Fleck Ethyl Corporation 100 Park Avenue New York City 17 Dear Van: In reply to ycur letter of April 16 on the subject of the possibility and desirability of Ethyl's consenting to an increase in the concentration of tetraethyl lead 'in motor gasoline above the present conventional level of J> cubic centimeters of tetraethyl lead per American gallon of gaso line, I have this to say. 1.

Fleck Ethyl Corporation 100 Park Avenue New York City 17 Dear Van: In reply to ycur letter of April 16 on the subject of the possibility and desirability of E t h y l 's consenting to an Increase in the concentration of tetraethyl lead `in motor gasoline above the present conventional level of 5 cubic centimeters of tetraethyl lead per American gallon of gaso line, I have this to say. 1.

Lead for Urmrt. lead for gasufme, lead for jnotregion agAtfift thr rlnzamts. lead M a cmstruction mate* nl-thr*r are only a few of die many applications th*t Hitr brm found fur Wad. which have demon* strsted proven economic uahlona fba MaonMf af Tafroafhyi M I do ant feel qualified to discuss in detail the *e> fulnrsa of other Uacheuosuming products, but t can trC vou a little about what trtiartfayl Wad has come lo taraa to our national economy. 1 rnmrntmmmmmmm ; LlAl6<, 3l ' la dm thirty year* since it wot war >m--s laurjs introduced, tetn*<byi lead has come to be used 'uWw over 953 of all motor and aviatioa gasolines, because of this fact tetraethyl Wad has grown to become the second largest consumer of metallic lead In the country.

Lead for Urmrt. lead for gasufme, lead for jnotregion agAtfift thr rlnzamts. lead M a cmstruction mate* nl-thr*r are only a few of die many applications th*t Hitr brm found fur Wad. which have demon* strsted proven economic uahlona fba MaonMf af Tafroafhyi M I do ant feel qualified to discuss in detail the *e> fulnrsa of other Uacheuosuming products, but t can trC vou a little about what trtiartfayl Wad has come lo taraa to our national economy. 1 rnmrntmmmmmmm ; LlAl6<, 3l ' la dm thirty year* since it wot war >m--s laurjs introduced, tetn*<byi lead has come to be used 'uWw over 953 of all motor and aviatioa gasolines, because of this fact tetraethyl Wad has grown to become the second largest consumer of metallic lead In the country.

If their results continue to be favorable we may be approached in the not too distant future for supplies of tetraethyl lead, and I would like to be able to give them some sort of an answer.

It has come to my attention that we paid a death claim on September 22nd in which the cause of death was ascribed to tetraethyl lead.

You will remember that a considerable amount of work was done years ago on the distribution of lead in the organism following the absorption of tetraethyl lead.

Moreover, the vola tility of the lead compound is so lov, as compared with that of the gasoline, that only insignificant and practically un measurable amounts of tetraethyl lead appear in the vapor over- lying leaded gasoline.

Moreover, the vola tility of the lead compound is so lov, as compared with that of the gasoline, that only insignificant and practically im measurable amounts of tetraethyl lead appear in the vapor over lying leaded gasoline.

Is that the mask might be flooded and might, therefore, become quite inactive in taking tetraethyl lead out of the air.

Kettering Laboratory University of Cincinnati Eden and Bethesda Avenues Cincinnati 19, Ohio Dear Bob: Thanks mightily for your comment on the tetraethyl lead manuscript.

The thing we have been most fearful of, in dealing with situations In which men might be exposed to high concentrations of tetraethyl lead, particularly in association with gasoline vapors, Is that the mask might be flooded and might, therefore, become quite inactive in taking tetraethyl lead out of the air.

The necropsy findings wsr compatible with the clinical diagnosis above, and in fact, except for certain unrelated chronic lesions, resembled those described in certain previous fatal cases of lead poisoning* The terminal broncho pneumonia, for example, has been described In such oases before, (Sorris and Settlor, J.A.M.A. 8*5: 8l8, (1925)* with the results of analysis, are listed below, and are compared with the average results obtained by this laboratory on normal parsons, as well as those obtained in a previous fatal case of tetraethyl lead poisoning.

Also the evidence Is adequate to demonstrate that in the commercial concentrations in gasoline, tetraethyl lead is not absorbed out of the gasoline through the skin.

'tetraethyl lead, on the other hand, really is absorbed rapidly, as are also some other ?