.10 employment through retirement or resignation, eventually, ail but a small number of these were accounted (or as either living or dead, and in the latter event, the cause of death was substantiated in a similar manner, and the results added to the original list of deaths.

1958 Sational Safety Congress Milkr Equipment Co., Inc, Franklin, Pa.

J

PUBLICIZING SAFETY licity and public relations Never ex aggerate Underplay instead of over play, if you have to make a choice 2 Deliver what you promise If you say in your news release that something is going to happen, make certain it hap pens--and as you said it would 3 If for any reason there is a change in plans from what you have announced in your releases, notify the papers and ra dio and TV stations at once 4 Be scrupulously accurate m your names, places, and other facts There is no such thing as being too careful m this respect Get a reputation for sloppy, inaccurate reporting of your facts, and you are through 5 Cover up nothing if the news is bad Prove to press representatives and the public that you can roll with the punches 6 Be reasonable in your requests for space and time 7 Be the same with the amount of ma terial you send out You can wear out your welcome 8 Do not put out anything unless you have real news or features to offer You must not issue materia!

UTILITIES DEPARTMENT APPROVED SAFE WORK PROCEDURE TEST FOR SILICA Procedure No.

URL 19744 VINYL CHLORIDE--i-/vtCiNOGENESIS 79 the concept that the hepatocytc's ability to resist cancer transformation is dependent upon its ability to detoxify the mutagenic/carcinogenic metabolite of vinyl chloride.

co: Mr.

THE DIGESTIVE AND GENITAL CANCER MORTALITY EXPERIENCE OF MONSANTO-INDIAN ORCHARD PLANT EMPLOYEES SUMMARY A proportional mortality analysis of the death certificates of 564 former Monsanto-Indian Orchard plant employees revealed a marginal excess, though not statistically significant, in the number of deaths from digestive and genital cancer.

PROTECTED MATERIAL ]NSANTO INSURANCE COVERAGE LITIGATION -l Texas City '\ C, E.

TELEPHONE NATIONAL t - 2388 Manufacturing Chenlist$, Association, Inc.

i nUFBONB NATIONAL I-23M Mmufacturing Chemists' Association, Inc (POUNDED 1872) 246 Woodward Building -- 15th and H Sts, N.

Oct. 16, 1951 (59) MINUTES of the twelfth meeting of Directors of the Manufacturing Chemists' Association, Inc., held at The Uni n Chib, Park Avenue and 69th Street, New York City, on October 9, 1951, at 11:00 a, m There were present: Messrs.

TABLE 42-A COMBINED TABULATION OF TOXICITY CLASSES Commonly Used Term LDW Single Oral Dose for Bats (gmlkg) 4-hr Vapor Exposure Causing 2 to 4 Deaths tn 6-Rat Group (ppm) LD$o Skin for Rabbits (gmlkg) Probable Lethal Dose for Man Extremely toxic Highly toxic Moderately toxic Slightly toxic Practically nontoxic Relatively harmless 0 001 or less 0 001 to 0 05 0 05 to 0 5 0 5 to 5 0 5 0 to 15 0 More than 15 0 Less than 10 10 to 100 100 to 1,000 1,000 to 10,000 10,000 to 100,000 More than 100,000 0 005 or less 0 005 to 0 043 0 044 to 0 340 0 35 to 2 81 2 82 to 22 6 More than 22 6 Taste (1 grain) 1 tsp (4cc) 1 02 (30 gm) 1 pint (250 gm) 1 quart More than 1 quart Fwm Handbook of Toxcolog>, Vo/ J, Acute Toxictties ' W S Spector,ed Philadelphia, 1956 W B Sounder* Co axioms form the basis for experimental tox icology Although they appear self evident they are not susceptible to rigid proof 1 Any substance contacting or entering the body will be injurious at some degree of exposure and will be tolerated without effect at some lower exposure 2 The nature of the injuries which may de velop in men can be determined by the study of the reactions of experimental animals 3 It is possible to define an exposure to animals that has no effect upon its health Health and well-being, however, are not measurable It is the injury that is meas ured 4 From animal experiments, the degree of exposure that will not affect humans can be determined Experimental toxicology has done well for human safety by allowing regulation of ex posure m accord with the results of animal experiments The first attempts in estimating the toxicity of a substance are usually made on the basis of animal experiments Data from these ex periments is expressed as lethal doses (LD) in milligrams of substance per kilogram of body weight of the test animal The most commonly used expressions are these 1 MLD -- minimum lethal dose, the smallest dose which kills one of a group of test animals 2 LDm-- lethal dose for 50 per cent, the dose which kills one-half of a group of test ani mals (usually 10 or more) 3 LD,oo--lethal dose for 100 per cent, the dose which kills all of a group of test ani mals (usually 10 or more) These doses may also be expressed as lethal concentrations (LC) for airborne toxic substances Substances can then be rated according to their relative toxicity as shown in animal ex periments, and the probable lethal dose for humans can be estimated (See Table 42-A These ratings are based on the results of 1305

Now York 16, New York Dear Hugh: At tho tirno of our Annual Mooting you and I dlueuaocd the status of the ATI study, and I promised to sand you material which might be help ful. 1 realize that you -viL1 not be uainj; It until January or February, but thought 1 would send you what wo turned up immediately. '.V e will continue to search and will a end you anything more that we find before tnc time of your meeting. hr the American Journal of Medicino for November 1953, Iuaelbachcr, Klaus, and Hardy have an article entitled, "Aiboitosi.i and broncho genic Carcinoma".

^TlaIntIffs^ EXHIBIT I I | JM 552 I Rhodesian Asbestos Limited Temeraire & Shamafa Mines, and Temeraire Mill AAashaba, Southern Rhodesia.