Second, one microgram of lead in air produces two micrograms of lead in blood (the so-called air lead/blood lead ratio).

The gasoline lead coefficient in regressions of blood-lead levels on that variable, adjusted for observed covariates, has been used to quantify the causal effect of gasoline lead on blood-lead levels.

The second is the trend in the incidence of children with elevated blood lead levels and lead poisoning levels.

Metabolism of Lead.....................................

As reported earlier, the primary finding of this paper is that blood lead air lead relationship, alpha, varies with blood lead level and air lead concentration.

Lead readily crosses the placenta, producing an increase in blood lead levels in the fetus.

Lead appears in food from the solder used on cans; in water from the lead pipes used in older plumbing; and in air from lead addi tives used in gasoline, from the dust of dd lead paint and putty, and from the initial smelting of lead ore that makes lead available for ail its uses.

Ethyl was correctly concerned with exposure to lead in food and the possible contribution of lead In gasoline to exposure by this mode.

To do this I repeated the gasoline lead regressions, and used them to remove the variance due to gasoline lead exposure, which is about 85% of air lead exposure.

Applying the blood lead/air lead slope J>f 2 m /dl to the estimated national air lead drop of 0.32 pg/nr, provides a rough estimate of 0.64 pg/dl for the expected blood lead drop.

The references on lead exposure are subdivided into two groups; (1) Adult and (2) Children air lead - blood lead relationships.

Lead on the children's hands (PbH) was also significantly related to lead in air or lead in dust.

It is not clear how the blood lead value from this relationship relates to any blood lead percentiles at a given air-lead value.

Victery (1982) found lead associated with a significant elevation of blood pressure in rats with blood lead levels of 41 ug/dl.

Quantitative Evaluation of Lead and Biochemical Indices of Lead Exposure in Physiological Media......................... ............................................. .