2. vi.v i^u J.UKX uor. uti.L.j.

SPONSOR ElfAtochemSA.

AR226-3024 fc .

AR226-3045 Study!

AR226-3125 HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE H-24119: STATIC, ACUTE 96-HOUR SCREENING TEST TO FATHEAD MINNOWS, Pirn ephales promelas PURPOSE: This is a rangefmdmg study designed to provide an estimate of aquatic toxicity using fixed test concentrations and data measurements at predetermined intervals.

SPONSOR ElfAtochemS.A.

AR226-3181 TRADE SECRET Testing Guidelines International Conference on Harmonisation (ICH) of Technical Requirements for Registration ofPharmaceuticals for Human Use.

AR226-3202 TRADE SECRET Study Title H-25134: Acute Dermal Irritation/Corrosion Study in Rabbits Laboratory Project ID: DuPont-8778 TEST GUIDELINES: OECD Guidelines for Testing of Chemicals Section 4: Health Effects, No. 404 (1992) Commission Directive 92/69/EEC EEC Method B.4 (1992) AUTHOR: Carol Finlay, B.A.

ARaRE _ 3255 isd `TRADE SECRET ARaR6_ 3258 Duront11269 Study Tide H-25357: Oral Approximate Lethal Dose (ALD) in Rats Laboratory Project ID: DuPont-11269 AUTHOR: Carol Finlay, B.A.

AR226-1741 Toxicological Summary PFOS Dietary Chronic Definitive Reproductive Study: Mallard Test Substance: Perfluorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro, potassium salt.

PFOS: A Se Cladoceran(( .

Acute Toxicityt PFOS) ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity:PerfluorooctanesulfonatDeE,A salt;may alsobe referredto as PFOS DEA salt,FC-99, or 3M Sample No. 2. (1-Octanesulfonic acid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafcloumoprdo.-, with2,2'-iminobis[ethan(o1l:]1),CAS # 70225-14-8) Remarks: Test sample isa mixtureofthe testsubstanceinwater (approximatel2y5% testsubstance and 75% water).Allvaluesreported relatetothismixture.No calculationwsere made to adjustforthe actual concentrationofthe testsubstance inthe testsample.

COMPOSITE ANALYTICAL LABORATORY REPORT ON THE QuantitativeAnalysisof Fluorochemicalsin Environmental Samples REPORT No.

ti'704 17.(*00 PROJECT N@l, " 3M TIECTINICA@ NOMOOK 1 Subjcct: JOACCLAf"lAlckj@oh OkFM-34-2-L Ckomm-st .. i- ,, A Object: ...

REPORT AMENDMENT NO. 1 TWO YEAR ORAL (DIET) TOXICITYICARCINOGENICITY STUDY OF FLUOROCHEMICAL FM-3924 IN RATS Experiment No.0281CROO12 The attachedpages include revisions in the first paragraph on page 3 of the Summary and in the third paragraph of page 22 of the Discussion.