Study Title ORAL (GAVAGE) TWO-GENERATION (ONE LITTER PER GENERATION) REPRODUCTION STUDY OF AMMONIUM PERFLUOROOCTANOATE (APFO) IN RATS SPONSOR'S STUDY NUMBER: T-6889.6 Data Requirement U.S.

PiR11-OM30 CO RN ING Hazleton MUTAGENICITY TEST ON T-6564 IN AN IN VIVO MOUSE MICRONUCLEUS ASSAY FINAL REPORT AUTHOR Hemalatha Murli, Ph.D.

Me thod : uKB/OO -tOOOOOO .USKRb^JUb'.srtILEXZJDt'2Eu00o Component: ET-C8 Date: IO-SEP-1991 14:47:07.30 Quadratic fit KO: 1.5256E-03 Kl: 1.9351E+00 K2: -5.8485E-01 Inter nal standar d SO o e f f . of determination: l.QOuo AR226-2416 Standard Sample STD v n STD X 1.5 STD X 1 STD X 0.3 STD X 0.1 Corapone nt Area 17683b5 1366427 949132 493292 101357 Btandar-d Area 2147347 2121692 2121968 2098421 2121787 Component Hass 2.0000 1.5000 1.0000 0.50000 0.10000 Standard Mass 4.0000 4.0000 4.0000 4.0000 4.0000 Standard Sample STD X 2 STD X 1.5 STD X I STD X 0.5 STD X 0.1 Area Ratio 0.82351 0.64403 0.44731 0.23746 4.805E-02 Mass Ratio 0.50000 0.37500 0.25000 0.12500 2.5000E-2

AR226-2541 RESPONSE TO INFORMATION REQUESTED REGARDING APRIL 1992 VI REPORT (REFERENCE; EPA REGION III LETTER DATED MAT 5, 1997) DUPONT WASHINGTON WORKS WVD045875291 Responses to information requested in the referenced EPA letter are presented below.

TRADE SECRET DuPont HL-1997-00735 AR226-3077 Study Title H-22762: Eye Irritation Test in Rabbits Laboratory Project ED: HL-1997-00735 Author: Carol Finlay, B.A.

M~ A C U TE TO X IC ITY TO A Q U A TIC IN VER TEB R A TES (DAPHNIA MAGNA) T E S T SU B STA N CE______________________ _ _ ____________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFO S, FC-95, or as a component of FC-203CE. (1Octanesulfonic acid) (C A S # 2795-39-3).

A f t 2 6 - 01&2> TOXICITY TO AQUATIC PLANTS TEST SUBSTANCE________________________________________________ Identity: Mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203CF-X or FC-203CF. (1-Octanesulfonic acid) (CAS # 2795-39-3).

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| @HAZLETON WASHINGTON AR226-0%5] GENOTOXICITY TEST ON T-5710.1 IN THE IN VIVO/IN VITRO UNSCHEDULED DNA SYNTHESIS AND CELL PROLIFERATION IN RAT LIVER CELLS [EINAL REPORT AUTHOR Maria A.

AR 226 _ 0731 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (ACARTIA TONSA) IESTSUBSTANCE 00 Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203. (1- Octanesulfonic acid) (CAS # 2795-39-3).

BACK TO MAIN Battelle Field Sampling Procedures Review Columbus Georgia City Survey regarding Empirical Human Exposure Assessment Multi-City Study To Susan Beach - Project Lead 3M, ET & SS PO Box 33331 Building 2-33-09 St.

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TRADE SECRET AR226-3182 DuPont-6711 Study Title Jff^ Acute Oral Toxicity Fixed Dose Method Laboratory Project ID: DuPont-6711 TEST GUIDELINE: OECD Guidelines for Testing of Chemicals Section 4: Health Effects, No. 420 (1992) AUTHOR: Carol Finlay, B.A.