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AR226-1742 PFOS: A PILOT REPRODUCTION STUDY WITH THE MALLARD FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

BACK TO MAIN ACCUMULATION OF PERFLUOROOCTANESULFONATE AND RELATED FLUOROCHEMICALS IN MARINE MAMMALS John P.

BACK TO MAIN 3M Company EPI-0013 Page 1 of 5 INTERIM REPORT Epidemiology Medical Department 3M Company St.

Toxicological Summary PFOS Dietary Chronic Pilot Reproductive Study: Mallard Test Substance: Perfluorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoropotassium salt, CAS# 2795-39-3 Test Remarks: The test substance is a white powder (3M Lot #217).

AR226-2338 Fluoropolymers Monitoring Technical Group September 18, 2003 Agenda Program Overview - EPA Suggested Priority Change Discussion Landfills Soil Sampling Biota Sampling ssy ^E^y-^sl Possible Sources of Exposure PFO Impuri POSF R Mate Trans formation to PFOA APFO Manufacture w '< Fluoropolymer Summary Processing Fluoropolymer Manufacture Dry Resin Processing Non Fluoropolymer Products Aqueous Resin Processing APFO Manufacture 99% Reduction in emissions as compared to prior manufacture Air dispersion modeling Water monitoring - Prior Manufacturer - New technology baseline Program Plant Design LOI LOI/other LOI Timi In pl Com Ongo Ongo >99% Emissions Reduction APFO Manufacture Air Dispersion Modeling Water Monitoring LOI ECA Fluoropolymer Summary Processing Fluoropolymer Manufacture Non Fluoropolymer Products Dry Resin Processing Aqueous Resin Processing Non-Fluoropolymer Products Program Tim Commitment to not sell APFO outside fluoropolymer industry LOI Ong I 3s O, hrMi -- ID M m H 0 W M I-' 01 >99% Emissions Reduction APFO Manufacture Air Dispersion Modeling Water Monitoring Fluoropolymer Summary Processing Fluoropolymer Manufacture Dry Resin Processing Aqueous Resin Processing LOI ECA Fluoropolymer Manufacture Global Material Balance 50% Emissions Reduction Commitment 2002 Status - 48% reduction from the baseline Monitoring/Modeling Commitments - Air dispersion modeling - Groundwater - Soil - Landfill Program pre-LOl pre-LOl LOI LOI/other Other Other Timi Com 20 12/31 Ongo (Toda (Toda >99% Emissions Reduction APFO Manufacture Air Dispersion Modeling Water Monitoring LOI ECA Fluoropolymer Summary >50% Emissions Reduction Fluoropolymer Manufacture j-^ Dispersiola tVtodeling ^vVater Sampliing/ ^vionitormg ^/-<^n^--S^\ ------------------11 T31,,-N^/.1n^<' Processmg -> Dry Resin Processing Aqueous -> Resin -> Processing ------------------------k- W 0 I.J M H CT 0 w C.I 10 ^ aSu M CO I-' 0 W M It Processing/Articles of Commerce Program Tim Articles of commerce testing - "New" Articles of Commerce - "Aged" Articles of Commerce Dispersion processors material balance Incineration testing LOI ECA LOI ECA 12/3 200 12/3 6/30 >99% Emissions Reduction APFO Manufacture Air Dispersion Modeling Water Monitoring LOI ECA Fluoropolymer Summary >50% Emissions Reduction ^ Fluoropolymer Manufacture ^\ir Disperstoii ^viodeling \ Water Samplung/ 3v\ ionitoring ^C^S ^ ^Ton 1 k Processing ~> Dry Resin Processing Aqueous -+ Resin -^ Processing Articles of Commerce Tes Dispersion Processors Mat Aged Articles of Commer Incineration Testing sl a s s ro o ^ EPA Proposal Delay "Articles of Commerce" testing and goal date and accelerate "Air dispersion modeling" at Fluoropolym manufacturing sites in order to expedite the process to determine if additional monitoring (and ECA) is need these facilities.

TRADE SECRET AR226-3165 DuPont-2926 Study Title H-24002: Biopersistence Screening 10-Dose Oral Gavage Study in Rats Laboratory Project ID: DuPont-2926 AUTHOR: Carol Finlay, B.A.

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3M ComPpagaeny| FINAL REPORT EpiMdeedmiicoalloDgye,pa2r2t0m-e3nWt-05 3M Company St.

.. 3M StLaafrfryViRc.eZParbeels,enMtD, MPH and Medica Director 3M Medical Department AR226-0002 P3OMBCeonxte3r3,2B2u0ilding 220-2502 S6t5.1P7a3u3l 5M1N815O5f1f3i3c-e3220 April 20, 2000 Dr.

FO on 1 WZ FYTI-o0500- 1378 UNITED STATES ENVIRONMENTAL WASHINGTON, D.C.

PR226-0225 3M Environmental Laboratory Final Report- Analytical Study Single-Dose Dermal Absorption/Toxicity Study of T-6051 and T-6054 in Rabbits In-Vivo Study Reference Number: HWI#6329-133 TSetsutdySuNbusmtbanecre:: AFMCD-T12-901(3T1-96055.11 and T-6054) `Name and Address of Sponsor: 3M SCD Division 367 Grove Street St.

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71pp Ann K.