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Regulation (EC) No. 1907/2006 (REACH) Proposal for a restriction of Per- and polyfluoroalkyl substances (PFASs) submitted by BAuA - Federal Institute for Occupational Safety and Health Bureau REACH, National Institute for Public Health and the Environment (RIVM) Swedish Chemicals Agency (KEMI) Norwegian Environment Agency The Danish Environmental Protection Agency Date: 07.02.2023 22 March 2023 Dear Sir or Madam, We welcome the opportunity to contribute to the public consultation initiated by the European Chemicals Agency regarding potential restriction of Per- and polyfluoroalkyl substances (PFASs) according to Regulation (EC) No. 1907/2006 ("REACH").

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Annex XV Restriction Report Proposal for a restriction for per- and polyfluoroalkyl substances ("PFASs") Submission to the public consultation "Overlapping of PFAS substances already regulated or in the process of being regulated in other restrictions" Chemours Belgium B.V.

TNO-report of study 3M-02 PFAS in ApoE3Leiden mic Final report CONFIDENTIAL TNO-report T h e e f f e c t o f 3 P e r f l u o r in a t e d A lk y l SULPHONATED ON CHOLESTEROL/BlLE ACID METABOLISM IN 1 5 % -F A T FED E 3 -L E ID E N T r a n s g e n ic m ic e In Viv o a n d o n f a t t y a c id CONVERSION INTO CHOLESTEROL IN RAT h e p a t o c y t e s In Vit r o .

ARI2G-OHOY MICROBICS MICROTOX TOXICITY TEST TEST SUBSTANCE Identity: Perfluorooctanesulfonylamido(ethyl)acetate; may also be referred to as PFOSAA, FC-128 or as the major component of eFtCh-y1l2-7N-,[(FhCe-p1ta2d8e,caFfCl-u1or0o9o,ctFyCl)-s1u0l9fo-nXylo]r-,R1p9o0t4a.ssi(Gulmycsialnte,, N- CAS # 2991-517) Remarks: The test sample is FC-129 referred to by the test laboratory as R1904.

/ ft m -o M 0 5 BIODEGRADATION TEST SUBSTANCE Identity: Perfluorooctanesulfonylamido(ethyl)acetate; may also be referred to as PFOSAA, FC-128 or as the major component of FC-127, FC-129, FC-109, FC-109-X or R1904.

ACTIVATED SLUDGE RESPIRATION INHIBITION TEST SUBSTANCE Identity: rPeefrefrlrueodrotoocatsanPeFsuOlSfAoAny,laFmCi-d1o(2e8thoyr)aascetthaetem;ajmoarycaolmspoobneent of FC-127, FC-129, FC-109, FC-109-X or R1904.

/ ft m -o M 0 5 BIODEGRADATION TEST SUBSTANCE Identity: Perfluorooctanesulfonylamido(ethyl)acetate; may also be referred to as PFOSAA, FC-128 or as the major component of FC-127, FC-129, FC-109, FC-109-X or R1904.

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General Comments We welcome the opportunity to contribute to the public consultation initiated by the European Chemicals Agency (ECHA) regarding potential restriction of Per- and polyfluoroalkyl substances (PFAS) according to Regulation (EC) No. 1907/2006 ("REACH").

Where needs take us Safety data sheet According to 1907/2006/EC (REACH), 453/2010/EU, 2015/830/EU Phos-Chek 3% AFFF MS - [AQUAFILM AF-3MS] 1.1 Product identifier: Phos-Chek 3% AFFF MS - [AQUAFILM AF-3MS] 1.2 Relevant identified uses of the substance or mixture and uses advised against: Relevant uses: Fire-extinguishing.

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