P. 1 DuPont-18318 TRADE SECRE T Study Title Ammonium Perfluorooctanoate : 28-Day Immunotoxicity Study in Male Mice TEST GUIDELINES : U .S .

_ AR126-0095 PFOS: A 96-HOUR STATIC ACUTE TOXICITY TEST WITH `THE SALTWATER MYSID (Mysidopsis bahia) FINAL REPORT WILDLIFE INTEMRNLAATBIROENLQTAUDLE,STPRNOOJ,E3C7T3N3UMBER: 4504-101 ScrUS150EOamPliTnoSeeNnusmtbeEPror8s5i0o1T0no3A5Ggearienes AuORS at Dror HenrOy.

SBCcoroEtsAi HetiIt.S tn 608.241.4471 608.241.7227 Fax AR260322 CORNINGHazleton 3M St.

EERIE Corporate Occupadonsl Medicine 3M Cer Building 220-3W.05 51733 906 Fox nRa96-0YTY aM 6O.ccAunpaEtpiiodneamlioElxopgoiscurIenvteostPiegraftliuoonroofocRteapnrooidcuAcctiidve Hormones in Men with "This published paper by Olsen et al (J Occup Env Med 1998;40:614-622) further examined the observation initially reported by Gilliland in his doctoral thesis that serum PFOA levels (as measured by total organic fluorine) may be associated with reproductive hormone changes.

AR 226 - 0707 BIODEGRADATION (BOD/COD) EST SUBSTANCE Identity: ArefmeirxrteudretocaonstPaiFnOiSng,pFeCr-f9l5u,oroorocatsanaescuolmfponoanteen,twohficFhC-m2a0y1Fa-lXs.o b(e1Octanesulfonic acid) (CAS # 2795-38-3). 2R0e1mFa-rXks(:F-111T2h9)e. 3MCuprrroednutctinifoonrlmoattniounmibnedriwcaatses 1i.tiTshaemtiexsttusraem3p%lePiFsOFSC,S3o6d%iudimeotchtyyllesnuelfgaltyec,ol6b%utsyulleftohneart,ed36a.lk6y%l ewtahteerr,sa8l.ts2,53%%actrryileicthfaonaomlearm,in7e,%and 0.15% toluoltriazole. cThhaerafcotlelrowiiznegdscounmcmeantrryataipopnlsioesftiompaumriitxiteusr.eDiattha imnacyomnpoltetaeclcyurately reflect the biodegradabilityof the fluorochemical componentofthe test sample.

AR 226 - 0862 BIODEGRADATION (BOD/COD) TEST SUBSTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referredto as PFOS, FC-95, or as a component of FC-603F. (1Octanesulfonic acid) (CAS # 2795-39-3).

BACK TO MAIN MICROBICS' MICROTOX TOXICITY TEST TEST SUBSTANCE Identity: Perfluorooctanoic acid, tetrabutylammonium salt; may also be referred to as PFOA tetrabutylammonium salt, tetrabutylammonium perfluorooctanoate, N2803-2, or as a major component of L -13492.

AR226-2449 tiT"'/^ HEERC AT A1 AT EU01S2 r'1" '" 09/17/97 03:57 PM 3i To: cc: Subject: BRANDERA AT A1 AT EU01S2 .

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SPONSOR ElfAtochemS.A.

Summary PFOS Rat Two-GenerationReproductionStudy StudyNumbers:3M T-6295.9,Argus418-008(in-lifFeA)C,T-TOX-012 (analytical).

'"tiAZLEMON W A S H IN G T 0 N 9200 LEESBURG PIKE VIENNA.

CAS Number 376-14-7 3M Company Voluntary Use and Exposure Information Profile N-ethyl perfluorooetanesulfonamido ethyl methacrylate 1.

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:Mixturecontainingperfluorooctanesulfonawtheich may alsobe referredto as PFOS, FC-95, or as a component of FC-203FC. (1Octanesulfoniaccid)(CAS # 2795-39-3).

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