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TCDD; PCDF-- AS CONTAMINANT Acute Symptoms Headache Nausea, Vomiting Respiratory Skin Irritation Eye Chlorinated Naphthalenes Acute Yellow Atrophy of Liver C07496

LAW OFFICES WILLIAMS 8 CONNOLLY 725 TWELFTH STREET, N.W.

Environmental Events OSHA Noise Control Management Course.

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7* ^ l ( p : KETTERING LABORATORY BUSINESS O FFICE U N IV ER SITY OF CINCINNATI * M AIL LOCATION 5 - w CIN CIN N ATI.

Monsanto Fred D.

ZACK-GAFFEY REPORT DEATHS IN EXCESS OF EXPECTED CAUSE * Lung cancer Genitourinary cancer Bladder cancer ** Lymphatic cancer *** Other sites **** All cancers Heart disease NUMBER 10 2 2 3 2 18 27 PERCENTAGE OF DEATHS HIGHER THAN EXPECTED 143% higher 108% higher /V 809%,/higher' 92% 'TTigher 26% higher 43% higher 37% higher * Four deaths omitted from Zack-Gaffey Report -- ** Completely omitted from Zack-Gaffey Report *** One death omitted from Zack-Gaffey Report **** Nine deaths omitted from Zack-Gaffey Report

ATTACHMENT F '-- c-% 1" *

Notes from a chart paper too large to reduce/copy ISSUES Surrogate exposures Confounding factors Case-control vs. cohort Power Site concordance & human experience (Rail) Di agnosi s "Human experience" Scientific limitations in general CONCLUSIONS Some strong + Some (not confirming) Limitations B2 BULLET-ESE No single study In toto > inadequate ""TTuman experience" (Intuitively troubling but scientifically inconclusive)

J. 1 IN THE CIRCUIT COURT TWENTIETH JUDICIAL CIRCUIT OF ILLINOIS 2 ST.

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V IK THE UNITED STATES DISTRICT COURT SOUTHERN DISTRICT OP WEST VIRGINIA CHARLESTON, WEST VIRGINIA JAMES M, ADKINS, Administrator of the Betate of Ralph E.

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1 IN THE CIRCUIT COURT TWENTIETH JUDICIAL CIRCUIT OF ILLINOIS 2 ST* CLAIR COUNTY 3 FRENCES E.