ARRA6 - SYSk --_ 58 --_ --_ 000466 "0 Cope, we | | | "Dc s A && + AR 226 - SUSY 1904 0m-so8e pesrs 5(ooh) k=woy =2 22fa0 2==20 2w0n 2a 3M(apn) ax100 0wn oao0 FEFEYy 2Pay b 8 B= 1ao "waw & i a I m 200 #008 = wI anSaoco ki1ni2o00 ETay =50 300 = w=o. 02000 3o%n aonoo =2on0 a0io0 =m= aooo outr&o ppsearysts Pusz=ra a2seoizssas0aesg SSizeer S222222m001 Gotz J1e9a5ir]y a= pa oSoene SHpiroe S=e=er ppprreay 2p2mrg SS2auosmezaenn nproemd --~@) 000467 1 LE = Wg EOE = rd .

P. 1 36z1 PERFLUOROOCTANE SULFONATE (PFOS) Dossier prepared in support for a nomination of PFOS to the UN-ECE LRTAP Protocol and the Stockholm Convention The dossier is prepared by the Swedish Chemicals Inspectorate (Keml) and the Swedish EPA, Sweden August 2004 000288 p2 Preliminary Risk Profile PFOS 2 25 June 2004 000289 p. 3 Prelimina ry Risk Profile PFO S Contents EXECUTIVE SUMMARY .....................................................................................................4 INTRODUCTION .................................................................................................................... 6 PART I.

425 Walnut Street, Taft/ Taft Stettinius & Hollister LLP Suite 1800 / Cincinnati, OH 45202-3957 /Tel : 513 .381 .2838 / Fax : 513 .381~0205 /vvww .taftlaw .com Cincinnati / Cleveland / Columbus / Dayton / Indianapolis / Nortrhern Kentucky / Phoenix / Beijing ROBERT A BtLoTT 513.357.9638 bilott@tafdaw.com 14 1 aa6-38'29 February 16, 2009 F r:r-c9-$-cro 15 7T TSCA Confidential Business Information Center (7407M) EPA East - Room 6428, Attn: Section 8(e) & FYI U .S.

Taft/ 425 Wanut set, Site1800/Cncmnats ON 45202-3957 Tt:!

ST-508 Final Report ToxDocs 14-192 TOXICOLOGY ASSESSMENT AND COMPLIANCE ASSURANCE GROUP 3M COMPANY 14-192: ORAL ADME STUDY OF MTDID 37312 IN RATS FINAL REPORT ToxDocs Study Number 14-192 Test Material Lot Number(s) Strategic Tox Lab Study Number MTDID 37312 FM-3923, mixture of lots 30035, 30037, and 30039 ST-508 Other Identification Number(s) N-EtFOSE Alcohol, FC-10 19F/1H-NMR Analytical Report SMD Analytical Report 816 GID Number Study Director Jill Hart, AAS, LATg Senior Laboratory Technologist Principle Investigator: (Study Monitor) Sue Chang, Ph.D.

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ARZ2G -00%6 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (E.G.

FE-RO ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: aPPceFirdOf,lSu1o,Dr1oE,o2Ac,t2s.aa3nl,et3,s,uF4lC,f4-o,9n59a,,t5e,o,6r,D63,EM7A,7S,saa8lm,t8p;,l8me-ahNyeop.atla2ds.eocba(fe1l-urOoecrftoea-rn,reescduoltfmoopnadis.c: with 2,2"iminobislethanol] (1:1), CAS # 70225-14-8) R(aepmparrokxism:atTeelsyt2s5am%ptleestissaubmsitxatnucree oafndth7e5te%stwastuebrs).tanAclevianlwuaetserreported relate to this mixture.

a - ARIG-Oles kbw-2398 _ Effect of N-Alkyl Perfluorooctylsulfonamides on Mitochondrial ~~ Bioenergetics In Vitro i Kendall B.

$f rIGINAL marsorr | JRAE-0993 Sty Tie Toxicokinetic Study ofPerfluorooctane Sulfonamide (PFOSA; T-7132. 2) in Rats Authors AnTdoxriecwolMo.gySeSapceactiaPlhis.tD. 3M Medical Department, Corporate Toxicology Deanna J.

KSatHherVineeiReneh PAD. | 86HQ.0501 - 0373 n3Md: ESneviyonSmerevniacelsTechnology y 9B00 Buash Aa ve 423199 73 ASPOorBotxPM33N31Sst 2 " 6a7M oo orate A AR R26 - 1016 CDoEcRuTmIeFntIEPrDocMeAssIiLng Cee 7407) (Attn: Section 8(c) Coordinator) OUfSfiEcneovifroTnomxeinctSaulbPsrtoatneccetsion Agency 4W0a1shMingSttroene,t,DSCW20460 Tian "ontain No cB RSuel:foTnaStCe,Apo(ta)ssNiOuTmIsCalE, FCoAr:S#Ac2u7t9e5-T3o0x-i3city Honey Bee Studies on Perfluorooctane Dear Sir: 3T0o4ctiasnseusbumliftotniincgatchied,re1su1l,t2s 2f,r3o,m3r,e4c,en4t,5or,a5l,a6n,d6c,o,n7t.ac8t,8ac,u8t-ehteopxitcaidtey cptaeofstsiasupsoeirruofmo-rsmaeltd (wCitAhS pNeor.f2o7r0m5e:d39b.y3C)e-ntcroammScoinelnycereLfaebrorreadtorya5(PCSFLO)S, S-aonndhHountetyonbeYeso.rkTYhOe4t1wo1sLtZu,diUeKs.were "oTbhseercvoinntgacthteobxieceistyfotres9t6inhovuorlsv.edThpaeinretsiunlgtsthoeftbheiessswtiutdhyvsahrioowusthcaotntcheent9r6athioounrsoCfonPtaFcOtS and Liig3y5J)0o)aw.nadstU5hn0ed.ce7lramsbesoi/tfKhicgtahtoeifocnbloassdcsyhifewimeceaitgfihootrn t(sh4ce.h7Ie8nmiteegmdbaeetvieeo)lnoawplietCdhobmaymNiAOstksEiiLnoosnfefto2ar4l.B11e9em7g7B/o)Kt(gacno(yn1t(a9Ic3tCCB) (1985) (oral and contact, ths contact LDSO would be classified as "moderately toxic".

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AR2ac_ 1130 a = 3g wr UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, D.C. 20480 2 = 23 or 17 a mu_-- m w5e Des nterestd Pry Bon aaanion ni Toes (OPP.

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AR ARG -- IKE FLUOROCSHTEAMTUISCALRSEVIIENWBLOOD : =s/22719, BG e ooJnrognaMgnaciyhca3i0f,niup1o9er7ro8fc,laurob3roMonsinsifunorrfbmal:codeo-dDauctoifPvoeentmmpalotfoeyrefieiasnldsie.nxgpsosoefdantoic : lfaloiutaohdroilrdneeevmebillssowtosdeolrervdeuelsst.sof--ag1ensteowrsia7tt1oehpdop-cpmwewreiearrteaie-oifntnos-u-rnewadhn.eodgrfee"Hioher 4f8lu-o8r1ipnpem,in h3uMmarnesporitssaptphaatrenstomley tnorramcael,levie.el. oflesosrgatnhiacn 1 ppm.