Document bRaKe078oem1bYy9Qqa8QnGO

A Repoi The Year 1990-1991 CMA 030651 CHAIRMAN'S REMARKS CHEMSTAR Panels and Councils pro vide substantial benefits to our compa nies from comparatively modest invest ments of personnel and money. Whether conducting advocacy, sponsoring re search, holding workshops and sympo sia, or issuing publications, these organi zations play significant roles in improv ing the performance of our industry. Just as importantly, they continue to forge stronger bonds with companies and other industries in the US and abroad. Because of their many and diverse contributions, the Panels and Councils deserve our at tention and appreciation. The Panels and Councils are thoroughly integrated into the CMA framework. In concert with the Standing Committees they give the industry a comprehensive coverage, from the general to the specific, of issues vital to its economic viability. Our companies will continue to benefit from CHEMSTAR groups only if we place high priorities on awareness of their ac tivities, recognition of our employees' con tributions to their successes, and commit ment to active participation in their projects. Earnest W. Oeavenport, Jr. Eastman Chemical Company Chairman, CHEMSTAR Policy Committee PRESIDENT'S OVERVIEW Regulatory Affairs..................................... 35 Research.................................................... 37 Guidance................................................... 38 Management Services...............................39 Quick and versatile responses to mem bers' issues have always characterized CHEMSTAR Panels. Reflecting this re sponsiveness, Panels continue to grow in numberand focus. The Business Coun cils have taken on the same attributes as the Panels. Accordingly, the Councils already are growing vigorously in num ber, participants, and emphasis. Together the Panels and Councils form a strong complementary tool for addressing and solving critical concerns of discrete seg ments of the Association's membership. CHEMSTAR Councils and Panels are similar in the ways they operate. Both are closely woven into the fabric of the Association's activities. This integration brings them under the purview of vari ous industry initiatives, particularly Re sponsible Care* Representatives of CHEMSTAR groups have participated in Responsible Care* Code development and several Councils are preparing imple mentation aids in response to Codes. The activities ot the Panels and Councils fall into six broad categories: advocacy, research, education, communication, evaluation, and litigation. Although in the past the Panels concentrated on re search and advocacy, we now see educa tion, evaluation and communication in creasing in importance. Panel advocacy produced signifi cant successes this year, saving industry several million dollars in research and reporting costs. EPA eased regulations on air emissions based on persuasive arguments sup ported by data from a fugitive emissions study conducted by the Butadiene, Ethyl ene Oxide and Phosgene Panels. The Agency now cites this study as a bench mark for collection of emissions data on other chemicals. In response to com ments from the Fluoroalkenes Panel about lower tier tests conducted under a TSCA Section 4 test rule, EPA rescinded the requirements for additional tests on hexafluoropropene and vinyl fluoride which would have cost over $2 million. In addition, the Biocides Panel was suc cessful in opposing EPA's proposal for generic approval of data call-ins for FIFRA List A chemicals. The Agency must now get specific approval from OMB for each data call-in and solicit public comment before requiring costly data generation by the industry. Research is still a major activity of many Panels. During the past year, voluntary programs were com pleted by the Ethylene Glycol and Alky1phenols and Ethoxylates Panels. Because of successful results from tests sponsored by the Oleylamine Panel, additional test- CMA 030653 ing viill not be required bv EPA. In addition, the number ot joint research efforts with non-industrv groups is in creasing. The Acetone Panel is cospon soring a project with state agencies and industry associations to assess the effects ot volatile organic emissions on photo chemical ozone formation. In addition, the Hvdrazine Panel is exploring a ]oint proiect with the Air Force, the N'avy and NASA. Panels and Councils work to edu cate their members, workers, chemical industry executives, safety personnel, government of ficials, and the public. The Titanium Dioxide, Hydrogen Fluoride and Phenol Panels each hold regular information sharing sessions at which members dis cuss ways to improve the safe handling of these chemicals. A Product Approval Code of Practice for engine testing of candidate oils was developed by the Pe troleum Add itives Panel, and introduced ata recent workshop. "Questions of Qual ity ISO 9000 and the Chemical Industry" was published by theTotal Quality Coun cil to clarify issues in this important area tor company personnel. In addition, the Chlorinated Pool Chemicals Panel pre pared a bulletin and videotape on proper procedures for storing and handling pool chemicals to assist customers and first responders. Various types of communication activities are gaining in impor tance for Panels and Councils. Members of the Hvdroquinone Panel made presentations at Society of Toxicol ogy and Teratology Society meetings. In addition, the Total Quality Council achieved approval for inclusion ot a ses sion on TQM effectiveness at the CMA Chemical Industry Conference. Panels and Councils initiated more evaluation-focused efforts this year than ever before. Surveys and protocols for assessments of safety, regulatory performance and product per formance were launched to fulfill a vari ety of industry needs. In the survev area, EPA accepted the results of the Biocides Panel's antimicrobial exposure assess ment. Phenol Panel members conducted self-audits for safety performance and, on the basis of results, gave awards to members with the year's best safety records. Members of the Chemical Dis tributors Council began assessing vapor emissions from their facilities as a proac tive effort aimed at reducing emissions. Litigation is viewed as a last re sort, but Panels have been effec tive as petitioners in lawsuits. Filing of amicus briefs also allows panel views to be entered into the judicial record with a minimum of expense and effort. The Cumene Panel filed a judicial chal lenge against EPA seeking definition of "substantial" exposure limits by which the Agency requires extensive testing under TSCA. The Court ruled that EPA did not adequately justify the test rule for cumene. As a result of this ruling, EPA was forced to develop criteria for sub stantial exposure. Publication of final rules for testing hexamethylene diisocyanate and cyclohexane were de layed. The development of criteria for substantial exposure should result in a clearer understanding ot EPA's rationale tor required testing. Assessment protocols can help reduce the number of assessments performed and also can increase the level ot confi dence in the results. The Carrier Assess ment Council's Motor Carrier Evaluation Protocol, initiated this year, focuses on evaluating highway carriers. Protocols for evaluating other modes of carrier transport are also being discussed bv the Council. Through development of a self audit protocol, theChemical Distributors Council is seeking to improve and verify the safe handling and storage of chemi cals at distribution facilities. One more event this year deserves spe cial notice: The Fluorocarbon Panel, one of the largest and most influential panels in CHEMSTAR history, concluded its ef forts after sponsoring $24 million in re search. We congratulate the many per sons whose efforts made the Panel so successful over the past 18 years. In this time of economic uncertainty and belt-tightening, conservation of corpo rate resources is especially important. CHEMSTAR panels and councils con tinue to be excellent means for our mem bers to address specific needs, collectivelv, in a cost-effective manner. Robert A. Roland President Chemical Manufacturers Association June 1991 CMA 030654 BUSINESS COUNCILS Five CHEMSTAR Business Councils are now officially approved by CMA. These councils address research, datagathering, program and advocacy activities in those designated business sector or business function areas that are part of, or significant to, chemical manufacturing interests. During 1990-91, four new councils were organized -- Atmospheric Research, Carrier Assessment, Chemical Distributors, and Laboratory and Research Chemicals Councils. All four councils are now fully organized and proceeding towards their initial objectives. The fifth council -- the Total Quality Council -- successfully completed its first year of operation. At years end, this Council's membership included 29 CMA member companies. Atmospheric Research Chartered: 1991 Study Groups: Management Science Chairman: Ross Stevens E, I. du Pont de N'emours & Co. Council Manager: Elizabeth Gormlev The Council formed to address issues con cerning the impact of chemical industry emissions on regional and global atmo spheric change. A major focus will be on identifying and resolving scientific uncer tainties about effects of increased concen trations of chemicals in the atmosphere. The Council plans to obtain research data that will assist in developing chemical industry positions on such issues as Clean Air Act implementation and global cli mate change. The data also is expected to help provide a scientific foundation for the industry's position in the debates lead ing to a global convention for control of greenhouse gases. The Council established study groups to develop an operating structure, dues scheme, and a three-year research agenda. During the next year, the Coun cil vvill continue its membership drive for participation in the research program. A primary goal of the initial research effort will be to develop criteria for use in screening the materials emitted to the air -by the chemical industry." Carrier Assessment Chartered: 1991 Task Groups: Executive Publicity Standard Assess ment Protocol Third-Partv Assess ment System Chairman: Charles Verna E. 1. du Pont de Nemours & Co. Council Manager: Jonathon Busch The Council formed to address carrier safety issues, including the need for a cost effective means tor CMA members to meet the carrier safety provisions of the Re sponsible Care5 initiative. These provi sions require that CMA members estab lish a process for qualifying carriers that emphasizes safety fitness and regulatory compliance and that includes regular re views of carriers for safety and regulatory performance. The provisions also require CMA members to maintain a process for providing feedback and suggestions for improvement to carriers on their safety fitness and regulatory compliance. To accomplish these goals, the Council will; develop assessment protocols that can be used to evaluate carriers for safety and regulatory compliance; advocate and fa cilitate development of an impartial, thirdparty assessment system for evaluating carriers; and, pursue development of an accreditation process for third-party as sessors. The Council's initial efforts focused on developing an assessment protocol for evaluating motor carriers. The National Tank Truck Carriers and the American Trucking Associations participated with the Council in this effort. The Council also began developing a strategy for es tablishing a third-party assessment sys tem and a method for accrediting asses sors. The Council plans to develop a pilot program to test its standard assessment protocol for motor carriers and continue working towards a third-party assess ment system and an accreditation pro cess tor assessors. Council efforts will expand to include developing assess ment programs for marine, rail, and air carriers. The Council will develop and maintain liaison with appropriate CMA groups and external organizations as nec essary to accomplish its goals." Ch mical Distributors Chartered: Task Groups: a Legal Defense Chairman: Daniel VVenstrup CHEMCENTRAL Corporation The Council formed to address issues of concern to chemical distributor members ot'CMA. Council activities include: col lecting, evaluating and disseminating in formation on issues that affect chemical distribution: and advocating the interests of the chemical distributor sector. The Council began developing an imple mentation aid for the Responsible Care* Distribution Code. The Council also ini tiated a review of company safety train ing materials and began a proactive pro gram of data collection on vapor emis sions from facilities of its member compa nies. The Council plans to continue its current projects. In addition, the Council will develop an implementation aid for the Product Stewardship Code and address the impact of the HM 181 regulation on chemical distributors.' Council Manager: Langley Spurlock Laboratory and Research Chemicals Chartered: 1991 Task Groups; None Chairman: Javid Bashir Scientific Company The Council formed to address issues unique to the laboratory and research chemicals industry. Activities will in clude: commenting on regulatory and legislative proposals affecting the indus try; advocating the interests of the indus try before domestic and international or ganizations and government agencies; de veloping protocols and contracting for research; and, developing and sponsor ing educational programs to implement objectives of the Council. TheCouncil will focus first on identifying and analyzing new state legislation and regulations on labelling and transport of chemicals that affect member companies. The Council will advocate harmoniza tion between federal and state require ments.' Council Manager; Elizabeth Moran Total Quality Chartered: 1990 Task Groups: Domestic Affairs Education International Affairs Membership Publicity Supplier Assessment Chairman: Raymond Attebery Quantum Chemical Council Manager: Langley Spurlock The Council addressed the impact of Eu ropean requirements for certification of corporate quality systems under ISO9000 standards. To this end, the Council con tinued its efforts to facilitate develop ment of a U.S. program of ISO 9000 ac creditation and certification that is ac ceptable outside the U.S. In addition, the Council prepared an informational bro chure on ISO 9000, "Questions of Qual ity," for distribution within the industry, and initiated the development of ISO9000 implementation guidelines for the U.S. chemical industry. The Council formed to address quality management issues of concern to the chemical industry. Activities include: integrating quality concepts within the chemical and related industries; advocat ing the interests of the chemical industry before domestic and international qual ity standard-setting organizations and related government agencies; and encour aging the development of educational and training programs on quality man agement. The Council will continue to establish itselfas an active player in the U.S. volun tary standards system, intensify efforts to inform the chemical industry about the value of using total quality management principles to improve global competitive ness, promote the use of TQM tools to achieve industry initiatives such as Re sponsible Care, and develop a frame work for more efficient partnerships with suppliers. T cm 03065 NEW PANELS During 1990-91, ten new panels were requested and approved. Manufacturers and users ofsix individual chemicals -- Acetone, Carbon Disulfide, Hydrazine, Methyl Bromide, Sodium Bromide, and Vinyl Chloride -- and two chemical categories -- Nitrosamines and Toluenediamines -- organized. The two other groups were a consolidation -- Oxo Process -- and a significant expansion offocus -- Petroleum Additives -- ofexisting panels. Reasons for organizing range from a need to respond to pending or existing regulations to simply a proactive interest in promoting safety, customer education, emergency response, and better product evaluations. All ten panels are now fully organized and proceeding toward their initial objectives. Acetone Chartered: 1991 Task Group: Toxicology Research Chairman: Phillip Casterton Shell Oil Company Panel Manager: Barbara Francis The Acetone Task Group formed under the Ketones Panel in 1990 to address regu latory concerns of manufacturers, pro cessors, and users. In April, Task Group members decided to become a Panel. The Panel submitted comments to EPA on the proposed TSCA Section 4 end point rule for neurotoxicity and noted that the Agency had overlooked relevant, existing data that provide sufficient in formation to exclude acetone from the test rule. The Panel is co-funding a twoyear research program involving envi ronmental chamber studies of the effects of volatile organic emissions on photo chemical ozone formation. Co-sponsors include the Coordinating ResearchCouncil, the California Air Resources Board, the South Coast Air Quality Management District, and the National Aerosol Asso ciation. In addition, to assist solvent ce ment manufacturers with the accredita tion of products that may occur in po table water, the Panel submitted infor mation to the National Sanitation Foun dation. Efforts to have acetone approved by NSF are continuing. The Panel monitored European regula tory issues such as the occupational ex posure standings of the European Com munity, and the German MAK Commission's reconsideration of the TWA and STEL for acetone. CEFIC and the Panel are exploring technical liaison and information sharing activities. The Panel plans to address the recent designation of acetone by the Interagency Testing Committee to EPA for testing under TSCA Section 4.^ Carbon Disulfide Chartered: 1991 Task Groups: Risk Assessment Toxicology Research TSCA Testing Chairman: John Stewart Courtaulds Fibers, Inc. Panel Manager: Susan Flowe The Inter-Industry Committee on Car bon Disulfide, a group that formed in 1976 under the auspices of the Man-Made Fiber Producers Association, became a CHEMSTAR Panel in January. The Panel addresses pertinent safety, health, and environmental issues. In January, the Panel submitted comments on the draft toxicological profile for car bon disulfide developed by the Agency for Toxic Substances and Disease Regis try under SARA Section 110. In March, EPA proposed a TSCA Section 4 test rule for the testing of developmental and re productive toxicity for carbon disulfide. The Panel submitted comments and testi mony to the Agency. The Panel will continue to work with EPA on the proposed TSCA test rule. Additionally, the Panel plans to coordi nate with ACGIH, which recently identi fied carbon disulfide as a chemical under study for 1991-1992. The Risk Assess ment Task Group will address hazard assessment issues.^ Hydrazine Chartered: 1991 Task Group: Toxicology Research Chairman: Dave Hackathorn Mobav Corporation Panel Manager: Bonnie Bailey The Panel formed to support hydrazinerelated product stewardship activities. The Panel will work with regulatory agen cies and other concerned organizations in matters relating to satetv and health issues concerning hydrazine The Panel submitted an evaluation of the toxicologic database tor hydrazine to the American Conference of Governmental Industrial Hygienists. These data sup port the present TLV for hydrazine, and indicate that hydrazine is a weak animal, rather than human, carcinogen. Panel representatives presented these data to the ACGIH at its March meeting. The Panel also is establishing an open dialog with the Air Force, Navy, and NASA to explore a research program designed to provide the basis for an appropriate TLV for hvdrazine. The Panel is evaluating the classification of hydrazine under the new Clean Air Act and is developing comments regard ing the Credit for Early Reduction Pro posed Rule. These comments highlight the short half-life of hydrazine and its unique and restricted use, as well as lim ited exposure. The Panel additionally is sponsoring a one-hour LC50 study to clarify the Hazardous MaterialTransportationclassitication ot hydrazine hydrate. The Panel will continue to review and evaluate published and unpublished lit erature on the health effects of hydrazine in order to maintain a current, accurate point of reference for discussion ot the safe use of hydrazine products. When appropriate, the Panel will design, spon sor, and monitor additional testing.' Methyl Bromide Chartered: 1990 Task Group: None Chairman: Frank Handy Chemical Corporation Panel Manager: Bonnie Bailey The consortium of producers was formed as a n ad hoc group in 1982 to respond to an EPA Data Call-In. The group became a CHEMSTAR Panel in October. The Panel currently is working with EPA to satisfy the requirements of several FIFRA data call-ins and the 1986 Methyl Bromide Reregistration Standard. Stud ies that will fulfill the requirements are expected to be completed within the next four years. In March, the Panel initiated the global coalition of methyl bromide producers including the Association of Methyl Bro mide Industry Japan, the European Methyl Bromide Association, and the Panel. The coalition will respond to inter national issues about methyl bromide as they are raised by regulatory agencies. The global coalition currently is address ing concerns about the presence of methyl bromide in the atmosphere, and its po tential impact on stratospheric ozone * Nitrosamines Chartered: 1990 Task Group: Risk Assessment Analytical Assessment Formulation Chairman: Mark Thomson Uniroval Chemical Company Panel Manager: Susan Howe The Panel formed in June to identify and address impending federal and interna tional regulatory actions that potentially impact nitrosamines Products of inter est to member companies include: rub ber additives, secondary amines, cosmet ics components, 5oaps, detergents, and surfactants. The Panel initiated dialogue with OSHA to express concern with the recently pub lished, "Health Hazard Intormation Bul letin: N-Nitroso Compounds in Indus try." The Panel also interacted with FDA and the EPA Office ot Drinking Water to discuss a variety of issues of concern to participating companies. The Risk Assessment Task Group will author a revision of the chapter on Nmtrosamines in "Patty's Industrial Hy giene and Toxicology." Additionally, the Panel will continue evaluating risk as sessments for specific nitrosamine-containing compounds. In conjunction with these activities, the Analytical Assessment Task Group will evaluate methods to detect nitrosamines in various environ mental media.! CMA 030658 Oxo Process j Chartered: 1990 Task Groups: 2-EH Toxi cology Research EHA Toxi cology Research Butyraldehvde Toxi cology Research Butvraldehyde Environ mental Research Chairman: Richard Wise Union Carbide Corporation Panel Manager: Bonnie Bailey The Panel formed from a merger of the Ethvlhexanoic Acid Panel, and the 2Ethvlhexanol Panel along with its Butvr aldehyde Task Group. This enables mem bers to address issues on a broad range of chemicals that are starting materials, in termediates, or end products ot the same industrial process. The Panel developed comments on the proposed TSCA Section 4 end-point test rules for developmental and reproduc tive toxicity and for neurotoxicity. The comments address seven oxo process chemicals The Panel stated that not all of the chemi cals should be sublet to testing require ments. The Panel also questioned the scope and nature ot the testing required under the proposed neurotoxicity test rule. The Ethvlhexanoic Acid Toxicology Re search Task Group established an open dialogue with EPA and the General Ac counting Office to discuss the interpreta tion of a completed study conducted un der a TSCA Section 4 test rule. The Task Group plans to publish results of this test program. The Task Group also focused on demonstrating that there is no signifi cant human exposure to EHA. The2-Ethvlhexanol Toxicology Research Task Group continued to monitor progress in the oncogenicity studies bemgconducted in Germany m response to a TSCA Section 4 test rule. The in-life portion of the mouse and rat studies were completed. The final reports are due to EPA in February 1992, The Task Group also voluntarily initiated oral and dermal pharmacokinetic studies and a dermal toxicity study. These data will support toxicity studies and help to determine the potential health risks associated with hu man exposure." Petroleum Additives Chartered: 1990 Task Groups: Fuels Deter gent Performance Health, Environmen tal and Regulatory Product Approval Protocol Chairman: John Sanders Oronlte-Chevron Chemical Company Panel Manager: Carol Stack The Panel formed to interact with regula tory agencies and other organizations. Manufacturers of lubricant and fuel ad ditives expanded the scope of activities of the former Lubricant Additives Panel to include development of a Product Ap proval Code of Practice for engine testing of candidate oils and response to EPA Clean Air Act regulatory initiatives. The new activities extended beyond the char ter of the existing panel. A new Panel and three task groups therefore were estab lished. The Fuels Detergent Performance Task Group will develop consensus in the in dustry on EPA's rulemaking under Sec tion 211(1) of the Clean Air Act. Beginningjanuary 1995, the legislation requires that all gasoline sold in the U.S. contain detergents to prevent deposits in engines and fuel supply systems EPA will estab lish specifications for these additives by November 1992. Formerly the Lubricant Additives Panel, the Health, Environmental and Regula tory Task Group pursues research and regulatory activities, A joint CMA/Ad ditives Technical Committeeenvironmen tal toxicity research program on several classes of lubricant additives is in progress. The data will be used to sup port European environmental labeling requirements and anticipated U.S. envi ronmental hazard communication regu lations. The Task Group also has commit ted to participation in the OECD HPV voluntary testing program. The Task Group filed comments and tes tified on an EPA ANPR which proposed testing of fuel additive emissions to as sess health and welfare effects. EPA drafted the regulations under authority of the Clean Air Act. The Task Group is concerned about EPA initiatives to ex pand fuel registration and testing to in clude lubricant additives. The Product Approval Protocol Task Group promotes development of consis tent and reproducible engine testing pro cedures, cost-effective product approval testing, and product approval protocols. The Task Group interacts with other trade associations and societies that are inter ested in the product approval process. The Task Group drafted a voluntary in dustry Product Approval Code of Prac tice for candidate engine oils testing. The Code seeks to ensure that engine lubri cants meet intended performance levels, to improve cost-effectiveness by foster ing improved test precision, to improve communications bv defining standard processes understood by all stakehold ers, and to provide tor continuous im provement The Task Group is examin ing elements of the Code m preparation for implementation in March 1992. To facilitate the process, two Work Groups were formed to develop recommenda tions on handling of engine test precision and severity under the Code and to ad dress the handling of minor formulation changes. The Task Group seeks to estab lish a Monitoring Agency to act as an impartial organization providing indus try oversight, as well as administrative and advisory services related to applica tion of the Code." Sodium Bromide Chartered: 1990 Task Groups: None Chairman: Louise Wen Ethyl Corporation Panel Manager: Jonathon Busch The Panel was chartered in August to address health, safety, environmental, and regulatory issues. The Panel has focused primarily on research. The Panel initiated a study that evaluated the rela tive toxicides of bromine chloride and chlorine to aquatic organisms. This vol untary study involved both freshwater and saltwater species. The final study report will be completed and submitted to EPA in the summer of 1991. Results of the aquatic toxicity research will be used by EPA in developing water quality-based limitations to control discharges to water from facilities using activated sodium bro mide or bromine chloride as treatment chemicals. Future activities of the Panel will include monitoring and sponsoring research, and developing advocacy positions. The Panel will interact closely with interested orga nizations, such as the Utility Water Act Group and the EPA Office of Water." Toluenediamines Chartered: 1991 Task Group: Toxicology Research Chairman: James LaPrad BASF Corporation Panel Manager: Cecilia Spearing A Toluenediamines Panel was formed in 1980 to address an EPA ANPR on phenvlenediamines, including toluenediamines. EPA recommended carcinogenicity testing for TDA, but later decided that testing was not required. Ultimately, EPA referred the matter to OSHA for possible regulation. OSHA did not initiate rulemaking and the Panel terminated in 1987. In March, EPA pub lished the proposed end-point rule under TSCA Section 4 requiring testing for de velopmental and reproductive toxicity. 2,4-Toluenediamine was included in the proposed rule. The Panel was reacti vated by affected manufacturers to ad dress this rule. The Panel developed comments which were transmitted to EPA. The Panel also participated in the EPA public meeting on the proposed rule. As development of the test rule proceeds, the Panel will work with EPA and conduct testing as re quired.^ Vinyl Chloride Chartered: 1991 Task Groups: Education and Training Contractor Identification Railcar Equip ment Identification Communications Chairman: John Coburn Occidental Chemical Corporation Panel Manager: Has Shah A Vinyl Chloride Panel was formed un der CMA in 1974 to develop and assess health and safety data on vinyl chloride monomer. After funding several animal studies, the Panel shifted its focus to epidemiologic studies of workers. The Panel completed its research goals and terminated activity in 1990. In April, the Panel was reactivated by manufacturers to promote greater safety in the transportation of vinyl chloride. The Panel plans to form a mutual aid network to provide technical expertise and assistance at the scene of vinyl chlo ride transportation incidents when the shipper cannot respond promptly. The Panel also will share preventive preparation, response information and establish a communication network. The Panel will validate and enhance emer gency response preparation plans and increase the capability in critical areas of the distribution network to deal with transportation accident/ incidents involv ing vinyl chloride. In addition, the Panel will develop recommendations regard ing improvements in shipping equipment and procedures to enhance overall in dustry safety performance." CMA 030660 CONTINUING PANELS Fifty-three CHEMSTAR Panels are now officially approved by CMA. CHEMSTAR membership rosters during the year included 250 companies and 21 associations. Among the company members, 98 were members of CMA and 22 were non-US and non-Canadian. Participating companies and associations were represented on panels and task groups by approximately 340 persons with professional skills ranging from physical and biological sciences, through engineering and industrial hygiene to legal and business areas. Alkanolamines Chartered: 1982 Task Group: Toxicology Research Chairman: Edward Bentley Texaco Chemical Company Panel Manager: Jonathon Busch The Panel provided EPA with unpub lished health and safety studies and in formation on production, use, and expo sure under TSCA Section 8(d). The Panel also monitored several studies sponsored by the National Toxicology Program. These included range-finding oral devel opmental studies on monoethanolamine (MEA), diethanolamine (DEA), and triethanolamine (TEA), and a chronic dermal study on TEA. Following subchronic oral and dermal testing of DEA, NTP selected DEA for chronic der mal testing in rats and mice. The Panel prepared a status report summarizing the results of the testing of DEA by NTP. ~ ;e Panel completed voluntary dermal developmental studies with rats on MEA and DEA. The Panel submitted data and gave a presentation to the AmericanConference of Governmental Industrial Hy gienists regarding the lack of carcinoge nicity of TEA. The Panel formed to determine the toxi cological properties and environmental effects of alkanolamines in response to concern raised by a limited Japanese study implicating TEA as a possible carcinogen in mice. However, results of subsequent published and unpublished studies in rats and mice have indicated that TEA is not carcinogenic. The Panel will voluntarily initiate dermal developmental studies with rabbits on MEA and DEA. Plans also are underway to voluntarily sponsor in vitro and in vivo dermal absorption studies on these two alkanolamines. Other plans include pub lishing research results, developing writ ten comments regarding ACGIH's new carcinogen classification scheme, submit ting a proposal to ACGIH to adjust the TLV forTEA, and submitting a petition to EPA to adjust the statutory default RQ for DEA because of it's listing in Section 112 of the new Clean Air Act.^ Alkylphenols and Ethoxylates ________ Chartered: 1987 Task Groups: Dodecylphenol Environmental Survey Modeling Study Toxicology Chairman: Richard Bennett Texaco Chemical Company Panel Manager: Robert Romano The Panel formed the Dodecylphenol Task Group to address the TSCA Section 4 end-point rule on developmental and reproductive toxicity. Manufacturers of dodecylphenol on the Panel were joined by one non-Panel member company on the Task Group. The Panel formed to determine the health and environmental effects ofalkylphenols and ethoxylates in manufacture and use. Initial efforts focused on responding to EPA concerns on the chemical fate and environmental effects of nonylphenol. The Panel maintains liaison with the Soap and Detergent Association on scientific and regulatory issues. Membership is open to manufacturers, users, and formulators. In February, the Panel participated in an international workshop on alkylphenols and ethoxylates hosted by the Swedish EPA. The workshop addressed environ mental issues and possible alternatives to alkylphenols and ethoxylates. The Panel will continue to work with the Swedish EPA and agencies of other coun tries. The Panel also will continue to educate the U.S. regulatory community on the results of Panel research.^ * CMA 030661 Benzene ______________ Chartered: 1976 Task Group: Toxicology Research Chairman: Roger Daniel The Dow Chemical Company Panel Manager Carol Stack Panel activity focused on responding to an ACGIH TLV Committee proposal to lower the benzene threshold limit value from lOppm to 0.1 ppm TWA. The Panel submitted written comments to ACGIH opposing the proposal and provided oral testimony at an ACGIH hearing in March. The Panel found evidence to support the proposal lacking, and stated that the cur rent OSHA PEL of 1.0 ppm TWA more than adequately protected benzene-exposed workers against unreasonable health risks. The Panel also continued support of a research program on benzene-induced leukemogenesis in cooperation with API. The two-phase program investigates the effect of benzene and its metabolites on hematopoiesis in the mouse and man. Since its formation, the Panel has pur sued an active research and advocacy program. Responding to a NTOSH occu pational study linking benzene exposure to leukemia, the Panel sponsored an in dustry epidemiology study in 1983. Also, in cooperation with API, the Panel estab lished a research program investigating subchronic toxicity, metabolism and re productive effects. The Panel's immediate focus will be on basic research; however, regulatory ac tivities are expected to continue in re sponse to EPA regulation of toxic air pol lutants under the 1990 Clean Air Act Amendments." Brominated Flame R tardants Chartered: 1990 Task Groups: Analytical Chemistry Executive Committee Toxicology Research Users' Group Chairman: David McAllister Great Lakes Chemical Corporation Panel Manager: Has Shah The Panel continued developing analytical protocols to determine levels of polvbrominated dibenzodioxins and furans in commercial samples of eight brominated ethers. These protocols are being developed under the TSCA Section 4 test rule for dibenzodioxins and dibenzofurans. EPA approval of these protocols is expected by September 1991. In October, the Panel submitted com ments on the German Hazardous Sub stance Ordinance through the European Brominated Flame Retardant Industry Panel. The Panel recommended that if the Ordinance is revised to regulate the concentrations of brominated diben zodioxins and furans in manufacture, use and disposal of products, it should be limited to 2,3,7,8-substituted brominated compounds. Also, the regulatory values in the revised ordinance should reflect the toxicity difference between chlori nated and brominated dibenzodioxins and dibenzofurans, and the toxicity dif ferences between dioxins and furans. The Panel awaits issuance of the final ordi nance. In December, the Panel provided com ments to EPA on the Executive Summary for OECD Cooperative Risk Reduction Activities for brominated flame retar dants. The Panel commented that the uses of polvbrominated biphenyl oxides and ethers, or products containing them, do not present unreasonable nsks to hu man health or the environment. The Panel will provide additional comments when the full document is published. The Panel initiated a research protect in March to confirm the blood levels of polybrominated dibenzodioxins and furans in five BASF workers. The results of the actual blood analysis are expected in Sep tember 1991. The consortium originally formed in 1985 under the auspices of the Fire Retardant Chemicals Association, and became a CHEMSTAR Panel in 1990. The Panel formed to address the inclusion of bromi nated flame retardants in EPA's proposed' regulation on dioxins and dibenzofurans, the publication of pyrolysis studies dem onstrating that brominated diben zodioxins and dibenzofurans can form from brominated diphenyl ethers, and the Interagency TestingCommittee's rec ommendations for health and environ mental effects testing of certain bromi nated flame retardants. The Panel will continue to work with EPA during reviews of analytical proto cols submitted under the TSCA test rule, and will respond to the proposed TSCA Section 4 test rule when it is published. The Panel also will work with EPA in responding to the OECD request to de velop a Screening Information Data Set for decabromo-bisphenol-A and octabromodiphenyl oxide. The Panel will CMA 03066 continue to monitor European regula tory activities and to coordinate L ,S and European industry on BFRs through its liaison with EBFRIP. The Panel has sched uled a workshop in September 1991, to update users of bronunated flame retar dants on regulatory, health, environmen tal, and safety issues.* Biocides Chartered: 1986 Task Groups: Antimicrobial Expo sure Assessment Arsenic Acid Executive Legislative Mercury Compounds Regulatory Scientific Chairman: Claude Wolf .Valeo Chemical Company Panel Manager: Has Shah Much of the Panel's effort was directed toward EPA's implementation of the FIFRA reregistration program. As a re sult, the Agency made important modifi cations in pesticide labeling, adverse ef fect reporting and registration List A ge neric data call-ins. The Panel submitted comments on the Phase 3 Reregistration Guidance to EPA and OMB in 1989, Ultimately, OMB au thorized EPA to require more extensive adverse effects data m Phase 3 Reregis tration than in an earlier policy. The Panel expressed concerns about the man ner in which the OMB authorization was granted and plans to pursue this issue to forestall EPA actions against registrants which have complied with the earlier policy In 1989, the Panel submitted comments to OMB opposing EPA's request tor generic approval of data call-ins for List A chemi cals. Panel representatives participated in meetings with OMB and EPA staff concerning the generic approval. OMB reversed its earlier position, limited EPA's authority, and required EPA to submit each data call-in for specific approval. OMB also reserved authority to require EPA, on a case-by-case basis, to substan tiate its data call-in requests and to seek public comment concerning its requests. The Panel successfully promoted a sys tem that will ensure the reregistration of salts m two List B chemical cases that EPA had planned to cancel The salt forms are found onlv in formulations and it is the Panel's position that data supporting the reregistration ot the tree acid forms of the chemicals should -upport all salts. The Panel obtained reduced paperwork re quirements tor -alts registrants and ex pects EPA to accept its arguments for reliance on analog data. The agreements reached for these two List B chemicals will serve as models tor similar chemical cases on List C and possibly on List D. Increasing concern about the impact of pesticides on food safetv makes it criti cally important that Congress recognize industrial biocides as a distinct segment of the pesticide industry. The Panel moni tored legislative activities in areas of food safety, pesticide exports, FIFRA Amend ments, and registration maintenance fees. Legislative representatives from Panel member companies spent much time vis iting Congressional offices, and educat ing members of Congress and their staffs about industrial biocides. A White Pa per highlighting the unique characteristics of industrial biocides was widely distrib uted. In April, Panel Chairman Claude Wolf testified before the House Subcommittee on Department Operations, Research and Foreign Agriculture on FIFRA and pesti cide regulations. The testimony empha sized the need for distinguishing between agricultural pesticides and industrial bio cides because of differences in their char acteristics, use-patterns, and exposure potentials. The Panel continued to monitor the imple mentation of SB 950 and Proposition 65 in California and provided information and compliance strategy advice to its mem bers. In addition, through its California counsel, the Panel obtained information on litigation and administrative develop ments under existing regulatory pro grams, and advance notice of adverse political developments. In 1990, the Canadian government re leased a report designed to revamp pesti cide registration. The Panel submitted comments on the report and gave input at a meeting in Ottawa in November. The Panel plans to continue its involvement as Canada implements the recommenda tions in the final report. The Antimicrobial Exposure Assessment Task Group submitted its exposure as sessment study to EPA. The study was accepted by the Agency, The Task Group is developing a means to allow the cita tion and use of this data by its members and a system to protect the compensability of the data. mmm > < / CMA 030663 The Mercury Compounds Task Group completed aquatic toxicity, avian toxicltv, skin sensitization, and subchronic dermal toxicity testing with phenvlmercunc acetate in response to EPA reregistration requirements. The Inorganic Arsenicals Task Force con tinued to generate data in response to EPA's reregistration standard and a pre viously issued data call-in. Results from 14 studies were submitted to EPA, and additional studies were initiated at sev eral testing laboratories. In addition, the Task Force continued to negotiate with EPA over other data requirements for reregistration. The Panel formed in 1986 to respond to the California Department of Food and Agriculture Data Call-In Notices on bio cidal chemicals registered in the state. The DC Is required that registrants sub mit data on chronic toxicity, oncogenicity, reproductive effects, teratogenicity, mu tagenicity, and neurotoxicity. The Panel since has focused on a variety of issues impacting the biocides industry as a whole, and various task groups have ad dressed issues surrounding specific bio cides. The Panel will continue to focus on EPA's implementation of the FIFRA Amend ments. EPA is expected to publish a number of wide-ranging proposals to amend the pesticide regulatory scheme during 1991 and anticipates issuing its "safer pesticide" policy The Panel will monitor and respond to these develop ments. This policy may have a significant impact on many products registered by Panel members. The impact will in large part depend upon whether EPA decides to cancel the registration of products upon a finding that a "safer" pesticide has been registered for the same use. Because FIFRA is scheduled tor reauthorization, the Panel will monitor legislative activities closely. The Panel will pay special attention to legislation affecting the export of pesticides and maintenance fees, A number of states are reexamining their regulations of pesticides and have amended, or are planning to amend, their laws and/or regulations. The Panel will continue to monitor these activities and take action to protect the interests of Panel members. The Panel also will continue to monitor the Canadian registration over haul and will work with agencies to pro vide scientific input for the development of a better system.1 Butadiene Chartered: 1984 Task Groups: Toxicology Research Environmental Industrial Hygiene Ethylene/ Propylene OSHA Activities Chairman: Norman Morrow Exxon Chemical Americas Panel Manager: Elizabeth Moran In August, OSHA published a proposed rule to regulate butadiene exposures in the workplace. The Panel developed ex tensive written testimony on the work place standard and then, along with its expert witnesses, presented oral testi mony in hearings during January and February. In developing its comments and testimony, the Panel and the major user association, the International Insti tute of Synthetic Rubber Producers, worked cooperatively. The Panel pro vided the expertise on toxicology and risk assessment issues and IISRP pro vided expertise on epidemiology issues. The American Petroleum Institute joined the Panel's efforts by participating in the OSHA rulemaking and by joining the Panel. The Panel commented on the ATSDR draft toxicogical profile on butadiene. The Panel also commented on a California Air Resources Board proposal to list buta diene as a Toxic Air Contaminant. In all rulemakings, the Panel presented evi dence that the regulatory agencies had overestimated the potential risk to hu mans by basing their risk assessments on a mouse bioassay conducted by the Na tional Toxicology Program rather than on rat bioassays and epidemiology stud ies in workers which do not show a con sistent response. To provide further in formation on the potential risk to humans of butadiene exposure, the Panel began a four-year, $1.5 million research program aimed at understanding the species dif ferences in response to butadiene expo sure and at developing data that will support alternative risk assessment meth odologies. The Panel continued its fugitive emis sions study, to collect data that can be used by companies in estimating plant emissions more accurately. The Panel also successfully negotiated a consent order CHA 030664 under TSCA Section 4, for testing of 4vinvl cvclohexene. The consent order focuses on comparing the biological ac tivity of 4VCH to butadiene, thereby sav ing several million dollars in testing costs. The Panel is voluntarily conducting a workplace monitoring study on 4-VCH The Panel formed in the aftermath of EPA consideration of butadiene under TSCA Section 4(f). The Panel aimed to collect and evaluate information needed to as sess safety, environmental, and health issues arising from production, storage, transportation, use, and disposal of buta diene. The Panel provided comments to the Agency on two risk assessments and worked with the Agency in assessing "short-term" releases of butadiene. EPA then referred butadiene to OSHA under TSCA Section 9(a), for development of a workplace standard. The Panel will continue to follow the development of the OSHA workplace standard on butadiene and is currently preparing post-hearing comments. The Panel also is following development of Clean Air Act Amendments and will com ment appropriately. The Panel will con tinue its research activities and begin con sent order testing of 4VCH. In addition, the Panel will interact with IARC, EPA and ACGIH in their evaluations of the cancer classification of butadiene.' Butylated Hydroxytoluene Chartered: 1977 Task Groups: None Chairman: Vacant Panel Manager: Bonnie Bailey The Panel continued cooperative efforts with the FDA and the European BHT Manufacturers Association (EBMA) through meetings and information ex change. The Panel was organized to conduct the research and advocacy necessary to sup port the continued use of BHT in food additive applications. In 1978, the Panel filed comments in response to an FDA proposal for interim regulations requir ing testing to resolve safety questions. To date, FDA has not issued an interim regu lation. The Panel submitted a Citizen Petition in 1986 requesting that FDA is sue a regulation recognizing a prior sanc tion for use of BHT. The FDA has not yet announced a date for its decision on the Petition. The Panel is developing a submission to the EPA, requesting that the EPA issue a regulationacknowledging the prior sanc tion status of BHT. The Panel is addition ally preparing an accompanying infor mation package containing a review of studies previously submitted and new information regarding the EBMA's Chronic Toxicity Study of BHT, The Role of Hepatocellular Injury In the Chronic Tox icity of BHT, presently scheduled for completion in early 1992. The Panel will additionally request a review by FASED of the data, supporting the conclusion that BHT is safe under its intended condi tions of use in food, before formulating a regulatory position. The Panel will continue to cooperate with the FDA in its continuing evaluation of BHT and will maintain working relations with the EBMA through information ex change.^ Chlorinated Pool Chemicals Chartered: 1989 Task Groups: Transportation Hazard Assess ment Research Chairman: Bruce Jacobsen Olin Corporation Panel Manager: Kathleen Roberts The Panel produced a bulletin and video tape on proper procedures for storing and handling chlorinated pool chemi cals. These were distributed in the U.S., Europe, and Japan to educate and train firefighters and other emergency response personnel. The Transportation Task Group drafted a bulletin which contains guidelines for transporting calcium hy pochlorite and chlorinated isocyanurates. The bulletin is intended for shippers of pool chemicals and personnel respon sible for in-transit storage. The finished bulletin will include information on per tinent federal transportation regulations. The Panel formed to promote safety prac tices worldwide in the processing, pack aging, warehousing, transportation, and use of chlorinated pool chemicals. Panel members include producers of calcium hypochlonte and chlorinated isocyanu rates worldwide. In response to a proposed reclassification of oxidizers by the National Fire Preven tion Association, the Panel is investigat ing testing to assess bum rates of large and small scale fires to provide informa tion on warehousing and packaging of pool chemicals. In addition, the Panel CMA 030665 will sponsor research to measure chloro form releases from swimming pools. The study will measure ambient airborne chloroform concentrations associated with public swimming pools under vari ous conditions in order to evaluate the indirect production of the chemical The Panel also will continue to test chlori nated pool chemicals in other research programs to respond to regulatory re quirements.^ Chlorine Dioxide Chartered: 1988 Task Groups: Communication FIFRA Office of Drinking Water Chairman: Doug Simpson Olin Corporation Panel Manager: Robert Romano The Panel began a 90-day subchronic study on sodium chlorite in response to FIFRA data call-in requirements. The Panel also is performing environmental tests on chlorine dioxide under the FIFRA reregistration program. The Panel con tinues to work closely with the EPA Of fice of Drinking Water on the upcoming standard for sodium chlorite. The Panel published proceedings of the symposium on chlorine dioxide cosponsored with EPA and the American Water Works Association Research Foundation in 1989. The Panel formed in anticipation of an EPA proposal to regulate chlorine diox ide under the Safe Drinking Water Act by 1993. In addition, the State of California contracted for a risk assessment on chlo rine dioxide and sodium chlorite. The Panel aims to gather, review, generate, and disseminate information on chlorine dioxide and its precursors, sodium chlo rite and sodium chlorate. The Panel mom- tors and interacts with regulatory agenciesand fosters scientific communications Primary focuses of the Panel are genera tion, applications, health effects, safety, and test methods of chlorine dioxide Future Panel activities include comple tion and final audit of the sodium chlorite subchronic study. Panel representatives will continue to interact with EPA on FIFRA data call-ins and reregistration, and with the Office of Drinking Water. The Panel will undertake additional test ing which EPA may require under FIFRA, The Panel will spend a significant amount of time reviewing and commenting on EPA's Chlorine Dioxide Health Ad visorv Report which is the basis for the Drinking Water Standard. As a follow up to its first successful forum, the Panel is planning a multi-cosponsored international sympo sium on chlorine dioxide in the spring of 1992.1 Chlorobenzenes Chartered: 1974 Task Groups: Toxicology Research FIFRA Data Call-In 1,2,4-Tnchlorobenzene Chairman: James Bryant Standard Chlorine Chemical Co., Inc. Panel Manager Carol Stack The Panel continues to sponsor research to meet 1,2,4 -trichlorobenzene (TCB) test ing requirements under TSCA Section 4 and a FIFRA Data Call-In on para-dichlorobenzene (PDCB). A comparative phar macokinetics study on PDCB was com pleted and submitted to EPA. The study will be a determining factor in the Agency's decision on the need to conduct multiple species chronic inhalation stud ies. The manufacturers of TCB have ini tiated dietary oncogenicity studies in rats and mice. The Panel formed to sponsor voluntary research on chlorobenzenes. The focus on research remains, but now the empha sis is on completing mandated research on health and environmental effects. The Panel continues to provide technical sup port for the advocacy activities ot the Chlorobenzenes Producers Association, an affiliate of the Synthetic Organic Chemical Manufacturers Association. The Panel's TSCA testing program will continue through June 1995, with sub mission of the final oncogenicity studies reports to EPA. The other primary activ ity will be compliance with the FIFRA Data Call-In on PDCB. On a voluntary basis, the producers of PDCB also are developing a physiologically-based phar macokinetics model for use in risk assess ment.! CMA 030666 Cobalt Chartered: im Task Group. Toxicology Research Chairman: David Bebout The Hall Chemical Company Panel Manager Susan Howe The Panel submitted comments to the Agency for Toxic Substances and Disease Registry (ATSDR) on the draft toxicologi cal profile tor cobalt. The Panel sug gested that ATSDR prepare a separate protile for radioisotopes, rather than in clude them in the toxicological profile for cobalt. Additionally, the Panel expressed concern with ATSDR's position that equates the toxicity of all cobalt com pounds, pointing out that while cobalt is considered an essential nutrient for hu mans, some cobalt compounds can be considered toxic, and some cobalt com pounds can be considered non-toxic. The Panel formed to interact with regula tory agencies and other appropriate or ganizations on cobalt safety, health, and environmental issues. The Panel first focused on the tune 1990 1ARC re\ lew ot cobalt and cobalt compounds. Thev in teracted with the Cobalt Development Institute in successfully providing valu able information for use m the 1ARC re view. In the future, the Panel will address in dustrial and environmental issues that affect cobalt. Issues identified forinteraction include: requesting separate RQs for specific cobalt compounds of concern that were included on theCERCIA list, due to the listing of cobalt compounds under the new Clean Air Act; interaction with ACGIH which has listed cobalt oompoundsas chemicals understudy in 19911992; and possible interaction with the OECD voluntary testing program tor high volume production chemicals.' Cresols Chartered: 1984 Task Group: Advocacy Chairman: Kirby Boston Vterichem Company Panel Manager: Barbara Francis The Panel submitted final reports for the testing conducted on three cresols iso mers under a TSCA Section 4 test rule. After submission of the reports required under the test rule, the Panel formed the Advocacy Task Group to address other regulatory issues. In October, the Task Group submitted comments to ATSDR on the draft toxicological profile for o-, mand p-cresols. In the comments, the Task Group noted that the Agency had failed to consider the data submitted under the TSCA Section 4 test rule. The Panel formed in 1984 in response to the TSCA Section 4 test rule. The Panel has worked with the EPA Chemical Test ing Branch, Office of Solid Waste, and the National Toxicology Program to ensure that logical and scientifically sound test ing programs are conducted on cresols. The Panel will evaluate EPA's Risk Man agement assessment of the TSCA Section 4 program when it becomes available. The Advocacy Task Group will continue to monitor cresols regulatory issues and alert the Panel to needs for further activities.' CMA 030667 Crystalline Silica IWHiH Chartered; 1989 Task Groups; Administrative Analytical Methods Health Effects Regulatory and Legal Chairman: Joseph Shapiro Unimin Corporation Panel Manager: Elizabeth Gormley Membership in the Panel remained steadv at around 50 members. The Panel contin ued to await the National Toxicology Program's decision on listing crystalline silica in its Sixth Annual Report on Car cinogens as "reasonably anticipated to be a carcinogen." The Administrative Task Group focused on developing a strategic plan and worked closely with the Health Effects Task Group to outline comple mentary scientific research objectives. Meanwhile, the Regulatory and Legal Task Group organized comments for sub mission to OSHA and MSHA on the Haz ard Communication Standard. The Panel also filed comments on permissible expo sure limits for crystalline silica in MSHA's Air Contaminant Rule. The Analytical Methods Task Group selected authors for state-of-the-a rt reviews which will be used as the basis for discussions at a Panel workshop in fall 1991. The Panel formed to address the 1987 International Agency for Research on Cancer listing of crystalline silica as a "probable" carcinogen. Classification as a probable carcinogen automatically re quires firms to comply with OSHA Haz ard Communication Standard cancer la belling requirements. The Panel began with nine members, dedicated to bring ing together the silica industry to speak with a united voice on scientific, regula tory and analytical concerns stemming from the IARC action. The Panel will continue to express its concerns to agencies on the use of auto matic triggers for labeling decisions. Panel members will follow up on a request to visit with OSHA officials, and will moni tor developments at MSHA and CPSC. The Panel will continue efforts to expand the membership and financial resources to fund a focused research program. The AMTG will continue to plan for a work shop and a related international confer ence on methods for detecting and ana lyzing crystalline silica content, now scheduled for August 1992. The Panel will continue to monitor and respond to other technical, regulatory, and legal is sues as they arise. ^ Cumene Chartered: 1985 Task Groups: Health Effects Environmental Effects Chairman: Gene Hamilton Georgia Gulf Corporation Panel Manager Barbara Francis In compliance with a TSCA Section 4 test rule, the Panel sponsored health and en vironmental effects and environmental fate testing. The required testing was completed in 1990. The Panel decided to conduct further research to clarify results of the 14-week subchronic study. The Health Effects Task Group is reviewing the draft report of the follow up study, which will be submitted to the EPA in 1991. Through a judicial challenge, the Panel sought definition of "substantial" expo sure limits bv which the Agency can re quire testing under TSCA Section 4(a)(1)(B). In 1990, the Court ruled that EPA did not justitv the test rule for cumene because meaningful criteria for defining "substantial or significant" environmen tal release and human exposure had not been established. The Court remanded the test rule to EPA and directed the Agency to provide a rationale for its ex posure findings. The Panel formed as a result of the Interagency Testing Committee's desig nation of cumene for priority testing un der TSCA Section 4. The Panel's objective is to collect information that will allow assessment of health and environmental effects arising from production, storage, use and disposal of cumene. The Panel is currently considering whether to petitionfor removal of cumene from the Clean Air Act Hazardous Air Pollutants List. In addition, the Panel will continue to interact with EPA and other agencies on hazard and risk assess ment issues. 1 CMA 030A&8 Cyclohexane Chartered: 1985 Task Group: Toxicology Research Chairman: Russell Cook Phillips Chemical Company Panel Manager: Jonathon Busch EPA action on a final TSCA Section 4 test rule is expected by December 1991. In preparation for the final test rule, the Panel has reviewed bids from various laboratories to perform health effects re search The Panel also informed EPA that it is interested in meeting the data needs by testing under a consent order agree ment The Panel submitted comments to EPA opposing a SARA Section 313 listing pe tition filed by the National Resources Defense Council and the Governors of New Jersey, \'ew York, and Vermont. The Panel's comments outlined reasons why cyclohexane does not meet any of the statutory requirements for listing under Section 313. The comments also provided arguments why chemicals hav ing only indirect health effects should not be included on the Section 313 list. In addition, the Panel initiated advocacy efforts to eliminate unnecessary report ing under the new Clean Air Act. Cyclohexane manufacturers formed the Panel to address the Interagency Testing Committee's intent to designate cyclo hexane for priority testing under TSCA Section 4. A proposed test rule on cyclo hexane was published by EPA in 1987. The Panel plans to comment on how EP A's new TSCA Section 4 exposure finding policy impacts the proposed test rule for cyclohexane. The Panel also plans to comment to EPA on the anticipated TSCA final test rule and will sponsor required research as appropriate." Dibenzofurans/ Dibenzodioxins Chartered: 1984 Task Groups: None Chairman: Robert Kaley Monsanto Company Panel Manager: Elizabeth Gormley The Panel successfully argued its case as an intervenor in the Environmental De fense Fund and National Wildlife Fed eration appeal of a 1988 summary judg ment of their lawsuit against EPA. In the original suit EDF and NWF sought to force the Agency to initiate a TSCA Sec tion b rulemaking on dioxins. The federal court ruled in favor of the Agency's right to "set its own priorities" m the face of citizens' petitions. The decision of the lower court was upheld. The Panel formed when EDF and NWF filed the TSCA Section 21 Petition. In addressing the EPA response, the Panel commented to the Agency on proposed rules under TSCA Sections 4 and 8. Final rulemakings on the two sections require analyses of chemicals for the presence of dibenzofurans and dibenzodioxins as impurities and the reporting of produc tion, processing, use, exposure, and dis posal data. The Panel will continue to monitor the dioxin issue and respond when appro priate to the emergence of Toxicity Equivalency Factors being applied in regulatory frameworks, particularly at the state level." CMA 0306A9 Diisocyanates JMHBM Chartered: 1988 Task Groups: Isocyanates TSCA Tes ting Maximum Achiev able Control Technology Toxicology Research Transportation Chairman: James Chapman Mobav Corporation Panel Manager: Cecilia Spearing The Panel continues to work with EP A to ensure that the Agency has all of the data necessary to make informed decisions during implementation of Title [II of the Clean Air Act. A Maximum Achievable Control Technology Task Group was es tablished to explore the effect of these standards on the member companies' operating procedures with specific refer ence to toluene diisocvanate. During the year, the L'S Department of Transporta tion deleted MDI from the Poison Inhala tion Hazard Table in its revision of the 1990 Emergency Response Guidebook. Representatives ot the Panel and the TSCA Testing Task Group met with the Execu tive Director of the Interagency Testing Committee, select members of the Com mittee and EPA to address 25 of the 43 isocyanates in the intent to designate cat egory of its 26th Report to the EPA Ad ministrator. The Panel formed to develop and dis seminate information on the safe han dling of diisocyanates, including: tolu ene diisocvanate, methvlene-bisdiphenyl diisocvanate, hexamethvlene diisocy anate and, methvlenebis-dicvclohewl diisocvanate. Monitoring impending regulations affecting the production or use of dusocvanates and developing re sponses as needed are also key Panel activities. The Panel will continue to work with the State of California on implementation of Proposition 65. Work will continue be tween the Panel and several states as state Air Toxic Regulations are being devel oped. Emergency Response Prepared ness Guidelines for methylenediphenvl diisocyanate and toluene diisocvanate will be prepared under the auspices of the Panel. The Panel is establishing a Transportation Task Group to examine ihe impact of HM-181 on packaging stan dards for the shipment of MDI. Conver sations between the Panel and the EPA Test Rules Development Branch to de velop appropriate responses under TSCA Section 4 will continue. The Panel also will continue to interact and coordinate activities with SPI, the Polyurethane Foam Association, and the International Insti tute on Isocyanates.^ Dinitrotoluenes Chartered: 1989 Task Group: Toxicology Chairman: Thomas Mamot Air Products and Chemicals, Inc. Panel Manager Barbara Francis As part of a voluntary agreement with EPA and agencies of Germany, the Panel is conducting a pharmacokinetics study. The results of this study will be submitted to the agencies in late 1991. In addition, the U S. member companies have pro vided environmental release information on 2,6- and 2,4-dinitrotoIuene to the EPA. The Panel formed to permit U.S. manu facturers to work with Bayer AG on a voluntary testing program. Representa tives of the U.S. EPA and German agen cies identified DNTs as possible subjects for testing by companies in both coun tries. The agencies' stated objectives were to promote sharing of the cost of research and to ensure the availability of adequate hazard data. The Panel member compa nies and Bayer AG agreed to undertake a pilot pharmacokinetics project in response to the agencies' request. The Panel will submit the pharmacoki netics study to theGerman and U.S. agen cies and will continue to interact with them to assess results.T CMA 030670 Ethyfen Dibromide Chartered: 1982 Task Groups: None Chairman: Vernon White Chemical Corporation Panel Manager: Robert Romano OSHA has not yet issued a final rule revising the federal Occupational Stan dard for ethylene dibromide. The Panel therefore had no need to meet this year. The Panel formed to address the OSHA Standard with the goal of ensuring that reasonable regulations are adopted. Once the rule is issued, the Panel will review the requirements and evaluate the effects on the industry.T Ethylene Dichloride Chartered: 1974 Task Groups: None Chairman: Vacant The Panel did not participate in any new activities this year. The Panel originally formed to address Federal and State agencies in all safety and health issues arising out of the pro duction, distribution, and use of EDC. Initially, the Panel focused on evaluating scientific literature, identifying data gaps, and undertaking additional toxicological studies to improve the research data base. The Panel voluntanly sponsored studies of chronic inhalation, metabolism, and teratogenicity. The Panel will continue to monitor agency activities and take action as appropri ate.^ Panel Manager: Kathleen Roberts Ethylene Glycol Chartered: 1986 Task Group: Toxicology Research Chairman: William Snellings Union Carbide Corporation Panel Manager Kathleen Roberts The Panel completed its voluntary re search program. The Panel formed to augment the toxicological data base. In particular, the Panel focused on the po tential for developmental toxicity and pharmacokinetics research in mice and rats. The Panel will continue its activity by addressing federal regulatory issues, such as the Clean Air Act, CERCLA, and RCRA. In addition, the Panel intends to monitor and respond to pending state legislation. The Panel is interested in investigating ethylene glycol denaturants and their ef fectiveness in reducing accidental poi sonings. With the data generated from the voluntary research program, the Panel may conduct a risk assessment which would be used to respond to regulatory concerns, 1 CMA 030671 Ethylene Oxide Chartered: 1981 Task Groups: Scientific Industrial Hygiene Environmental Epidemiology Toxicology Safety Chairman: Ronald Van Mynen Union Carbide Corporation Panel Manager: Robert Romano The EthvleneOxide Industry Council and Chemical Industry Institute of Toxicol ogy cofunded an EO pharmacokinetics physiological modeling study being con ducted atCHT. The EOIC also tracked the reauthorization of the Clean Air Act, which could affect EO production facili ties Theresultsof theEOlC field bagging study for fugitive emissions were accepted by EPA and will be used by the Agency in its Fugitive Emissions Regulation. In addition, EOIC worked with ATSDR to determine the fate of the SARA Section 110 EO toxicological profile report. The EOIC began an EO epidemiology analy sis because the epidemiology studies do not agree with the results of the animal studies. In March, the Panel also spon sored another successful "EO Informa tion Exchange" workshop on transporta tion and safety issues related to EO pro duction. The Industrial Hygiene Task Group continued to evaluate additional protective clothing materials for EO pen etration and breakthrough. The Panel formed to evaluate the results of an animal study that may affect OSHA and EPA regulatory proceedings on EO. The EOIC addresses many regulatory and scientific activities in an effort to provide both agencies with enough information to make reasonable and scientificallv sound decisions on regulatory controls. The CUT pharmacokinetics physiologi cal modeling study will continue, as will a broad review of all EO epidemiology data. The EOIC industry-wide fugitive emissions bagging study results will be made available to all members to aid in further quantifying EO emissions for SARA Section 313 reporting and risk as sessment. More "Information Exchange" workshops focusing on safety and han dling of EO are planned by the Panel.' Fluoroalkenes Chartered: 1987 Task Groups: Specific Chemi cals Producers Specific Chemi cals Toxicology Chairman: Sharron Laas E. I. du Pont de Nemours & Co. Panel Manager Kathleen Roberts In compliance with a TSCA Section 4 rule, the Panel conducted mutagenicity, subchronic toxicity, and oncogenicity test ing on four fluoroalkene monomers -- vinyl fluoride, vinylidene fluoride, hexafluoro-propene, and teratrafluoroethene. Most of the testing pro gram was completed and the results sub mitted to EPA for review. The excep tions, the vinyl fluoride and vinylidene fluoride oncogenicity studies, willbe sub mitted to EPA in early 1992. At an EPA TSCA Section 4 Public Pro gram Review, the Panel provided com ments on lower tier testing under the test rule. Based on those comments, EPA decided to rescind the requirements for the hexafluoro-propene and vinyl fluo ride heritable translocation assays. In addition, after reviewing the results from a mouse micronucleus test, the Agency rescinded the requirement for an oncogenicity study with hexafluoropropene. The manufacturers of the fluoroalkene monomers originally formed an ad hoc coalition to address the ITC's 1980 desig nation of fluoroalkenes for priority test ing consideration under TSCA Section 4. The coalition reorganized as a panel un der the auspices of CMA after the test rule was final. The Panel is awaiting EPA's review of the vinyl fluoride alkaline elution and unscheduled DNA synthesis tests to de termine if the mouse specific locus test will be required. The Panel plans to con tinue its interaction with EPA in the evalu ation of the fluoroalkenes testing require ments. ^ CMA 030672 Glycol Ethers Chartered: 1980 Task Group: Toxicology Research Chairman: Richard Wise L ruon Carbide Chemicals and Plastics Company Inc. Panel Manager: Carol Stack Panel research and advocacy activities continue to focus on ethvlene-based gly col ethers. A voluntary research program on ethylene glycol butyl ether (EGBE) is m progress. The program includes m vitro hemolysis studies in rat and human red blood cells, and the development of a phvsiologically-based pharmacokinetics model tor EGBE risk assessment The Panel is conductinga developmental neu rotoxicity study on triethvlene glycol methyl ether required under a TSCA Sec tion 4 test rule. The Panel commented on the EPA TSCA Section 4 endpoint test rule for neurotox icity and presented oral testimony at the EPA hearings. Ethylene glycol monoethvl ether (EGEE) is among the ten chemicals proposed fortesting. The comments seri ously questioned the inclusion of EGEE in the proposal since all the EPA-based criteria for listing were not met. A final ruling is anticipated in the spring of 1992. The Panel plans to file a petition to delist certain glycol ethers from the category of glycol ethers listed as toxic air pollutants in the Clean Air Act amendments. A pre petition conference was held with EPA/ OAQPS staff to discuss the category prob lem and the application of EPA delisting criteria to the glycol ethers. A petition to delist diethvlene glycol butyl ether and its acetate, and the triethylene glycol ethers is under preparation. Petitions to delist other members of the category may be developed and filed at a later date. The Panel monitored state activities and responded to regulatory and legislative initiatives in Illinois and South Carolina, respectively. In Illinois, the Panel was successful in removing EGBE from a list of toxic air pollutants. The effort in South Carolina to remove the glycol ethers cat egory, and list only those of toxicological concern, was not successful. In Texas, the Panel worked through the Texas Chemi cal Council to request formulation of a definition tor glycol ethers on the Texas Air Control Board's Standard Exemption List. Panel manufacturers of EGME and EGEE and their acetates are tracking regulatory developments within OSHA. A notice of Proposed Rule to establish new work place standards will be published shortly. The Panel formed to develop an adequate toxicity data base on ethvlene-based gly col ethers, provide information to users and government agencies on the safety of the chemicals, and promote scientifically sound regulatory action. The Panel will complete testing under TSCA, and voluntary testing is expected to continue with possible involvement in the OECD HPV testing program. In the advocacy arena, the Panel will pursue delisting efforts as they relate to the CAA, and will monitor state activities. The Panel also will petition EPA to raise the reportable quantityofcertain glycol ethers under CERCLA to greater than one pound. 1 CMA 030673 Hexamethylene Diisocyanate Chartered: 1988 Task Group: Toxicology Research Chairman: Donald Lamb Mobay Corporation Panel Manager: Kathleen Roberts The Panel prepared for the TSCA Section l Test Rule by identifying candidate test ing laboratories and requesting propos als and bids. The Panel formed to address the inclu sion of HD1 on the ITC priority list of chemicals tor testing under TSCA Section 4. In its proposed response, EPA identi fied oncogenicity, mutagenicity, repro ductive toxicity, developmental toxicity, neurotoxicity, comparative pharmacoki netics and hydrolysis testing. The pro posed testing program was based on a "substantialorsignificant" exposure find ing under TSCA Section 4(a)(1)(B). Due to a Court directive requiring EPA to develop criteria to support this finding, the Agency had to delay the publication of the final test rule. When EPA com pletes the development of the required exposure standards, it will judge the test ing needs. The Panel will proceed with the TSCA Section 4 testing program as soon as EPA issues the final rule." Hydrogen Fluoride Chartered: 1988 Task Groups: Advocacy /Communications CAER / Risk Communi cation Management Materials of Construction Medical & Toxicology Mutual Aid Personal Protective Equipment Storage Systems Transportation Chairman: James Muir Allied-Signal Inc. Panel Manager Elizabeth Gormley After much preparation by an ad hoc study group of management contacts from producers as well as users groups, the Panel held an exploratory meeting in January. The purpose of this meeting was to explore inclusion of users and suppliers of raw materials as members, and expansion of the Panel focus to in clude advocacy activities. Since then, the Panel has more than doubled its mem bership, offering a tiered dues structure and levels of membership. The Panel has added a Management Group to provide oversight and guidance as well as an Advocacy/Communications Task Group. The expanded Panel submitted comments to California's South Coast Air Quality Management District (SCAQMD) ex pressing concern over a proposed ban on the use of HF. The Panel also monitored the passage of the Clean Air Act provi sion relating to HF and planned how to respond to EPA's need for information to complete the mandated study, due in late 1992. The Task Groups accelerated their activities and timetables for participation in advocacy initiatives. The Panel formed to provide a forum for U S. and Mexican producers and ship pers to share information on safety in the manufacture, handling and transporta tion of, and emergency response proce dures for, hydrogen fluoride. The Panel will continue to follow and participate in EPA's program to prepare a study of the industry. The Panel also will consider whether to participate m a lawsuit filed against the SCAQMD The Task Groups will continue to focus on completion of the initial set of recom mended guidelines. ^ CMA 030674 Hydroquinone Chartered: 1984 Task Group: Toxicology Research Chairman: Robert Brothers Eastman Kodak Company Panel Manager: Jonathon Busch The Panel completed a required testing program for hydroquinone under TSCA Section 4. All required data and reports were submitted to EPA and the Panel prepared a Research Summary Report outlining the findings and conclusions of the studies The Panel awaits a response from the Agency. If EPA accepts the Panel-sponsored research, then the Panel will have achieved its research objectives. The Toxicology Research Task Group published abstracts of Panel-sponsored research, and gave poster-presentations on the research at the Society of Toxicol ogy and Teratology Society meetings. The Panel also cooperated with the Nonprescnption Drug Manufacturers As sociation and the Cosmetic, Toiletry, and Fragrance Association by providing them with summaries and final reports of the Panel-sponsored studies. The Panel formed in response to a pro posed TSCA Section 4 test rule published by EPA in 1984. Subsequently, the Panel submitted extensive comments to the Agency and presented data at a rulemak ing heanng. The Panel voluntarily spon sored a study to assess potential develop mental effects from exposure to hydro quinone. The Panel also participated in peer reviews of NTP carcinogenicity bioassavs of hydroquinone with rats and mice. The Panel plans to publish the findings of its research program in appropriate sci entific journals. The International Agency for Research on Cancer (IARC) identified hydroquinone as a priority chemical for reviewin 1991. The Panel will ensure that its published research findings are avail able to IARC for use in its evaluation " Isopropanol Chartered: 1987 Task Group: Toxicology Research Chairman: James Quance Exxon Chemical Company Panel Manager: Cecilia Spearing In compliance with a TSCA Section 4 test rule issued in 1989, the Panel is testing isopropanol for health effects. Testing requirements include: subchronic toxic ity, reproductive toxicity, developmental toxicity and neurotoxicity, mutagenicity, pharmacokinetics, and oncogenicity. The last, a two-year oncogenicity study, was started in February. The Panel formed to address health ef fects concerns about isopropanol raised by the ITC in its 19th Report to the EPA Administrator. The Panel's objective is to collect information that will aid in the assessment of health effects arising from production, storage, transportation and use of isopropanol. The Panel will continue to monitor stud ies required under the test rule as well as interact with EPA regarding interpreta tion and evaluation of the test results," CMA 030A7S Ketones Chartered: 1980 Task Group: Toxicology Research, Chairman: James Quance Exxon Chemical Company Panel Manager: Barbara Francis The Panel submitted comments to EPA on the inclusion of methyl isobutvl ke tone in the T5CA Section 4 proposed end point rule for developmental / reproduc tive toxicity and neurotoxicity testing. Panel comments cited numerous over looked studies as a reason for excluding MIBK from the final rule. The National Sanitation Foundation, at the request of solvent cement manufac turers, is evaluating methyl ethyl ketone for accreditation for use in substances that may occur in potable water. To assist the solvent cement manufacturers, the Panel provided data to NSF and became actively involved in the accreditation re view. The Panel submitted comments in re sponse to ATSDR's identification of pri ority data needs for isophorone and three other chemicals underSARA Section 110. Based on the negligible potential for hu man exposure to isophorone at NPL sites, and because many of the research needs have been filled through voluntary stud ies, the Panel is advocating that isophor one be given a low priority for further regulatory action ATSDR concurred and the recently announced list of 38 priority chemicals does not include isophorone. The Panel formed to address EPA activi ties on methyl isobutvl ketone, methyl ethyl ketone, isophorone, and mesityl oxide. Subsequently, the Panel included acetone in its focus. The Panel negotiated testing programs with the EPA to supple ment the data base on MEK, MIBK and isophorone In addition, the Panel was actively involved in discussions with the Agency on testing needs for MO and filed a petition for review of the final TSCA Section 4 test rule. The Court asked the Agency to reconsider the test rule in light of significant changes in MO use. The Panel is currently negotiating with EPA to resolve the mesitvl oxide testing issue through a consent agreement. The Panel is considering volunteering MEK, MIBK, and MO for the OECD HPV ExistmgChemicalsScreening Program. Addi tionally, the Panel will explore liaison with the CEFIC Oxygenated Solvents Committee." r Metal Catalysts Chartered: 1984 Task Groups: Environmen tal Regulations Industrial Hygiene Chairman: William Deering Gulf Chemical and Metallurgical Company Panel Manager Susan Howe The Panel submitted comments in July to the California Department of Health Ser vices to support a recommendation to add nickel and nickel compounds to the list of chemicals which present no signifi cant risk of cancer by the route of inges tion. The Panel submitted comments m October to the EPA Office of Drinking Water on the proposed rule to establish MCLGs and MCLs for nickel and nickel compounds. In February, the Panel sub mitted comments to ACGIH on the pro posal to lower the TLVs for all nickel compounds to 0.05 mg/m3. Due to coop eration with the Nickel Producers Envi ronmental Research Association, Insti tute of Scrap Recycling Industries, Inc., and the National Association of Metal Finishers, the industry comments were successful in persuading ACGIH to keep nickel in the "intend to change" category until September 1992. The Panel formed to collect and evaluate information necessary to assess safety, environmental, and health issues con cerning metal- containing catalysts used in industrial processes. The Panel origi nally focused on a research program to characterize the toxicity profiles of metal catalysts, with particular emphasis on nickel-containing materials. Over the last several years, Panel focus has changed with an increase in advocacy activities m the areas of industrial and environmental regulatory concerns. The Panel is continuing liaison with NiPERA, ISRI, NAMF, and the European Catalysts Manufacturers Association. The Industrial Hygiene Task Group will de velop information on the economic im pact on industry should ACGIH lower the TLVs for all nickel compounds. The Task Group also will respond to the pro posed OSHA PEL update scheduled for Winter 1991. The Environmental Regula tions Task Group plans to address im port/export of waste regulations devel oped under the RCRA, as well as the publication by ATSDR in Fall 1991, of priority data needs for nickel and chro mium compounds.^ CMA 030676 *4 Methylenedianiline Chartered: 1982 Task Groups: Risk Assessment Medi cal & Toxicology Analytical and Indus trial Hygiene Chairman: Roger Daniel Dow Chemical USA Panel Manager: Elizabeth Moran The Panel continued to encourage OSHA to expedite the proposed workplace stan dard for VIDA. The Panel formed in response to the 1TC recommendation that 4,4'-methylenedianiline be considered for priority test ing under TSCA Section 4. In 1983, EPA decided that no additional testing was necessary, but designated MDA as the first "significant risk" chemical under TSCA Section 4(0 Ultimately, in 1985, the Agency referred the chemical to OSHA under the authority of TSCA Section 9, The Panel participated in the first nego tiation of a workplace standard for MDA under the Occupational Safety and Health Act. The Panel is awaiting publication of the final rule for a workplace standard which is expected in 1991.1 Naphthenates Chartered: 1983 Task Groups: None Chairman: Michael Scott Moonev Chemicals, Inc. Panel Manager: Has Shah No new activities were undertaken by the Panel this year. The Panel formed as a result of an 1TC recommendation to EPA that calcium, cobalt, and lead naphthenates be consid ered for priority testing under TSCA Sec tion 4. Subsequently, the Panel expanded its scope to address EPA concerns in the pesticides area. The Panel will decide on a course of ac tion when it receives the EPA evaluation of its dermal absorption study. The studv was part of a voluntary testing program developed by the Panel and the Agency in lieu of a TSCA Section 4 test rule.* Oleylamine Chartered: 1984 Task Groups: None Chairman: Edwin Bisinger Akzo Chemicals Inc. In 1989, the Panel completed the first tier of the TSCA Section 4 Test Rule. Due to the results, EPA has stated that the Panel will not have to conduct the additional studies under the second and third tier requirements of the test rule. The Panel formed in response to the pro posed test rule under TSCA Section 4 requinng pharmacokinetics, genetic ef fects, subchronic toxicity (including neu rotoxicity and reproductive tract effects), and teratogenicity data. The Panel is awaiting the outcome of the Agency's further evaluation of the test data. With the original research objec tives fulfilled, the Panel will decide on future activities in Fall 1991.* Panel Manager Susan Howe Phenol E Chartered: 1988 Task Groups: Regulatory Toxicology Research Video Chairman: Edwin Fraini Dow Chemical USA Panel Manager: Susan Howe Panel members shared information on OSHA's Lockout/Tagout Rule, safety programs used in plant shutdown situa tions, safety motivation, reduction of human errors in the workplace, and operatorcertification and training. The Panel completed the first self-assessment by member companies of worker safety in phenol-producing plants, using the ProActive Safety Index. The first annual awards ceremony was held in September at which Texaco Chemical Company was recognized as the Industry Leader in Safety Performance, and Georgia Gulf Corporation was recognized for the Most Improvement in Safety Performance. The Regulatory Task Group submitted com ments on the ITC designation of phenol for TSCA Section 4 testing. The ITC rec ommended testing for: oral and inhala tion pharmacokinetics; inhalation subchronic; reproductive effects; and neu rotoxicity. The Toxicology Research Task Group initiated a voluntary pharmacoki netic research program evaluating the comparative profiles of phenol disposi tion by oral bolus, drinking water and inhalation routes. The Task Group is working closely with EPA to coordinate this research with the proposed testing under TSCA Section 4. The Panel formed to promote greater safety in the production, transportation and use of phenol. Member companies exchange nonproprietary safety informa tion on topics that relate to transportation and handling issues that involve phenol. Health and environmental issues con cerning phenol are addressed by the Regu latory Task Group. The current research program is monitored by the Toxicology Research Task Group. The Panel is exploring production of a video on the safety, handling and trans portation issues concerning phenol that will target worker and customer safety Additionally, the Panel is investigating the presentation of a seminar on safety in loading and handling. The Regulatory Task Group will continue to monitor and address the TSCA Section 4 test rule, the Clean Air Act, RCRA reauthorization and the development of OCPFS regulations * Phosgene Chartered: 1972 Task Groups: Engineering and Safe ty Practices Environmental Industrial Hygiene Medical and Toxicology Chairman: W. E. Irby Mobay Corporation Panel Manager Robert Romano The Panel continued its sponsorship of research at New York Medical College on treatment methods for accidental expo sure to phosgene. The research now fo cuses on canine in-life studies and has identified several medications that are effective in treatment of phosgene expo sure. The Panel also is sponsoring studies in phosgene air dispersion modeling and mitigation. The Panel continues its phos gene industrial hygiene surveys. The Panel formed to improve industry ability to safely manufacture, handle, and use phosgene. Predicting and control ling ambient concentrations of phosgene from accidental releases has become an important Panel objective. The proceedings of the Panel-sponsored international symposium, "Remote Moni toring: Current Technology and Future Developments Applicable to Air Toxics, Including Phosgene,'' will be published in 1991. The Panel will continue its regu lar program of information exchanges among member companies on safety tech niques. In addition, the Panel will con tinue monitoring increasing regulatory interest in phosgene. The Panel plans to conduct a workshop on countermeasures to phosgeneexposure in September 1991 ' CMA 030678 Phthalate Esters Chartered: 1973 Task Groups: Toxicology Research Environmental Research Food and Drug Appli cations Phthalic Anhydride California Issues FDA Toxicology Research Chairman: Jeffrey Felder Monsanto Company Panel Manager: Marian Stanley Due to comments submitted by the Panel, the Chesapeake Bay Advisory Commit tee removed di-2-ethylhexyl phthalate (DEHP) from the list of Toxics of Concern under the Chesapeake Bay Toxics Reduc tion Program. The Panel commented on the proposed Ambient Water Quality Criteria for Pro tection of Aquatic Life and the Proposed National Primary and Secondary Drink ing Water Regulations. Comments also were submitted on the inclusion of phtha late esters in the Corrective Action for Solid Waste Management Units at Haz ardous Waste Management Facilities pro posed rule. In continuation of the Panel's coopera tive program of information exchange with the CEFIC Plasticizers Sector Group, Panel members attended the third joint meeting of the two groups held in Berlin, Germany in May. The two groups will continue meeting annually, and plan to pursue some joint projects during the next year. The Panel formed in 1972 to address envi ronmental issues. In 1976, the Interagency Testing Committee listed the alkyl phtha late category for test rule development under TSCA Section 4. The ITC also included health effects testing in its con cerns following the release by NTP of bioassay results on DEHP and di-2ethylhexvl adipate. In 1980-81, the Panel worked with EPA to develop the first Negotiated Testing Agreement in lieu of a TSCA Section 4 test rule. The testing was completed in 1984 and the results were submitted to the Agency along with a proposal for further environmental test ing. In 1988, the Panel and EPA agreed on an environmental testing program, which is being conducted under a consent or der. Reproductive and developmental toxic ity of phthalate esters appears to be the least well understood of all the research questions facing the Panel. To further understanding, the Panel has contracted with an expert to review and analyze the published and unpublished literature. The outcome of the review will be a pub lished article in a peer reviewed journal The work in particular will be used to support the Panel's advocacy in Califor nia. Later in 1991, the Panel will complete the first phase of environmental testing be ing conducted under a consent order. The Panel will work with ATSDR and EPA to avoid inappropriate or unneces sary testing requirements on DEHP, DBP and other phthalates under SARA 110. The Panel also is planning to publish results of the environmental effects test ing to provide better data to states devel oping regulations, particularly in the water area. Additionally, the Panel will address the inclusion of phthalates in the air toxics title of CAA amendments, and develop a strategy for deleting phthalic anhydride from the ait toxics list." CMA 030679 Polychlorinated Biphenyls Chartered: 1981 Task Groups: None Chairman: John Craddock Monsanto Company Panel Manager: Elizabeth Gormley The Panel and the National Electrical Manufacturers Association submitted comments on PCB maximum contami* nant levels and goals under the Safe Drink ing Water Act. The two associations also followed up with a petition to EPA to reconsider the analytical method of choice. The Panel along with NEMA and the Edison Electric Institute's Utility Solid Waste Activities Group began prepara tions for response to an EPA announce ment of a proposed rulemaking on PCB disposal issues, particularly the cleanup of old spills. This industry coalition also testified at hearings of the California Sci ence Advisory Panel, advocating that PCBs not be considered reproductive toxi cants under the provisions of Proposition 65 and of the State of Massachusetts De partment of Environmental Protection on cleanup standards. The Panel formed to represent the inter ests of the industry during implementa tion of the TSCA Section 6 regulations for the control of PCBs, mitigation of trans former fires, and retention of electrical equipment containing PCBs. The Panel and the other members of the industry coalition await the publication of EPA's ANPR. The Panel also will follow the emerging concern of Toxicity Equivalency Factors being applied to PCBs in a regulatory framework, particu larly at the state level. ^ Rubber Additives Chartered: 1979 Task Groups: Toxicology Research MBT MBT Joint Test Spon sors/Importers of Rubber Articles Chairman: Michael Smith The Goodyear Tire and Rubber Company With the completion of the study, "TwoGeneration Reproduction Study in Rats with MBT," the MBT Task Group ful filled the requirements of the TSCA Sec tion 4 test rule for 2-mercaptobenzothiazole. Final reports from all of the testing required by EPA have been submitted and the Panel is awaiting the outcome of the Agency's evaluation. The Panel formed to support research that would expand the rubber additives safety and health issues data base. To date, the Panel has collected information on approximately 65 chemicals classified as rubber additives, and has sponsored more than 5800,000 in research. A layman's summary of each of the stud ies performed under the TSCA test rule will be completed in Fall 1991. The sum mary will be used to disseminate the test results to the joint test sponsors and im porters of rubber articles containing MBT, The Panel also will address environmen tal issues in the near future." Panel Manager Susan Howe Specialty Acrylates/ Methacrylates Chartered: 1987 Task Groups: Scientific Issues Membership Regulatory Issues Chairman: Georjean Adams Minnesota Mining and Manufacturing Company The Panel made progress in the first tier of toxicological tests that are part of a three-stage research program agreed upon with EPA. The Agency was in formed of the progress and made several valuable contributions to the testing pro tocols. The Panel commented to NTP on the proposed testing of several acrylates. The Panel formed to address EPA con cerns about new and existing specialty acrylates and methacrylates. The Panel's major emphasis is on working with the Agency to remove restrictions on the de velopment and marketing of new prod ucts. Current Panel membership consists of producers, importers, formulators, and users of these chemicals. The Panel will continue the research pro gram and work with EPA to ensure that the program is satisfactory to both indus try and the Agency. The Panel will also continue efforts with EPA to remove dis tribution restrictions on important new chemical products in this category. 1 Panel Manager Marian Stanley CMA 030680 Titanium Dioxide Chartered: 1977 Task Groups: None Chairman: Jerry Blacker SCM Corporation Panel Manager: Jonathon Busch The Panel submitted scientific data and gave a presentation to NIOSH regarding the lack of carcinogenicity of titanium dioxide. These efforts were in response to NIOSH classifying titanium dioxide as a potential occupational carcinogen. The Panel noted that its own position was consistent with determinations made by ACGIH, EPA, FDA, and IARC. The Panel was successful in having NIOSH re-ex amine its position. The Panel also began developing a new air emissions model for titanium tetrachloride. Current TiCl4 air emissions models are inadequate, and the Panel hopes that the new model will more adequately predict downwind dis persion and concentration following ac cidental releases. The new model will track dispersion of secondary reaction products in addition to TiClv The Panel continued information-shar ing sessions in which member company representatives discussed case histones of accidental releases and safety prob lems encountered with TiCl,. The Panel hopes to enhance worker and commu nity safety by sharing experiences and information on equipment improvements to control releases. In other efforts, the Panel also submitted a petition to EPA to adjust the RQ for TiCl,, submitted an epidemiology study on TiCl4 to NCI, and submitted scientific data to the publisher Van Nostrand Reinhold. These latter ef forts were successful in having the haz ard rating for titanium dioxide lowered in the publication, Dangerous Properties of Industrial Materials (Eighth Edition, Sax and Lewis, editors). The Panel formed in 1977 to address toxi cology and occupational issues associ ated with titanium dioxide and its manu facture. The Panel plans to continue development ofa TiCl4 air dispersion model, to provide scientific data to NIOSH and other inter ested organizations, and to develop ad vocacy positions on proposed regula tions. ^ Trimellitate Esters Chartered: 1983 Task Groups: Toxicology Research Terephthalic Acid Chairman: Dean Finney Eastman Chemical Company Panel Manager Elizabeth Moran The Terephthalic Acid (TPA) Task Group convinced EPA to delete TPA from the list of chemicals requiring annual emis sions reporting under the Emergency Planning and Community Right-to-Know Act (EPCRA). EPA had proposed to delist TPA, but wanted to make delisting con tingent on results of testing that would be required under TSCA Section 4. Task Group comments convinced EPA to delist immediately so that companies will not be required to report TPA emissions for 1990. The Task Group also commented on the proposed endpoint test rule for reproductive effects testing ofterephthalic acid. The ITC designated tris 2-ethylhexyl trimellitate (TOTM) for priority testing under TSCA Section 4 in 1982. The rec ommended testing included metabolism. subchronic, mutagenicity, and environ mental effects testing. The producers immediately formed a special task group under the Phthalate Esters Panel and sub sequently formed the Panel to pursue a negotiated testing agreement. The Panel reached an agreement with EPA in 1984 and has since completed all testing on TOTM and submitted the data to EPA. In 1990, the Panel added terephthalic acid to the scope of its activities when EPA pub lished a proposal to delist TPA from EPCRA. When EPA completes its review of the data on TOTM, the Panel will work with Agency scientists to interpret the test data and to determine the need for additional testing. The Task Group will continue to monitor the development of the proposed TSCA testing on TPA.* CMA 030681 Vinylidene Chloride Chartered: 1974 Task Groups: None Chairman: Zeb Bell PPG Industries, Inc. Panel Manager: Kathleen Roberts The Panel provided comments to the California Air Resources Board regard ing categorization of air pollutants and participated in a meeting with the Na tional Air Pollution Control Techniques Advisory Committee. As background for its efforts to have EPA withdraw its proposed TSCA Section 4 test rule, the Panel monitored ATSDR's prioritization of vinylidene chloride and designation of data needs. The Panel began an investi gation into a TEAM study and a corre sponding report associating vinylidene chloride with a list of cancer risks associ ated with indoor pollutants. The Panel formed to sponsor research on the potential toxicologic effects and phar macokinetics of VDC. The objective was to develop data for ensuring the safety of workers involved in the manufacture, handling, and use of the chemical, as well as the safety of communities surround ing production facilities. The Panel will continue to respond to AT5DR and EPA testing proposals and will monitor other regulations as they occur. ^ Water Additives Chartered: 1985 Task Groups: Specific Chemicals Chairman: Randy Deskin Cyanamid Company Panel Manager. Robert Romano The Panel has filled data gaps for ulti mate certification under the consensus Water Additives Standards. The Panel continues addressing data needs for the following chemicals: polydiallyldimethylammonium chloride (PDADMAC), copolymers of epichloro- hydrin and dimethylamine (EPI/DMA), and polyacrylamide (PAM). The Panel has task groups for each of these chemi cals which have performed an exposure assessment and sponsored tests. The toxi cological tests included Ames, rat micro nucleus, rat teratology, and 90-day subchronic. The Panel met with toxicol ogy staffs from each of three certification organizations. The Panel formed to address regulations of direct and indirect potable water addi tives. The objectives are to monitor regu latory policies, improve communication, review toxicology data, develop advo cacy positions, ensure that any water ad ditives program is designed and admin istered in a cost-effective manner, and ensure that water additives are used in a manner that does not compromise public health, safety, or the environment. The Panel has decided to work with the National Sanitation Foundation in devel oping a water additive certification pro gram for PDADMAC, EPI/DMA and PAM. The Panel also will participate m American Water Works Association ac tivities where water certification pro grams will be further discussed. Certifi cation packages for the three chemicals will be developed for use by each mem ber company, with ultimate certification by NSF for each of the three chemicals.^ CMA 030632 COMPLETED PANELS 2-Ethylhexanol Chartered' 1986 Task Groups: Toxicologv Research Butyraldehvde Butyraldehvde Environ mental Butyraldehvde Toxicology Chairman: Richard Wise Union Carbide Chemicals & Plastics Company Inc. Panel Manager: Has Shah The Panel decided to merge with the 2Ethylhexanoic Acid Panel in October of 1990 to form a Panel of chemicals in volved m the oxo process. The newlvformed Oxo Process Panel will address a broader range of chemicals. The 2-EH Panel formed to address the TSCA Section 4 test rule issued by EPA at the request of the National Toxicology Program NTP requested this testing when budget cuts forced the cancellation of its two-year rat and mouse bioassay. The final rule was published in August 1989 The Toxicology Research Task Group continued to monitor the oncogenicity studies in progress at BASF in Germany. The Panel initiated dermal and oral phar macokinetic studies that are scheduled for completion in late 1991. gather information on the production and use of butyraldehvde in the L'.S. The survey provided data on worker, general population, and environmental exposure levels. The survey was submitted to EPA in response to an ITC recommendation that health and ecological effects testing be conducted under TSCA Section 4 if significant worker and general popula tion exposure to the chemical was dem onstrated. The survey, which included all producers and several mapr users of butyraldehvde, showed very low work place, general population, and environ mental exposure levels. The Task Group concluded that health and environmen tal effects studies are not warranted. Data from an EPA independent assessment of the exposure levels was similar to that of the Panel. The Task Group awaits a deci sion from EPA on the test rule. The Butyraldehvde Environmental Re Further activities involving 2-EH will be search Task Group conducted a survey to conducted under the Oxo Process Panel. * Fluorocarbons Chartered: 1973 Task Groups: None Chairman: Robert Orfeo Allied-Signal Inc. Panel Manager: Elizabeth Gormley No new activities were undertaken by the Panel this year. A brochure outlining the history of the Panel, "Searching the Stratosphere," was published. The Panel completed all research work in progress and terminated in September. The Panel formed to fund research to determine the environmental fate of chlorofluorocarbons. Throughout its lifetime, the Panel supported projects totalling more than $26 million. Sponsored stud- ies addressed atmospheric chemistry, at mospheric measurements, modelling, and trend analysis. The Panel focus broad ened in recent years to include the moni toring of developments in the climate change and biological effects research areas. A report listing the investigators and sum marizing the results of all the projects funded by the Panel will be published in late 1991," Lubricant Additives Chartered: 1985 Task Group: Environmental Research Chairman: Charles Keller Exxon Chemical Company Panel Manager: Carol Stack When the Petroleum Additives Panel formed, the Lubricant Additives Panel was absorbed as a task group. As the Health, Environmental and Regulatory Task Group, the rormer Panel has fo cused on lubricant and fuel additives. The Panel organized to address antici pated international marine pollution con trol regulations. An immediate concern was the need to generate marine aquatic toxicity data to support proper pollution categories tor bulk shipments and to in vestigate the efficient stripping of un loaded tankers The Panel was largely successful in meet ing its original goals. It sponsored stud ies and submitted data on ATC classes of lubricant additives to the IMO Bulk Chemical Handling Committee which used the information in assigning the additives to pollution categories. As a Task Group of the Petroleum Addi tives Panel, future activities will depend on developments in the health, environ mental and regulatory areas. ^ CMA 030683 CHEMSTAR COUNCILS AND PANELS FINANCIAL STATUS For the Twelve Months Ended May 31, 1991 1 > 1 3 4 5 6 7 8 9 10 11 12 13 14 IS 16 17 18 19 20 21 22 23 24 25 26 27 28 23 30 31 32 33 34 35 36 37 33 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 COUNCILS & PANELS Atmospheric Research Carrier Assessment Chemical Distributors Total Quality Acetone Alkanolamines Alkylphenols and Ethoxylates Benzene Biocides Brominated Flame Retardant Butadiene Butylated Hydroxytoluene Carbon Disulfide Chlorinated Pool Chemicals Chlorine Dioxide Chlorobenzenes Cobalt Cresols Crystalline Silica Cumene Cyclohexane Dibenzofurans/Dibenzodioxins Diisocyanate Dinitrotoluenes Ethylene Dibromide Ethylene Dichloride Ethylene Glycol Ethylene Oxide Fluoroalkenes Fluorocarbons Glycol Ethers Hexamethylene Diisocyanate Hydrazine Hydrogen Fluoride Hydroquinone Isopropanol Ketones Metal Catalysts Methyl Bromide Methylenedianiline Nitrosamines Oleylamine Oxo Process Petroleum Additives Phenol Phosqene Phthalate Esters Polychlorinated Biphenyls Rubber Additives Sodium Bromide Specialty Acrylates/Methacrylates Titanium Dioxide Trimellitate Esters Vinyl Chloride Vinylidene Chloride Water Additives Balance June i, 1990 0 0 0 56,800 0 22,500 487,900 398,700 835,800 21,900 151,900 32,300 0 20,800 31,300 683,200 21,600 44,300 68,600 353,200 19,500 10,200 55,400 155,100 0 4,900 104,900 110,900 339,600 1,070.600 591,500 400 0 22,400 20,200 678,700 207,000 29,500 0 53,300 0 12,400 1,393,600 33,500 31,900 192,600 1,359,600 58,700 222,700 0 794,100 9,800 42,100 26,000 43,800 426,400 $ 11,295,300 '-- Contribution Receipts 30,000 85,000 55,000 65,000 74,200 269,900 35,000 0 815,000 777,500 1,595,300 28,000 81,000 72,700 239,000 280,200 60,000 42,500 108,000 56,100 30,000 5,000 180.000 0 0 0 0 422,300 96,500 0 342,900 9,000 15,000 147,900 0 1,439,400 385,300 96,200 209,200 0 50,000 0 325,600 292,200 119,500 66,000 656,000 62,000 1,700 51,100 310,000 44,300 0 0 0 180,000 $ 10,071,500 Interest Revenue 100 0 1,300 7,100 300 8,200 33,800 21,100 72,500 9,800 16,500 1,900 700 2,300 3,900 45,900 1,300 3,900 4,000 24,700 1,600 900 4,500 11,100 0 400 4,700 10,500 22,300 46,700 49,900 200 100 2,400 1,000 72,600 18,200 1,700 2,600 3,600 800 1,000 122,200 7,400 3,600 15,100 110,000 6,000 14,500 900 81,700 1,200 3,000 1,900 2,900 32,900 $ 910,900 .... ......... -- Expenditures 6,000 32,800 34,800 56,100 10,600 113,800 284,600 322,100 832,000 600,700 1,069,100 38,700 74,700 67,600 112,900 591,600 52,900 40,000 157,900 244,600 51.400 5,200 167,700 37,400 0 0 85,800 196,400 213,400 942,300 412,700 1,300 9,500 85,600 18,200 1,301.800 309,100 71,700 56,500 11,600 40,400 800 327,700 89,700 112,500 112,400 715,100 67,700 90,000 30,600 158.300 43,300 14,100 4,300 27,500 259,100 $ 10,684,900 Balance May 31,1991 24,100 52,200 21,500 72,800 63,900 186,800 272,100 97,700 891,300 208,500 694,600 23,500 7,000 28,200 161,300 417,700 30,000 50,700 22,700 189,400 (300) 10,900 72,200 128,800 5,300 23,800 347,300 245,000 175,000 571,600 8,300 5,600 87,100 3,000 888,900 301,400 55,700 155,300 45,300 10,400 12,600 1,513,700 243,400 42,500 161,300 1,410,500 59,000 148,900 21,400 1,027,500 12,000 31,000 23,600 19,200 380,200 $ 11,593,100 1 1 -1 ~i -1 -"I -1 -I -1 "1 1 1 | ""I ~"i 1 | "J ~8 I 1 1 8 1 8 1 1 8 8 8 8 1 8 1 1 I I I I V "I I I | 1 ] 1 1 I | 1 | CMA 030684 i FINANCIAL RESOURCES Each panel and council is required to maintain a CASH COMPENSATING BALANCE which recognizes that CMA signs all contracts on behalfofthe panels and counals. and assumes the financial HaMity for meeting their contractual commitments. The balance perm,ts timely honoring offinancial commitments. The combined compensating balance for all CHEMSTAR Panels and Councils at the beginning ofFiscal Year '90-91 was about $113 million On this date CMA had financial liabilities totalling about $6 million under 180 executed contracts on behalfofthe venous panels'. INTEREST on the unexpended cash balances provides supplemental revenue for each CHEMSTAR Panel and Council. This year, panels and counals earned a combined total ofapproximately $919 thousand in interest income EXPENDITURES ofCHEMSTAR Panels and Councils are based on budgets approved by each group. In Fiscal Year '90-91, panels and councils spent a collective total of$l0.8 million for research, consultants, legal counsel and panel/ council management CHEMSTAR PANELS AND COUNCILS Financial Allocations CMA 030685 Figure 2 CHEMSTAR PANELS AND COUNCILS Submissi ns t G vernment Agencies 400 r 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 Advocacy Planning: Chlorinated Pool Chemicals Panel CMA 030686 34 REGULATORY AFFAIRS During the year, 51 CHEMSTAR Panels focused their efforts on regulatory issues. Panels submitted comments on pending regulations, and research data, to many federal, state and international agencies. Of all federal agencies, EPA received the greatest attention from panels. TSCA Section 4 is the chiefconcern of 23 panels. The growth in environmental regulations ofindividual chemicals continued, causing increased panel focuses on the Clean Air Act in particular. Among other federal agencies, the Agency for Toxic Substances and Disease Registry, Food and Drug Administration, Occupational Safety and Health Administration, Mining Safety and Health Administration and the National Toxicology Program caused panel actions. Among state agencies, the California Department of Food and Agriculture attracted the most panel activity. This attention was due to Proposition 65 implementation and data call-ins on industrial chemicals. Reflecting the increased global focus ofthe industry, international agencies, especially the Organization for Economic Cooperation and Development, the United Nations Environment Programme, U.S. Department ofState, International Maritime Organization, and the Food and Agriculture Organization/World Health Organization were significant panel focuses. CHEMSTAR DIVISION StaffTime Allocations CAA 19% FI FRA 8% SDWA 4% SARA 2% TSCA 30% Other 5% States 6% OSHA 7% INTL 11% FDA 2% ATSDR 6% CMA 030687 Figure 4 CHEMSTAR PANELS Summary f Research Expenditures Epidemiology Environmental Toxicology Exposure Surveys Risk Assessment Atmospheric Clinical $220,000 $1,131,000 $4,228,000 $130,000 $114,000 $110,000 $100,000 Research Review: Alkylphenols and Ethoxylates Panel CMA 030688 RESEARCH Forty-five CHEMSTAR Panels sponsored some form of research. The trend this year was toward fewer, but larger projects. Health effects studies were a major focus. Toxicological research involved subchromdchronic, mutagenicity reproductive and developmental effects, oncogenicity and pharmacokinetic studies. Direct effects on humans were investigated by several panels through epidemiology and clinical research. Risk assessments and exposure surveys were other forms of research undertaken by nearly a quarter of all CHEMSTAR Panels. Environmental studies continued this year with larger budgets, reflecting greater interest in air and water regulations, in particular. Testing required under TSCA Section 4 was initiated by several CHEMSTAR Panels. Mainly, the tests are large-scale efforts lasting several years. The testing schemes include many decision points where EPA and industry scientists must interpret data and decide on next steps. As in the past, some Panels undertook studies simply because of research findings rather than direct regulatory concerns. "Proactive" research continues to be a significant part of CHEMSTAR Panels scientific efforts. Figure S CHEMSTAR DIVISION Summary of Contracts Managed CMA 030689 r GUIDANCE CHEMSTAR Policy Committee Purpose: The Committee ensures that ail CHEMSTAR Panels and Business Councils are conducted in a manner consistent with Association policy, and with the CHEMSTAR Guidelines; counsels with the panels and councils regarding new and revised operating needs; and, reviews and makes recommendations on advocacy activities when requested by a panel, council or staff. CHEMSTAR Policy Committee Chairman: Earnest W. Deavenport, Jr. Eastman Chemical Company Vice-Chairman: Ernest Drew Hoechst-Celanese Corporation Geraldine V. Cox Vice President- Technical Director CMA Gary C. Herrman Vice President-Treasurer CMA Staff Executive: Langley A. Spurlock Deputy Technical Director CHEMSTAR Division CMA 38 David F. Zoll V/ce President-General Counsel CMA CMA 030690 MANAGEMENT SERVICES As issues, objectives and locutions ofeffort multiply, monojement ofthe CHEMSTAR Pooe/s end Councils becomes ever moreaUMAaSA chalAleHn/griirntrgt f/f\oF*r panel, AcAouI AnAci/l mannJd ftaainsl>k sg.ro.u,kp _cl_h_a ir. men. _T_ his year, as in the past a broad array ' of CMA services were employed to ensure that panels and councils receive adequate support for the,r operations. Leadership Training The annual CHEMSTAR Leadership Ses sion uas held in [anuarv, and attended bv eight panel and council leaders. The Sessions are designed to assist chairmen in resolving the dilemmas of leading di verse and changing organizations. Ses sions are invitational, one-dav workshops primarily held tor new panel, council and task group chairmen Participation hv experienced chairmen also is welcome and sought. At the Sessions, a training specialist from a CMA member company provides advice on persuasive leader ship, and peers share experiences in deal ing with related problems. Because par ticipant ratings continue to be high, an other Session is planned for fall 1991. Communications Ensuring industry awareness of panel and council activities remained a high priority tor the CHEMSTAR Division. CHEMSTAR NEWS, a quarterly publica tion with a circulation of 1,900 is the Division's principal means of reaching a broad industry segment. The NEWS points out upcoming regulatory impacts on specific chemicals, summarizes recent actions of various panels and councils, lists panel and council reports and agency Above and Below Left; Leadership Sessions submissions, and highlights significant changes in panel and council member ship. Through the "Spotlight" article in each issue, the accomplishments of indi vidual panels and councils are summa rized. This year, the Hvdroquinone, Rub ber Additives, Fluorocarbon and Phenol Panels were featured. The CHEMSTAR Alerts, published as needed, are the Division's means of quickly informing panel and council members and others in the industry when a time-sensitive response is needed on a chemical-specific or a specific business interest issue. Subjects in Alerts vary from a pressing need to submit informa tion to an agency, to the need for joining other companies in a response to a regu latory deadline. In 1990-91, the Division issued two Alerts -- one on the' Interagency Testing Committee's 27th Report to the EPA; and the other on the OECD High Production Volume Existing Chemicals Testing Program. Division Staff The CHEMSTAR Division responded to this year's increase in panel and council activities by expanding the management staff and assigning new responsibilities to existing managers. Cecilia Spearing filled the newly created position of Senior Panel Manager, bringing the management staff to twelve persons, all with technical degrees. Kathleen Roberts and Bonnie Bailey also joined the staff as Panel Managers In CMA 030691 Director, CHEMSTAR Division Langley A. Spurlock, Fh.D., CAE Directors, CHEMSTAR Panels Hasmukh C. Shah, Ph.D., D.A.B.T. recognition of her superior achievements, Marian Stanley was promoted to Senior Panel Manager within the CHEMSTAR Division. In further recognition, at year's end, Lan gley Spurlock was promoted to CMA Assistant Vice President, Technical Ser vices Department and CHEMSTAR Divi sion Director. Legal Counsel The panels and councils were strongly assisted by the CMA Legal Department in antitrust, contract, research and regu latory areas. Reflecting the importance and complexity of their issues, a CMA attorney is assigned full-time to the af fairs of CHEMSTAR. To ensure that an titrust protection is consistently main tained, CMA attorneys counselled panel and council chairmen, as well as Division staff on proper procedures. As usual, staff attorneys reviewed all panel and council comments, contracts, reports, agendas, and minutes as part of routine protective measures. In research, the as signed CMA counsel intensively sup ported Division managers in drafting and negotiating the nearly 200 contracts awarded this year to laboratories and consultants. In advocacy, the CMA coun sel supervised the activities of outside counsels retained by the panels and coun cils. The CMA counsel provided advice on regulatory activities and ensured that member company legal counsels were informed of significant developments. Dr, Spurlock completed his ninth year as Director of the CHEMSTAR Division in June. He is responsible for oversight of all panels and councils. He also manages the Total Quality and Chemical Distributors Councils. Dr. Spurlock is a Certified Association Executive, awarded by the American So ciety of Association Executives. Before joining CMA, he held an appointment in the U.S. Government Senior Executive Service at the National Science Founda tion. During his tenure at NSF he served as Senior Staff Associate for Operations, Directorate for Mathematical and Physi cal Sciences, Special Assistant to the Di rector, Office of Planning and Resources Management, and as Oversight Coordi nator and Special Assistant to the Direc tor. Office of Audit and Oversight. Previ ously, Dr. Spurlock received an appoint ment as U.S. Department of Health, Education and Welfare Fellow, and served as Special Assistant in the Immediate Office of the Secretary of HEW. Earlier, he was Assistant to the President at the American Council on Education. Before coming to Washington, Dr. Spurlock held an appointment as Associate Professor of Chemistry at Brown University and ear lier was Assistant Professor of Chemistry at Temple University. Previously he served as Senior Research Chemist in the General Chemical and Agricultural Chemical Divisions of Allied Corpora tion. Dr. Spurlock received a Ph.D. in Organic Chemistry from Wayne State University."! Dr. Shah joined CMA and the CHEM STAR Division in 1979. He is responsible for the management of the Biocides, Brominated Flame Retardants, Ethylene Di chloride, and Vinyl Chloride Panels. Dr. Shah is a Board Certified Toxicolo gist. Before coming to CMA, he was the Director of the Toxicology and Biomedi cal Sciences Department of Equitable Environmental Health. He was also the Project Director for the National Institute for Occupational Safety and Health's cri teria document project, and for the "Pro files on Occupational Hazards for Crite ria Document Priorities." Previously, at the Stanford Research Institute, Dr. Shah was a Project Coordinator, and he served as a Senior Toxicologist. He also was a Visiting Fellow Scientist at the National Institute for Environmental Health Sci ences. Dr. Shah received a Ph.D. in Phar macology and Toxicology from the Uni versity of Rhode Island.^ CMA 03069 Carol R. Stack, Ph.D. Dr. Stack joined CMA and the CHEMSTAR Division in 1980. She is currently responsible for management of the pan els on benzene, chlorobenzenes, glycol ethers, and petroleum additives. Before joining CMA, Dr. Stack was em ployed m the Toxicology and Biomedical Sciences Department at Equitable Envi ronmental Health where she served as an Assistant Project Director responsible for the preparation of NIOSH multi-chemi cal criteria documents. Earlier, she served as Visiting Scientist at the Neurological Institute in Bogota, Colombia, where she investigated central auditory pathways in echolocatmg birds. Dr. Stack received a Ph.D, in Biology from New York Uni versity. 1 Associate Directors Elizabeth Festa Gormley, B.A. Ms. Festa Gormley joined CMA and the CHEMSTAR Division in 1983. She is re sponsible for the management of the Dibenzofurans/ Dibenzodioxins, Poly chlorinated Biphenyls, Hydrogen Fluo ride, and Crystalline Silica Panels, and the Atmospheric Research Council. Prior to joining CMA, she was Section Staff Executive with the National Electri cal Manufacturers Association, where she was responsible for the Nuclear Mag netic Resonance Imaging Section with the Diagnostic Imaging and Therapy Sys tems Division. Previously, Ms Festa Gormley worked in the Endocrine Bio chemistry section of the National Insti tute of Arthritis and Metabolic Disease at the National Institutes of Health, and held the position of Research Chemist at both CENTEC Corporation and Radian Cor poration. She was also a recipient of a National Science Foundation Assistantship. Ms. Festa Gormley earned a B.A. in Chemistry from Albertus Magnus Col lege.! Elizabeth J. Moran, Ph.D., D.A.B.T. Dr. Moran joined CMA and the CHEM STAR Division in 1981. She continued this year as manager of the Butadiene, Methylenedianilme, and Trimellitate Es ters Panels and the Laboratory and Re search Chemicals Council. Dr. Moran is a biochemist and Board Certified Toxicologist. She is currently on the Editorial Board of the Journal of Toxicology and Environmental Health, and on the Council of the American Col lege of Toxicology. She also chairs the ACT Committee on Animals in Research. Before coming to CMA, she was a pro gram manager at JRB Associates Earlier, Dr. Moran directed the Flavor Safety Pro gram at International Flavors and Fra grances, Inc., where she was responsible for toxicological testing on new chemi cals. Previously, Dr. Moran conducted lipid nutrition research at the U S. De partment of Agriculture and was a visit ing professor at the University of Mary land. Dr. Moran received a Ph.D. in Bio chemistry from the University of Mary land.! Robert R, Romano, Ph.D. Dr. Romano |oined CMA in 1980 as a manager in the Environmental Division where he was responsible for the water and air programs In February 1985, he joined the CHEMSTAR Division as an Associate Director, He continued this year as manager ot the panels on chlorine dioxide, ethylene dibromide, ethylene oxide, phosgene, water additives, and alkvlphenols and ethoxvlates. Dr. Romano came to CMA from the U.S. Nuclear Regulatory Commission, where he worked as an Associate Project Direc tor. Previously he worked on a school fluoridation project for the Indiana State Board of Health. He has also taught at Del Mar College and American Univer sity. Presently, Dr. Romano is an adjunct Environmental Engineering Professor at George Washington University and teaches courses in environmental man agement and program management. He received a Ph.D. in Environmental Sci ences and Engineering from Purdue Uni versity.! CMA 030693 Senior Panel Managers Jonathon Busch, MBA Mr. Busch joined CMA and the CHEMSTAR Division in April 1990. He is re sponsible for the management of the Car rier Assessment Council and panels on alkanolamines, cyclohexane, hydroquinone, titanium dioxide, and sodium bro mide. He also has been involved in activi ties of the Methyl Bromide, Fluoroalkenes, and Vinylidene Chloride Panels. Prior to joining CMA, Mr. Busch was a Senior Associate with 1CF-Clement,a health and environmental sciences con sulting firm. He was responsible for a variety of scientific efforts in toxicology, risk and exposure assessment, and envi ronmental auditing. Previously, Mr. Busch was Senior Science Analyst with the Cosmetic, Toiletry and Fragrance Association. He was responsible for de veloping scientific literature reviews on chemicals and for technical and adminis trative efforts associated with ensuring ingredient and product safety for the cos metic industry. Mr. Busch holds a MBA in Finance from George Mason University and a B.S. in Biology from Virginia Polytechnic Insti tute and State University.* "Ms. Francis joined CMA and the CHEM- Barbara O. Francis, MBA STAR Division staff in March 1989, She is responsible for the management of the panels on acetone, cumene, cresols, dinitrotoluenes, and ketones. Before joining CMA, Ms. Francis was with Interspan Inc., a management consulting firm. Previously, she held the position of product planner for Hoechst Celanese, Inc. and also served as a translator for the US Air Force in Europe. Ms. Francis holds an M.B.A. from Virginia Polytech nic Institute and State University and a B.S. in biology and chemistry from Bishop's University in Quebec, Canada." Susan R. Howe, M.S. Ms. Howe joined CMA and the CHEMSTAR Division staff in June 1989. She is responsible for the management of the Carbon Disulfide, Cobalt, Metal Catalysts, Nitrosamines, Oleylamine, Phenol, and Rubber Additives Panels. Mobay Corporation. Previously, she was a Regulatory Specialist with RuetgersNease Chemical Company. Ms. Howe holds an M.S. degree in Food Science and a B. A. in Science from the Pennsylvania State University.! Before coming to CMA, Ms, Howe was a Product Safety Representative for the "Ms. Spearing joined CMA and the CHEM- Cecilia W. Spearing, M.S. STAR Division staff as a Senior Panel Manager in the CHEMSTAR Division in January 1991. She is responsible for man agement of the panels on isopropanol, diisocvanates, and toluenediamines. When the next phases of the OECD Exist ing Chemicals Voluntary Testing Program are activated, she will manage a panel composed of U.S. companies that will sponsor testing. Before coming to CMA, Ms. Spearing was Project Coordinator, US Army Medi cal Research and Development Command Peer Review Panels, in the Special Sci- ence Programs Department ot the Ameri can Institute of Biological Sciences. Pre viously, she served as Staff Associate, Directorate for Mathematical and Physi cal Sciences, the National Science Foun dation. She also served the Foundation as Assistant and Associate Program Di rector, Metabolic Biology. Ms. Spearing holds a B.A. in Chemistry from Hunter College of New York. She received a M.A. in Science Education from Teachers College, Columbia University and M.S. in Biochemistry fromThe George Washington University School of Medi cine and Health Sciences." CMA 030694 Marian K. Stanley, MBA Ms. Stanley joined CMA and the CHEMSTAR Division staff in May 1990, She is responsible for the management of the panels on specialty acrylates /methacry lates and phthalate esters. Prior to joining CMA, Ms. Stanley was a Technical Project Manager with Squibbmark. Previously, she was em- ployed as both a development and ana lytical chemist at Union Carbide Corpo ration. Ms. Stanley holds an MBA in Pharmaceu tical Studies from Fairleigh Dickinson University, and a B.S. in Chemistry from Pratt Institute.! Panel Managers Bonnie Bailey, M.S. Ms. Bailey joined CMA and the CHEMSTAR Division staff in November 1990. She is responsible for the management of the Methyl Bromide, Sodium Bromide, Butylated Hydroxytoluene, Hydrazine, and Oxo Process Panels. Prior to joining CMA, Ms. Bailey was an environmental analyst with Technology Applications, Inc. Ms. Bailey holds a B.S. in Microbiology from American University, and is com pleting a M.S. in Environmental Science from George Mason University.! ^Vls. Roberts joined CMA and the CHEM- Kathleen Roberts, B.S, STAR Division in April 1991. She is re sponsible for the management of the pan els on ethylene glycol, fluoroalkenes, chlo rinated pool chemicals, hexamethylene diisocyanate, ethylene dichloride, and vinylidene chloride. She also manages the Fuels Detergent Performance Task Group under the Petroleum Additives Panel. Prior to joining CMA, Ms. Roberts was Product Manager withJellinek, Schwartz, Connolly & Freshman, an environmental consulting firm. In the firm's Pesticide Reregistration Division, she managed several pesticide testing programs re quired under FIFRA. Previously, Ms, Roberts was a laboratory technician for Hazleton Laboratories America, conduct ing genetic and inhalation toxicology studies. Ms. Roberts received a B.S. degree in Biology from the University of North Carolina at Chapel Hill.! Counsel Robert D. Ondocsin, J.D. Mr. Ondocsin became Counsel to the CHEMSTAR Division in 1991. Mr. Ondocsin reviews and provides coun sel in production of all substantive panel and council documents including con tracts, regulatory comments, legislative correspondence and testimony, filings in litigation, and press releases. In addition, he advises panels and councils on anti trust issues and manages retained coun sel. Mr. Ondocsin joined the CMA Legal De partment in 1989 as Counsel for OSHA matters including hazard communica tion, worker notification, employee medi cal, health and safety programs, and rightto-know. Before coming to CMA, Mr. Ondocsin was an Industrial Hygienist with Union Carbide Corporation in the Chemicals and Plastics Group. He also held a simi lar position at PPG Industries, Inc. He holds a B.S. and an M.S. from the Univer sity of Pittsburgh, and a J.D. from Pace University.! CMA 030695 DIVISION STAFF From loft to rightr Hasmukh Shah, Elizabeth Moran, Ronnie Bailey, Susan Howe, Marian Stanley, Langley Spurlock, Robert Romano, Barbara Francis, Jonathon Busch, Elizabeth Gormley, Cecilia Spearing, Kathleen Roberts, and Carol Stack. CMA 030696