Weiss This control study evaluated the risk of epithelial ovarian cancer associated with various forms of powder application Cases included all genital exposure to women aged 20-79 years in three counties of western Washington who were diagnosed with borderline or invasive ovarian cancer from 1986 of eligible cases were interviewed A sample of similarly aged women who lived in thestehrcoouugnhti1e9s8i8de6nt4if.ie3d by random digit dialing served as controls The overall response among control women was 68.0 Information on powder application and other potential risk factors was ascertained during the person interview Overall ovarian cancer cases n = 313 were more likely than controls n = 422 to ever have used powder adjusted relative risk RR = 1.5 95 confidence interval CI 1.1-2.0 After adjustment for and other methods of genital powder application none vs. any an elevated relative risk of age ovarian cancer was noted only for women with a history of perineal dusting RR = 1.6 95 CI 1.1-2.3 or use of genital deodorant spray RR = 1.9 95 CI 1.1-3.1 These results offer support for the hypothesis raised by prior epidemiologic studies that powder exposure from perineal dusting contributes to the development of ovarian cancer and they suggest that use of genital deodorant sprays may do so as well Limitations of the present study include the fairly low proportion of eligible women who participated and the potential differential recall of powder usage Am J Epidemiol 459 65 ovarian neoplasms powders talc asoline a 111-14 ernational 1995 .

Weiss 1,2 This case-control study evaluated the risk of epithelial ovarian cancer associated with genital exposure to Wa^hin ?

Associations for RQ Adjustment American Fiber Manufacturers Association Chemical Manufacturers Association Cosmetic, Toiletry, and Fragrance Association, Inc.

Associations for RQ Adjustment American Fiber Manufacturers Association Chemical Manufacturers Association Cosmetic, Toiletry, and Fragrance Association, Inc National Paint and Coatings Association Society of the Plastics Industry, Inc September 1992 SL 066986 Vinyl Chiciride This is the latest article in a series which highlights the activities of the various CHEMSTAR Panels and Councils.

Associations for RQ Adjustment American Fiber Manufacturers Association Chemical Manufacturers Association Cosmetic, Toiletry, and Fragrance Association, Inc.

imttCY95% KSEMCl5% IESIABCN 65% BraCinDN 35% --iii .

Specific issue group activity began at the Association in 1972, when the Phosgene Panel was chartered.

Specific issue group activity began at the Association in 1972, when the Phosgene Panel was chartered.

In many ways they mirror the diverse focuses of the Chemical Manufacturers Association itself.

Both are closely woven into the fabric of the Association's activities.

The Panel main tains liaison with the Soap and Detergent Association on scientific and regulatory issues.

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Ito ih hypotheses ,ue com patible w ith the know n in le rn a iio n .il and 1eg10n.1l associations betw een ovarian [.m ie i risk and dietary tat icm sum ption.

ABD00003011 CANCER FACTS & FIGURES-1994 vAAAERICAN CANCER * SOCIETY E^.rr.c'ed nurber c; ne j ccnccr cc.'

CONSENT DECREE SUBSTANCE: Any matter relating to triaodium phosphate (a restriction re quired by a 1962 consent decree to which CMA is a party) SL 107281 CHEMICAL MANUFACTURERS ASSOCIATION Vinyl Chloride Panel Research Coordinators Record of Conference Call DATE: TIME: June 13, 1994 10:00 a.m.