IN VITRO MICROBIOLOGICAL MUTAGENICITY ASSAYS OF 3M COMPANY'S COMPOUND T-3610 Final Report September 1984 By: / O j u ^ i i L L Debra E.

AR2X-032 To : Study Files of Riker Experiments Nos. 068QTR0008 0680TR0010 0680TR0020 0681TR0095 0681TR0110 0680RR0018 From: U.

Pathology and Toxicology Riker Laboratories, Inc.

A R A S 6 _ 071 & ' BIODEGRADATION (OECD 301E) TEST SUBSTANCE_______________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203. (1Octanesulfonic acid) (CAS # 2795-39-3).

R*082 REV. i*<J cstaiushio hoi E. [ . du Pont de;ncNorpeo*mato( ours & C o m pany Wilm ington.

Monsanto From (Name-Location-Phone) Diane G.

Monsanto ------------------------------------------------------------------------------------------------------------------------------- DEPARTMENT OF MEDICINE A ENVIRONMENTAL HEALTH Monsanto Company 800 N.

A Morbidity Study of Former Pentachlorophenol-production Workers Daniel O.

ecWe AUG i 9 j8 * BttflU ,CRITERIA FOR IDENTIFYING AND CLASSIFYING CARCINOGENS MUTAGENS AND TERATOGENS Developed Jointly by: An international Working Party of Experts, Organized Under the Auspices of the Safety of Chemicals Committee of CEFIC the International Affairs Group of CMA/SOCMA and Canadian Chemical Producers Association August 21, 1985 AP00055034 August 21, 1985 CRITERIA FOR IDENTIFYING AND CLASSIFYING CARCINOGENS, MUTAGENS AND TERATOGENS Developed Jointly by: An International Working Party of Experts, Organized Under the Auspices of the Safety of Chemicals Committee of CEFIC the International Affairs Group of CMA/SOCMA and CCPA* INTRODUCTION A tripartite group of industrial experts, from Europe, Canada and the United States, dealing with toxicology, epidemiology and chemical classification, has developed a set of working documents offering consistent guidance for identifying and classifying carcinogens, mutagens, and teratogens* These documents represent an attempt t:o: 1) harmonize principles in the hazard identifica tion of carcinogenic, mutagenic, and teratogenic substances; 2) provide guidance for the purpose of judging relevant data, on a weight of evidence approach; and 3) serve as a constructive factor in discussions with authorities when differences in respective regulations are an issue.

MR J* products Organization Announcement 14 July 1986 TO: All Managers FROM: R.

Submitted 7/13/81 8/13/81 9/1/81 9/18/81 9/22/81 11/23 81 12/1/81 Document Comments of chemical Manufacturers Association on Occupational Health Hazards of Toxic Chemicals in Laboratories, 46 FR 21785, April 14, 1981.

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DANIEL B.