pK/pS A HUMAN EFFECTS f TCDD (PCDF) No Kr.ovn Exposure to Pure TCDD PCDF Occupational Exposures: Contaminant of Trichlorophenol Trichlorophenate 2,4-D 2,4,5T PCB 's Clinical Features Laboratory Findings CONSTANT Acne INCONSTANT Neuromuscular Symptoms Severe Pain - Chest, Extremities Weakness - Extremities Peripheral Neuritis (Myelin Degen.)

1 IN THE CIRCUIT COURT o TWENTIETH JUDICIAL CIRCUIT OF ILLINOIS ST.

P>( 2 7 3 430 1 \. t * Generalized Muscular Stiffness, Fasciculations, and Myokymia of Peripheral Nerve Origin William E.

' L'C > O E M C 1 L C C y ""N Y r.JA L IT Y A3SUF.

" V UNITED STATES ENVIRONMENTAL PROTECTION AGENCY REGION V DATE: 2 9 JUN 1984 SUBJECT: National Dioxin Study - ' "1 FROM:: David Stringham, Deputy D ire c to ry Waste Management D ivisio n ^ T0: Addressees ' Attached is a copy of the National Dioxin Study - Tier 4 - Work Plan.

'Don B.

ACUTE DIOXIN SYNDROME IN MAN Within days up to several weeks of exposure to 2,3,7,8-TCDD, the worker developed severe pruritus, erythema, and swelling of the face - particularly of the eyelids, nose, and lips.

'res invi , will ught ed at t day. it the iidn't con1 for `it is dule ern ?

With the available sample of 264 cases and 264 controls, we would have a 62% chance of detecting a 2-fold relative risk.

f m m INAMC LOCATION I M.

CLIFFORD A.

TO: FROM: RE: DATE: MEMORANDUM Nik Skrinjaric John Field Nevada Power Co. v.

TO: FROM: RE: DATE: MEMORANDUM FILE DAWN BLITSCH NEVADA POWER v.

John H.

r BRADLEY & MERRELL JONES.