0.6 kg 0.236 t 492 kg Check CinC Page 5 * * * THIS REPORT MAY CONTAIN CONFIDENTIAL INFORMATION * * * Substance name produced) Medium Year Reporting threshold Waste transfer 05 01 11 Wastes from cleaning of fuels with bases 2015 n/a D15 Storage pending any of the operations numbered D1-D14 (excl temporary storage at site where it is produced) Waste transfer 06 01 01 Sulphuric acid and sulphurous acid 2022 n/a D15 Storage pending any of the operations numbered D1-D14 (excl temporary storage at site where it is produced) 2021 n/a 2019 n/a 2018 n/a 2017 n/a 2016 n/a 2015 n/a 2013 n/a 2012 n/a 2009 n/a Waste transfer 06 01 01 Sulphuric acid and sulphurous acid 2022 n/a D9 Physio-chemical treatment not specified elsewhere resulting in materials which are discarded by a D1-D12 activity 2021 n/a 2020 n/a 2019 n/a 2018 n/a 2016 n/a 2012 n/a 2010 n/a Waste transfer 06 01 01 Sulphuric acid and sulphurous acid 2022 n/a R13 Storage of wastes pending any of the operations numbered R1-R12 (excl temporary storage at site where it is produced) 2020 n/a 2019 n/a 2018 n/a 2017 n/a Waste transfer 06 01 02 Hydrochloric acid 2015 n/a D15 Storage pending any of the operations numbered D1-D14 (excl temporary storage at site where it is produced) 2013 n/a PI-1v10 BU5453IY: AGC Chemicals Europe Limited Limit Actual 6t 17.8 t 0.45 t 2t 3.01 t 0.336 t 4.59 t 7t 6t 35 t 0.025 t 3.8 t 5.946 t 12.135 t 15.029 t 8.928 t 1.53 t 21.826 t 42 t 0.06 t 6.945 t 2.022 t 1.2 t 2.005 t 0.9 t 1t Unauth Check Check 3 Check 2 CinC Page 6 * * * THIS REPORT MAY CONTAIN CONFIDENTIAL INFORMATION * * * Substance name Medium Year Reporting threshold Waste transfer 06 01 02 Hydrochloric acid 2022 n/a D9 Physio-chemical treatment not specified elsewhere resulting in materials which are discarded by a D1-D12 activity 2020 n/a 2019 n/a Waste transfer 06 01 02 Hydrochloric acid 2016 n/a R13 Storage of wastes pending any of the operations numbered R1-R12 (excl temporary storage at site where it is produced) Waste transfer 06 01 03 Hydrofluoric acid D10 Incineration on Land 2021 n/a Waste transfer 06 01 03 Hydrofluoric acid 2018 n/a D15 Storage pending any of the operations numbered D1-D14 (excl temporary storage at site where it is produced) 2017 n/a 2013 n/a Waste transfer 06 01 03 Hydrofluoric acid 2017 n/a D5 Specially engineered landfill (eg placement into discrete cells which are lined and capped) Waste transfer 06 01 03 Hydrofluoric acid 2022 n/a D9 Physio-chemical treatment not specified elsewhere resulting in materials which are discarded by a D1-D12 activity 2021 n/a 2020 n/a 2019 n/a 2018 n/a 2016 n/a 2015 n/a 2014 n/a Waste transfer 06 01 03 Hydrofluoric acid 2022 n/a R13 Storage of wastes pending any of the operations numbered R1-R12 (excl temporary storage at site where it is produced) Waste transfer 06 01 04 Phosphoric and phosphorous acid 2022 n/a R13 Storage of wastes pending any of the operations numbered R1-R12 (excl temporary storage at site where it is produced) Waste transfer 06 01 05 Nitric acid and nitrous acid 2016 n/a D15 Storage pending any of the operations numbered D1-D14 (excl temporary storage at site where it is PI-1v10 BU5453IY: AGC Chemicals Europe Limited Limit Actual 0.06 t 0.8 t 0.002 t 0.1 t 0.009 t 0.035 t 0.01 t 0.03 t 0.185 t 0.57 t 0.129 t 0.096 t 0.112 t 0.106 t 0.015 t 0.045 t 0.0875 t 0.02 t 0.001 t 0.007 t Unauth Check Check 3 CinC Page 7 * * * THIS REPORT MAY CONTAIN CONFIDENTIAL INFORMATION * * * Substance name Medium Year produced) Waste transfer 06 01 06 Other acids 2011 D10 Incineration on Land Waste transfer 06 01 06 Other acids 2019 D15 Storage pending any of the operations numbered D1-D14 (excl temporary storage at site where it is produced) 2017 2016 2014 2013 Waste transfer 06 01 06 Other acids 2017 D5 Specially engineered landfill (eg placement into discrete cells which are lined and capped) Waste transfer 06 01 06 Other acids 2022 D9 Physio-chemical treatment not specified elsewhere resulting in materials which are discarded by a D1-D12 activity 2021 2020 2019 2016 Waste transfer 06 01 06 Other acids 2019 R13 Storage of wastes pending an

ARTICLE pubs.acs.org/est Atmospheric Degradation of Perfluoro-2-methyl-3-pentanone: Photolysis, Hydrolysis and Hydration Derek A.

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ST-310 ToxDocs 10-195 TOXICOLOGY ASSESSMENT AND COMPLIANCE ASSURANCE GROUP 3M COMPANY 10-195: ORAL STUDY OF MTDID 208 AND MTDID 1004 IN MALE RATS FINAL REPORT ToxDocs Study Number 10-195 Test Material MTDID 208 Lot Number(s) MTDID 1004 217 (MTDID 208) Strategic Tox Lab Study Number | 332 (MTDID ST-310 1004) Other Identification Number(s) | K'PFOS (MTDID 208) NH;"PFOA (MTDID 1004) 19F/TH-NMR GID Number Analytical Report | See Appendices 1 & 2 for Certificate of Analysis Study Director Jill Hart, AAS, LATg Laboratory Administrator Principle Investigator: (Study Monitor) John Butenhoff, Ph.D, DABT, CIH Corporate Scientist Testing Facility Tn-Life Start Date 3M Strategic Toxicology Laboratory 3M Center, Bldg 270, room SB314 Saint Paul, MN 55144 August 4, 2010 Tn-Life Termination Date October 4, 2010 Tof14 ST-310 "ToxDocs 10-195 TOXICOLOGY ASSESSMENT AND COMPLIANCE ASSURANCE GROUP 3M COMPANY 10-195: ORAL STUDY OF MTDID 208 AND MTDID 1004 IN MALE RATS Compliance Statement and Signature Page `This study was conducted to regulatory guidelines.

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No.: EG151231019V01MVer.2.0 Test Report Date: Mar. 14, 2016 Applicant Address : Changzhou XCF Polymer Materials Co., Ltd. : No.15 Dongcheng Road, Dingyan Town, Changzhou, China Page 1 of 3 Sample Name Quantity Model Lot No.

JOURNAL OF GEOPHYSICAL RESEARCH, VOL. 116, D24307, doi:10.1029/2011JD016518, 2011 OH reaction rate constant, IR absorption spectrum, ozone depletion potentials and global warming potentials of 2-bromo-3,3,3-trifluoropropene Kenneth O.

Integrated Environmental Assessment and Management -- Volume 14, Number 3--pp. 316-334 316 Received: 26 September 2017 Returned for Revision: 16 January 2018 Accepted: 30 January 2018 Critical Review A Critical Review of the Application of Polymer of Low Concern and Regulatory Criteria to Fluoropolymers Barbara J Henry,*t Joseph P Carlin,t Jon A Hammerschmickt Robert C Buck,..

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WOUND HEALING WITH FIFLOW AA In vivo confocal observations of acne scars reduction process with Fiflow AA Oxygen: a wound-healing advance Alain SAINTROND Jaana PRINTZ Marion NOUVET The Innovation Company, Dreux, France (2018) INTRODUCTION Acne vulgaris is the most common type of acne skin disease.

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