LIFE SAFETY DISTRIBUTION GmbH Z.A.

Classification: Public Merck Healthcare KGaA 64293 Darmstadt Germany Additional Information on Missing Uses with regard to the ANNEX XV Restriction Report on Per- and polyfluoroalkyl substances (PFASs) as published by ECHA on March 22nd, 2023 Content Use Sector...................................................................................... 2 Information on Uses Covered in the Annex XV Report ............................ 2 EU Approved Active Pharmaceutical Ingredients ................................. 2 F-Gases....................................................................................... 2 Information on Uses Not Covered in the Annex XV Report (Missing Uses) . 2 Medicinal Products ........................................................................ 2 Fluoropolymers in Industrial Use ..................................................... 4 Starting Materials, Reagents, Intermediates, Solvents, Auxiliaries ......... 5 Active Pharmaceutical Ingredients in Development Products ................ 6 Immediate Packaging of Injectable Medicinal Products ........................ 7 Medical Devices ............................................................................ 8 Conclusion ................................................................................... 8 2 Merck Healthcare KGaA Classification: Public Use Sector Merck Healthcare KGaA is one of the three business sectors of Merck KGaA.

Input to Public Consultation on PFAS restriction proposal On behalf of Contact information Version Continental AG Vahrenwalder Strae 9, 30165 Hannover Germany Head of Group Hazardous Substances Management No. 1 Internal Continental AG Continental develops pioneering technologies and services for sustainable and connected mobility of people and their goods.

PolyPhotonics Berlin e.

CEGIS Health.

Assogomma comments on the Annex XV Dossier of the universal PFAS restriction proposal September, 6th 2023 1 1.

Alliance Froid Climatisation Environnement Partenaire de la filire pour une utilisation responsable des fluides frigorignes 22 septembre 2023 RPONSE DE L'AFCE LA CONSULTATION PUBLIQUE SUR LA PROPOSITION DE RESTRICTION GLOBALE DES PFAS Notre industrie est une histoire russie d'innovation : limination progressive des gaz fluors appauvrissant la couche d'ozone (CFC, HCFC) dans les annes 1990 et transition vers les gaz fluors avec un potentiel de rchauffement plantaire (PRP) de plus en plus faible depuis 2010.

Refineries and distribution PFAS uses Refineries and distribution - Gaskets, tubes, inline of pipes/tanksRefineries and distribution - Wires and capacitors Refineries and distribution - Switchgears Refineries and distribution - Converter Valves Refineries and distribution - High Voltage DC Heat exchanger Power transformers - Cooling liquid Refineries and distribution - Oil and gas transport and storage equipment Refineries and distribution - Lining of piping, flowmeters and fittings, compensator joints, fluid-handling components, process Refineries and distribution - Flexible risers and flowlines Refineries and distribution - Valve bodies Refineries and distribution - Valve packing Refineries and distribution - Valve seals, elastic tubes Refineries and distribution - O-rings Refineries and distribution - Pipe gaskets Refineries and distribution - Capacitive sensors and their connecting cables Refineries and distribution - Ball valves, Refineries and distribution - Fluid transfer equipment Refineries and distribution - Flexible pipes Refineries and distribution - Filtration equipment (e.g., HEPA filters - a synthetic composite with `expanded' PTFE membrane) Refineries and distribution - Vibration dampers Refineries and distribution - Pneumatic actuators, pneumatic regulating devices Refineries and distribution - Pump liners Refineries and distribution - Dispensers, nozzles, compressors Refineries and distribution - Heat exchangers Refineries and distribution - Cables insulation Professional apparel - PPE for industrial and professional use (Refineries and distribution than sportswear) Refineries and distribution PPE - (non-medical) - Safety helmets Refineries and distribution PPE - - (non-medical) - Gloves Refineries and distribution PPE -- (non-medical) - Eye protection Refineries and distribution PPE - (non-medical) - Hazmat suits Refineries and distribution PPE- High-visibility clothing Refineries and distribution PPE - Safety footwear Refineries and distribution PPE - Safety harnesses Refineries and distribution PPE - Ear plugs Refineries and distribution PPE - Ear defenders Refineries and distribution PPE- Respiratory protective equipment Refrigeration - Industrial refrigeration Refineries and distribution Air conditioning and heat pumps - Stationary air conditioning and heat pumps Refineries and distribution Refrigeration and heat pumps - Industrial refrigeration Refineries and distribution Foam-blowing agents - Rigid polyurethane spray foam Refineries and distribution Refrigeration and heat pumps - Heat pumps - Steam production Refineries and distribution - Lubrications of screws, nuts, magnetic anchors, bolts etc.

Comment regarding the impact on reuse and recycling of construction- and demolition waste For several years, there has been a focus on promoting the circular agenda, including the reuse/recycling of construction and demolition waste.

Processed product for water supply and sewerage applications Application :Water supply and sewerage Materials used in the field are PTFE (CAS NO: 9002-84-0), PCTFE (CAS NO: 9002-839), PFA (CAS NO: 26655-00-5), PVDF (CAS NO: 24937-79-9), and ETFE (CAS NO: 94228-79-2).

Comment on Proposed Restriction of PFAS May 25, 2023 Japan Fluoropolymers Industry Association (JFIA) We, Japan Fluoropolymers Industry Association (JFIA), think that fluoropolymers should be distinguished from the proposed restriction of PFAS (Per- and polyfluoroalkyl substances), which collectively regulates more than 10,000 of organofluorine compounds (PFAS) on the grouping basis.

GLP COMPLIANT LABORATORIES Chilworth Technology the experts in process safety Chilworth Technology Ltd Beta House Southampton Science Park Southampton SO16 7NS UK Tel: 0722 Fax: 7866 Web: www.chilworth.co.uk Email: Mchilworth.co.uk Digital Documentation Chilworth Technology Limited.

PFAS PUBLIC CONSULTATION: BRIEF PLASTIC ENERGY STORAGE SYSTEMS Brussels, 25 September 2023 EuPC is the leading EU-level Trade Association, based in Brussels, representing European Plastics Converters.

ECHA PFAS Annex XV Response Derogation for Electronics and semiconductors, Annex E.2.11, Electronics and Semiconductors: Annex XV claims: "Sufficiently strong evidence that technically feasible alternatives exist for heat transfer fluids for immersion cooling" and as conclusion: "High substitution potential at EiF for heat transfer fluids for immersion cooling {sufficiently strong evidence] and liquid crystal displays [weak evidence]".

CECHA EUROPEAN CHEMICALS AGENCY Eurofeu Secretariat General KoellikerstraBe 13 97070 Wurzburg GERMANY MPeurofeu.org 1 (6) Helsinki, 12 February 2021 ECHA's firefighting foams restriction proposal: questions related to the use of firefighting foams Dear Sir/Madam, The European Chemicals Agency (ECHA) is currently investigating the use of per- and polyfluoroalkyl substances (PFAS) in fire-fighting foams1,2.