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AR226-3209 TRADE SECRET Study Title H-23926: Biopersistence Screening 10-Dose Oral Gavage Study in Rats Supplement No. 1 Laboratory Project ID: DuPont-2920 AUTHOR: Carol Finlay, B.A.

ra_z 32e 54 "eo TRADE SECRET ARAZ6_ 3254 DuPonc11111 Study Title H-25357: Acute Eye lritation Study in Rabbits Laboratory Project ID: DuPont-11111 TEST GUIDELINES: U.S.

i 7AR226-1307-3 AE {DEi INEE a vo 170s LCeTe ve ANTS i) "AL ne Tbehg _-- al (aes atti ah \i RA id be 3 dr XE ee iy :J. : . 0) 9/70) 3 a ' Elg || po iFS | | 1!

" I PFOS: An ActivatedSludge, RespirationInhibitioTnest Ii i L'.

PathologAyssociateisnfernational A Company ofScienceApplicationisntemationCaolrporation An &rp"v*.O~ CopwV PATHOLOGY REPORT (ANCILLARY STUDY) ELECTRON MICROSCOPIC EVALUA17ION OF LIVER IN CYNOMOLGUS MONKEYS 26-WEEK CAPSULE TOMCrrY STUDY WITH PERFLUOROOCTANE SUIXONIC ACED POTASSIUM SALT (PFOS,-,T-6295I)N CYNOMOLGUS MONKEYS CLIENT STUDY'NUMBER 6329-223 PAI STUDY NUM33ER EM 99.76 Prepared by: James B.

Protocol.PFOS: A 7-D (Lemna gibbaG3) PROTOCOL PFOS: A 7-DAY TOMCrrY TEST WrrH DUCKWEED (LemnagibbaG3) U.S.EnvironmentaPlrotectioAngency Series850 -EcologicaElffectsTestGuidehm OPPTS Nunber $50.4400 3M Lab RequestNo.

ri A,) MECHANISOMF'TOXICITOYF 'AUNIQUEPESTICIDE.t-: ETHYLPERFLUORDOCTANE SULFONAMIDE (NEPFOS)- Alff ITS METABOLITE PERFLUOROOCTANE (PFOS) TO ISOLATED RABBIT RENAL CORTICAL MITI:@.

3M ModbW Departfnent L%cNdno Huft Physics IndustW Hygiene ToxkmiM 3M CerterBldg.220-2E-02 SL PaulM,N 55144-1000 612f7331110 Analyticaanld ResearcPhroperti-e3sM IndustriHsydgienelabomtory January1993 Scope Thisisa methodforthedeterminatoifoNn-EthyPlerfluorooctanesulfonamide in air.

oral Terstoloa Study of T-2999C*C in RALbbits Zxperiment No.: Gonducted At: Dosing Period: Study Director: 06SITBO212 Safety Zvaluation Laboratory Fikex 'fa ratorl", Inc* ft.

ACTIVATED SLUDGE RESPIRATION INHIBITION TEST SUBSTANCE Identity:Perfluorooctanoiaccid,ammonium salt;may alsobe referredtoas PFOA ammonium saltA,mmonium perfluorooctanoateP,FO, FC116, FC-126, FC-169,or FC-1 43.

ACUTE AQUATIC TOXICITY TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may also be referredtoas PFOS, FC-95, or as a component of FC-203. (1Octanesulfoniaccid)(CAS # 2795-39-3).

ACUTE TOXICITY TO FISH (MUMMICHOG) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may also be referredto as PFOS, FC-95, or as a component of FC-203. (1Octanesulfonicacid)(CAS # 2795-39-3).

READY BIODEGRADATION (OECD 301E) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonawthei,ch may alsobe referretdoas PFOS, FC-95,or as a component ofFC-203CE. (1Octanesulfoniaccid)(CAS # 2795-39-3).

BIODEGRADATION (BOD/COD) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatew,hich may also be referredto as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonicacid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-,potassium salt,CAS # 2795-39-3) Remarks: The 3M productionlotnumber was not noted.