L-805 MANUFACTURING CHEMISTS ASSOCIATION MINUTES OF MEETING LABELS AND PRECAUTIONARY INFORMATION COMMITTEE STOUFFER'S NATIONAL CENTER HOTEL Arlington, Virginia January 28, 1976 Mr.

Such roundabout procedure is certain to lead to interminable delays at best, and at worst an eventual terminal blow to the use of vinyls in this market.

In workers exposed to high levels of VC. hepatic fibrosis associated with or leading to portal hypertension and angiosarcoma of the loer has been described.1 Vinyl chloride disease has also been associated with dermal induration, aero-osteolysis, splenomegaly and thrombocytopenia/J In animals.

FILE NAME Brakes BRK DATE 1979 DOC BRK072 DOCUMENT DESCRIPTION Journal Article - Survey of Asbestos Workers in the UK - NY Academy of Sciences 4, SURVEILLANCE OF HIGH GROUPS SURVEY OF ASBESTOS WORKERS THE PRESENT POSITION IN THE UNITED KINGDOM W.

The contents, prepared by author-gardener Joan Kirk, have been reviewed by leading botanists, entomologists and horticulturalists.

Work is inprogress at the Fire Research Station to study the production oftoxic gases when plastics materials are decompos ed under controlled laboratory conditions involving pyrolysis at temperatures up to 1000`C and in fullscale tires using a special compartment with a variable ventilation slit (door) leading to a corridor.

Heavy metals such as lead, arssnic, mer cury, copper, antimony, zinc, selenium, end cadmium occur naturally in water and some soils, but usually in trace amounts that present no hazard to human health.

This leads to two types of disease.

/ 9 NATIONAL EMISSION STANDARD FOR VINYL CHLORIDE \ COMMENTS -BY THE / HEALTH COMMITTEE POLYVINYL CHLORIDE SAFETY GROUP " THE SOCIETY OF THE PLASTICS INDUSTRY, INC.

/ UC 149-2 ^ I (j] jf ~ ~ * lld'bc INTERNAL CORRESPONDENCE UNION CARBIDE CORPORATION 270 PARK AVENUE, NEW YORK, NEW YORK 10017 To (Name) Division Location ^ p- Larrison Union Carbide Corporation Mining & Metals Division P. 0.

FILE NAME Quebec Asbestos Mining Association QAMA DATE 1979 June DOC QAMA159 DOCUMENT DESCRIPTION QAMA Bulletin Vol 3 No. 3 IRDA One of the principal recommendations of the Sor^sgroup to whom the Association des mines d'amiante du Qu^'bechad conferred the task of carrying out an indepth study of the possibilities of manufacturing asbestos products in Qu^'bec brought out the necessity of intensifying rsearch and development Sor^sreport In order to develop new asbestosbased products and fill a widening gap in the research and development between these products and their substitutes the Sor^s report concluded positive and drastic actions should be taken to improve the prospects of growth of asbestos and asbestos products where an intensive research and deve- lopment program should be launched in the shorter delays with the following objectives ) to improve the characteristics and the perception of existing asbestosbased products ii to improve the manufacturing pro- cesses to develop new asbestos products and manufacturing processes These actions could be carried out by an existing organization or by a new organization to be created grouping all the interested decision centers Government policy While the Sor^s experts were com- pleting the preparation of their report the Qu^'becgovernment announced its new asbestos policy proposing the creation of a research and development cen- tre for the development of new asbestosbased products on the one hand and for research into ways and means of ensuring health and safety in both the manu- facture and the use of asbestos products on the other making specific recommendations for the operating and financing of a research The government expressed the wish that such a centre might be created jointly with the industry which would have the primary responsibility for orienting and organizing the proposed research body The AMAQ having already endorsed the recommendation of the Sor^sreport which had been commissioned well be- centre The CDT report was a valuable working document enabling the AMAQ and its member companies to make a constructive and enlightened contribution based on expert objective analyses towards the establishment of a research and development organization fore the government announced its policy had no hesitation in subscribing to the objectives put forward by the government regarding research and development and immediately offered its col- laboration AMAQ draft agreement Thus in October the AMAQ was able to take action on the agreement in principle signed the previous month by the Minister of Natural Resources and the Directors of the Association at the Plan of action However neither the statement of government policy nor the Sor^sreport went beyond formulating general objec- tives It was still necessary to determine the possibilities and means for speeding up the process of developing research into asbestos in Qu^'becso that the best possible performance is obtained in viable economic conditions by making optimum use of the human material and technological resources available It was also necessary to ascertain the major needs and objectives for asbestos research and development in first joint meeting on the subject and offer the government a draft agreement covering the principal objectives together with details concerning the establishment operation and financing of a new centre For the most part it is this draft agreement with just a few minor changes which was the object of an order in council dated June 6 1979 and which forms the basis of the agreement for the creation of the Institut de recherche et de IRDA Minister d^'veloppement de l'amiante signed June 29 1979 by the of Natural Resources and the President of the AMAQ Qu^'becand to draw up a concrete plan of action for the creation of a centre Finalization The AMAQ welcomes the finalization CDT study of this agreement by virtue of which the project can now enter the phase of active The AMAQ therefore commissioned a study from the Centre de d^'veloppement technologique CDT of the Ecole Polytechnique de Montr^'alwith a view to making a survey of all asbestos research activities to assessing the possibilities and limitations regarding their development in Qu^'becand to organization The incorporation and organization of the IRDA will be taken in hand by the AMAQ which will moreover provide the entire 500 000 starting capital the creation of the institut ushers in a dynamic and stimulating period for asbestos research and development in Qu^'bec LBulletin| Pilot study to be carried out by Qu^'becscientists A research project sponsored by the Institute of Occupational and Environmental Health of Montr^'al The Institute of Occupational and Band director of the clinical re- Environmental Health recently ap- search unit at the Institut du Cancer proved an important research pro- de Montr^'aland Dr.

FILE NAME Brakes BRK DATE 1979 DOC BRK305 DOCUMENT DESCRIPTION Survey of Asbestos Workers in the UK 1979 4, SURVEILLANCE OF HIGH GROUPS SURVEY OF ASBESTOS WORKERS THE PRESENT POSITION IN THE UNITED KINGDOM W.

This will lead to an increase in the level of reactive metabolites and result in an increased reaction of these metabolites with intracellular macromolecules.

Our programs toward this end include investigations of the fundamental mechanisms leading to resin adherence to polymerizer surfaces and a wide variety of methods aimed at eliminating adherence, chemically and/or mech

VC 5.0-^P/P%V -UL a.5) School of Medicine Department of Medicine Division of Digestive Diseases and Nutrition University of Louisville Health Sciences Center April 6, 1979 Louisville, Ky. 40232 P.O.