This supporting data will be a prerequisite to meaningful comments on costs and lead time required to comply with this proposal.

The major contin gency which is expected to lead to the high of the range is a broadening of the use of asbestos in cement products.

In advanced stages this leads to an interhepatic block (most like ly because of the hinderances in the height of the portal system, possibly similar to a sinusoidal block), with esophagus varices.

The factors leading to fire tox tims with burns and 39 percent of the vic tims without bums).

The use of asbestos substitutes may also lead to cost increases in the manu facture of patching compounds.

Metabolism of drugs by this enzyme system leads sometimes to more active and toxic compounds which produce liver in jury, e.g., in the case of carbon tetrachloride.

On the other hand, unlike the asbestos workers, a large proportion of the male subjects was employed in sedentary occupations iavojyiflg little or no physical exertion; and lack of exercise is associated with increased risk ofcoronary heart disease--the leading cause of death among males in the United Slates.

In an effort to insure the replenishment and growth of this vital source, the chemical industry took an early lead in constructive concern for education.

r &S 105617 DOW CHEMICAL U.S.A. 21 September 1977 MIDLAND.

VC 5.0-ZDP/P/^eV -ul School of Medicine Department of Medicine Division of Digestive Diseases and Nutrition University of Louisville Health Sciences Center April 6, 1979 Louisville, Kf. 40232 P.O.

AIR PRODUCTS & CHEMICALS INC.

PRESTONE anti-freeze, one of Union Carbide's best-known products, has been the leading brand on the market for 45 years.

5: i 1971 (1930). .

JOSEPH E KELLEB JEBOME H HECKMAN CHABLES M MEEHAN WILLIAM H BOBOHE5ANI JR HOBEHT B TIBHNAN WaYNB V BLACK DAVID L HILL MAHTIN W BEHCOVJCI PETES M.

TABLE 1 Common Components of Automotive Brake Linincs0 Binder and organic friction modifiers Fiber reinforcer Property modifier Phenolic-type resin Rubber I ire scrap Pitch Cork Gilsonite Cashew nutshell resin and particles Drying oils Chrysotile asbestos6 (grades 4--7) Unaltered Calcined Mixed fiber Lead compounds Zinc compounds Antimony oxide Iron oxide Copper metal Brass chips Clay minerals Barite (BaSO.,) Wollastonite (CaSiO:!)