/}(Utf-0563 FINAL REPORT PROTOCOL 418-008 COMBINED ORAL (GAVAGE) FERTILITY, DEVELOPMENTAL AND PERINATAL/POSTNATAL REPRODUCTION TOXICITY STUDY OF PFOS IN RATS SPONSOR'S STUDY NUMBER: 6295.9 FINAL REPORT DATE: 10 JUNE 1999 00133 PROTOCOL 418-008 COMBINED ORAL (GAVAGE) FERTILITY, DEVELOPMENTAL AND PERINATAL/POSTNATAL REPRODUCTION TOXICITY STUDY OF PFOS IN RATS SPONSOR'S STUDY NUMBER: 6295.9 TABLE OF CONTENTS SUBJECT 1.

MICROBICS MICROTOX TO XIC ITY TEST TEST SUBSTANCE_______________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-206CE. (1Octanesulfonic acid) (CAS # 2795-39-3).

M S ik 6 -0 S jS ' ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE___________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonic acid, 1,1 ,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was 628.

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O ff 3M 3\1 General Offices 3M Center ^ ' ^ 55IJ4-,00 * * 2 - 2 .1038 ftR 86H Q . -.& J O I - 0 5 1 3 September 5, 2001 Document Processing Center (7407) Office o f Toxic Substances U.S.

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UBSGreiaer WoodwardClyde A Division of URS Corporation _ A,A r AA.S iz t f 1400 Union Meeting Road, Suite 202 Blue Bell, PA 19422-1972 TFealx::221155.5.54422.3.3880808 Offices Worldwide December 3, 1998 Sarah L.

M A&e _ /3or o ff March 14, 2003 Mr.

Telom er Research Program AR226-1428 Report Title: 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoroEarthworm (Eiseniafetida), Acute Toxicity Test in Artificial Soil Author(s): Martina Noack Contractor: Dr.

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7D01 2510 OOOfl 2331 355 CERTIFIED MAIL - RETURN RECEIPT REOUESTE Rfatongton Worts P. .

FT,-143 Comparison Results W a s h in g to n W o rk s Q u a rte rly f 'f l ru m p lin g 1Q01 <.irnp Irl GAl IFRV RANNf Y w rsT w Eu rie tD # i GALLERY RANNtY w est w F iirin n n BV ANK IC S LCSD MS MSD notes RPR PFNA - relative percent recovery (%) for the surrogate standard perfhjorononanoic acid which is spiked m'o each sample and associated quality control sample during sample preparation for analysts LCS'LCSD * laboratory conimi sptkr/laboratory control spike duplicate rna'rt sptke/malmr spiknduplicate NA - samnle noi included tn bah h analysis r,r rrn (histon*. r-n (' ) units ug/l 399 ug/l 548 ug/L 1 58 RPR PFNA RPR PFNA RPR PFNA RPR PFNA RPR PFNA RPR PFNA RPR PFNA RPR PFNA 18 16 18 12 9 NA 16 19 oc fprnpospd TOP) 183 309 4 15 97 101 80 110 96 91 NA NA CO u lJ C O U) 00Q005 prepared for John Bowman on 5/17/01

Proven Results.

AR226-1737 Toxicological Summary PFOS Dietary Chronic Pilot Reproductive Study: Mallard Test Substance: Perfluorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoropotassium salt, CAS# 2795-39-3 Test Remarks: The test substance is a white powder (3M Lot #217).

Northwest Bioanalytical Study No.