V -:V .` .* -iJr, ' : * V ;' V i the tetraethyl lead industry, especially as developed in the last five years and in the light of my better knowledge of the subject.

v- , the tetraethyl lead industry, especially as developed in the last five years and in the light of my better knowledge of the subject.

Storage facilities are included for Sodium, Ethyl-Chloride, EthyleneDibroralde, Ethylene-Dlchlorlde, Kerosene, Acetone, Lead, and Tetraethyl Lead.

August 7 1957 Dr# 0 lU Weaver Duval County Hospital Jacksonville Florida Dear Doctor Weavers have just heard by a somewhat eiroultous route that you have seen a case \ihIch you believe to be lead poisoning In a man oho is said to have washed a truck (presumably with leaded gasoline)* 'he patlentfs nano was Over a period of some years* my associates and 1 have been studying the problem of load absorption in relation to leaded gasoline* and we have investigated directly or indirectly all cases of alleged lead poisoning that have been reported to us through various channels* I might say* parenthetically* that we have been unable to find any oases of poisoning or any etldeaee which would lead us to believe that load poisoning is possible as a consequence of contact* even over long periods of time* with gasoline containing tetraethyl lead* However wo are still on the lookout for such oases* and 1 should appreciate It very deeply* therefore* if you would report to me In the self-addressed stamped envelops* your findings in this case* together with all of the pertinent facts as to exposure and the patient's occupation* Moreover* if there is anything which we can do by way of investigation or laboratory determinations which would tend to substantiate or clarify the diagnosis in tills case* 1 should be pleased to do so.

Since such compounds as tetraethyl lead, lead acetate and lead oleate are readily absorbed through the skin, we are prone to question this character istic of the two compounds in question.

Since such compounds as tetraethyl lead, lead acetate and lead oleate are readily absorbed through the skin, we are prone to question this character istic of the two compounds in question.

How many cubic eontimeterr> of tetraethyl 1 .

However, they felt that we might want to be informed of this be cause of this doctor* 3 having blamed tetraethyl lead for the man * s condition.

However, they felt that we slight want to be informed of this be cause of this doctor*3 having blamed tetraethyl lead for the man*s condition.

' Considerable time was spent in discussing the toxicity aspects of the mixed alkyls, I pointed out that we had obtained data showing that the use of tetramethyl lead would result in lead concentrations up to 40 times as great as would obtain with tetraethyl under the same conditions.

I cannot but wonder what is the situation in Russia with respect to the use of tetraethyl lead, as well as in the manufacture of tetraethyl lead and the prepara- tidn'of leaded' gasoline.'

You are further right when you indicate that such lead as was present did not seem to be tetraethyl lead.

We have a movie of several patients with tetraethyl lead encephalopathy, but still photographs would show nothing, and this would be true of other types of lead encephalopathy, as, for example, that of children which represent the only type of lead encephalopathy which is seen frequently in these days.

The lethal do-sages and concentrations are of the order (somewhat less) of tetraethyl lead.

Two gasolines, with and without lead tetraethyl, will be used.