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3M FLUOROCHEMICAL SUBMISSIONS February, 2002 - May, 2004 INDEX OF 3M'S 2002-2004 AR-226 DOCKET SUBMISSIONS BY DATE Back to Menu January 2004 Click on Study Title to View Report January 8, 2004 January 8, 2004 Submission Cover Letter Final Report, PFOA: Lactational and Placental Transport Pharmacokinetic Study in Rats, DuPont Haskell Laboratory Project No.

AR226-1486 ENVIRONMENTAL AND HEALTH ASSESSMENT OF PERFLUOROOCTANE SULFONIC ACID AND ITS SALTS August 20, 2003 Prepared by 3M in consultation with Jack Moore, D.V.M., DABT, Hollyhouse, Inc.

fid 6 - 1 3 ^ 7 SRPT T-76fci MIN 315/022356 PERFLUOROOCTANESULFONYL FLUORIDE (POSF) T 'lk k l.3 /A V/T0 MAMMALIAN CHROMOSOME ABERRATION TEST IN HUMAN LYM PHOCYTES Sponsor 3M Center 3M Corporate Toxicology Building 220-2E-02 St Paul MN 55133-3220 USA Page 1 of 31 Research Laboratory Huntingdon Life Sciences Ltd Woolley Road Alconbury Huntingdon Cambridgeshire PE28 4HS ENGLAND Report issued 22 October 2002 001542 MIN 315/022356 CONTENTS Page CONTENTS.......................................................................................................................... 2 COMPLIANCE WITH GOOD LABORATORY PRACTICE STANDARDS..................... 4 QUALITY ASSURANCE STATEMENT............................................................................. 5 RESPONSIBLE PERSONNEL............................................................................................. 6 SUMMARY.......................................................................................................................... 1 INTRODUCTION.................................................................................................................. 8 TEST SUBSTANCE.............................................................................................................. 10 EXPERIMENTAL PROCEDURE......................................................................................... 11 ASSESSMENT OF RESULTS.............................................................................................. 15 MAINTENANCE OF RECORDS......................................................................................... 15 RESULTS.............................................................................................................................. 16 CONCLUSION...................................................................................................................... 17 REFERENCES....................................................................................................................... 18 :2: 001543 MIN 315/022356 COMPLIANCE WITH GOOD LABORATORY PRACTICE STANDARDS The study described in this report was conducted in compliance with the following Good Laboratory Practice standards, with the exceptions stated below, and I consider the data generated to be valid.

Katherine E .

/\@-3,3yts f 3 ( p PFOS: A REPRODUCTION STUDY WITH THE MALLARD FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

AR226-2100 ?

Robert F Pinchot 07/09/2001 07:26 AM To: Catherine A Barton/AE/DuPont@ DuPont cc: Debbie J Mulrooney/AE/DuPont DuPont Subject: Re: ||) Cathie, Debbie, Sorry, I forgot to send that to you.

AR226-2212 C hris JE S hoop 11/07/2001 04:47 PM To: Debbie J Mulrooney/AE/DuPont@DuPont, Karl G Kronberg/AE/DuPont@DuPont cc: Subject: Data Sheet for Permitted Emissions CONFIDENTIAL COMMUNICATION Debbie, Here is the sheet I promised but I will need to have Kari complete the cells for FEP, and check the cells for PFA.

AR226-2230 Robert F Pinchot 12/11/2001 08:34 AM To: Debbie J Mulrooney/AE/DuPont@DuPont co: Chris E Shoop/AE/DuPont@DuPont, David M Rurak/AE/DuPont@DuPont Subject DRAFT for 815D Stack Diameter Change Requestoop Debbie, Please take a look at this.

AR226-2256 Chris E Shoop 02/18/2002 12:30 PM____________________________ _____ To: Debbie J Mulrooney/AE/DuPont@DuPont cc: Robert I Wevodau/SE/DuPont@DuPont, Robert F Pinchot/DEV/AE/DuPont@DuPont Subject: Re: Case 10 Questions O Debbie, The production rates in Case 10 were from forecasts for about 2007.

AR226-2277 Robert I Wevodau 05/21/2002 09:36 AM To: George L Clowes_Jr/CL/DuPont@DuPont, Ravinder Singh/CL/DuPont@DuPont, Michael T Evans/AE,'DuPont@DuPont, Michael G McClusky/AE/DuPont@DuPont, Cynthia E Read/AE/DuPont@DuPont, Ta-Wei Fu/SE/DuPont@DuPont cc: Stephen J Gissy/AE/DuPont@DuPont, Chris E Shoop/AE/DuPont@DuPont, Karl G Kronberg/AE/DuPont@DuPont Subject: C8 Modeling W e are anticipating th at TERA will soon release an annual exposure level for C8.

Stephen W C onstable 09/08/2000 11:02 AM To: W illiam G 0 'Brien/AE/DuPont@DuPont cc: Ta-Wei Fu/CL/DuPont@DuPont Subject: analytical for C8 I met willi Ta-Wei (his morning and he mentioned dial you were searching for a method to analyze CK.

AR226-2486 David M Rurak 09/06/2002 01:11 PM To: Robert F Pinchot/DEV/AE/DuPont@DuPont cc: Subject: Environmental coordination -- Forw arded by David M R urak/AE/DuPont on 0 9/0 6/20 0 2 01:10 PM - f Uma Chowdhry ' 0 8 /28 /2 0 0 2 11:16 AM To: David M Rurak/AE/DuPont@DuPont cc: Subject: Environmental coordination I hear you are the env coordinator for the C8 issue.,!