H-24921: Dermal Sensitizatfon Test - Buehler Method AR226-2804 DuPont-7977 TRADE SECRET STUDY TITLE H-24921: Dermal Sensitization Test - Buehler Method LABORATORY PROJECT IDENTIFICATION DuPont-7977 PSL Study Number 11321 Work Request Numbet----^J Service Code Numberfatf) DATA REQUIREMENT U.S.

AR226-3184 DuPont-4739 TRADE SECRET Study Title H-24616: Subchronic Toxicity 90-Day Gavage Study in Rats with One-Generation Reproduction Evaluations Volume 1 of 5 Laboratory Project ED: DuPont-4739 TEST GUIDELINES: U.S.

FINAL REPORT PROTOCOL 418-013 ORAL (GAVAGE) PHARMACOKINETIC STUDY OF PFOS IN RATS SPONSOR'S STUDY NUMBER: T-6295.12 FINAL REPORT DATE: 24 JUNE 1999 PROTOCOL 418-013 ORAL (GAVAGE) PHARMACOKINETIC STUDY OF PFOS IN RATS SPONSOR'S STUDY NUMBER: T-6295.12 TABLE OF CONTENTS SUBJECT 1.

'"-'@'HAZLEMON WASHINGTON 9200 LEESBURG PI6 KE VIENNA, VA.22 1 82 1 99 ANALYSIS OF T-5878 IN A CELL PROLIFERATION ASSAY IN RAT LIVER CELLS L FINAL REPORT AUTHOR Maria A.

ACUTE TOXICITY TO AQUATIC INVERTEBRATES (E.G.

CAS Number 423-82-5 3M Company VoluntaryUse and Exposure InformationProfile N-ethylperfluorooetylsulfonamido ethyl acrylate 1.

NITRIFICATION INHIBITION TEST SUBSTANCE Identity:Mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredto as PFOS, FC-95, oras a component of FC-203CF-X or FC-203CF.

PFOS: A 48-HOUR STATIC ACUTE TOXICITY TEST "WITH THE CLADOCERAN (Daphnia magna) FINAL REPORT `WILDLIFE INTERNATIONAL LTD.

@HAZLETON reTy"N \ 016% ) J Z NS i ANALYSIS OF T-5794 IN A CELL PROLIFERATION ASSAY IN RAT LIVER CELLS AR26-0302 [EINAL REPORT AUTHOR Maria A.

Al226-/548 Toxicological Summary Pros Dietary Acute Northern Bobwhite Study `Test Substance: Perfluorooctanesulfonate (PFOS) Structure: Remarks: METHODS poaium sah CASH 2795.335 |-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8.8,8-heptadecafluoro-, Trhedtesutndsuebrsatamnbceitis caownhdiitoenspoawndderur(GM wlats#o2r1g7i)nallTyhedrsammpilnedwa1s pleas be 90.49% byutp LCMS, 'H-HMR, riploiglon ""F-NMR and elemental analyses dCeotnecremninaeidontso ibnehi8s6s.u9%m.marTyhaersnvoamsienaolnatned 8m5e3as%urpeudrtydiveatatrey PFOS vTahleueis nbafsedphoanseherep0o.rt40wa%spourrgtiynaelsltyractoimopnletTeheinre2po0r0t0,waasndrrieepodrted 3008 to rflt the subsent revision. in ample purty This Toxicological Summary reflects these changes as well as including results from all of the associated reports of analyses of tissues collected during the in-life phase.

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AR226-2449 tiT"'/^ HEERC AT A1 AT EU01S2 r'1" '" 09/17/97 03:57 PM 3i To: cc: Subject: BRANDERA AT A1 AT EU01S2 .

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PathologAyssociateisnfernational A Company ofScienceApplicationisntemationCaolrporation An &rp"v*.O~ CopwV PATHOLOGY REPORT (ANCILLARY STUDY) ELECTRON MICROSCOPIC EVALUA17ION OF LIVER IN CYNOMOLGUS MONKEYS 26-WEEK CAPSULE TOMCrrY STUDY WITH PERFLUOROOCTANE SUIXONIC ACED POTASSIUM SALT (PFOS,-,T-6295I)N CYNOMOLGUS MONKEYS CLIENT STUDY'NUMBER 6329-223 PAI STUDY NUM33ER EM 99.76 Prepared by: James B.