I N T ERN AT I O N AL LEAD Z I N C RESEARCH ORGAN I ZAT I ON , INC. 232 MADI SON AVENUE, NEVV VOR<, N v 1001V TELEPHONE 532- 2373 ( AREA CODE 21 ) CABLE ADDRESS: NYILZPO NEW YQM< August 18 , 1971 Dr.

An E valuation And R eview Of The R eport On Sm oking And H ealth By The A d v is o r y Com m ittee To The Surgeon General 0009027 N9894 Introduction The Advisory Committee to the Surgeon General has concluded that evidence in existence now establishes beyond all reasonable doubt that smoking of cigarettes leads to definite effects on the health and mortality of smokers.

September 3* lii-0 Dr.

/ July 30, 1959 Mr, J, S, Lerner Rlker Laboratories, Inc, Medical Department Northridge California Dear Mr.

D e p r i n t s s e n t u n d e r s e p a r a t e c o v e r : " G a s o l i n e I n t o x i c a t i o n , " "An Ap p r a is a l o f th e H azards As s o cia t e d w it h th e D is t r ib u t io n and Use o f Leaded G a s o lin e I I - Gar age M ech a n ics " and "H azards in t h e H a n d lin g of E t h yl F lu id and Leaded G a s o lin e ." . n u a r y 1 5 , 19 A?

I December 10, 1931 Thomas A* Edison, Inc., Orange, N J.

September 8 , 1^47 B r- V i1lard Ma chie, 714 Chrysler Building, Rew lrcrk City 17.

August 13 1957 Dr T Padure&no c/0 Komano-Amerieana Ploeatt Rcramania Pear Boater Padureanos Sara days ago I resolved from Mr# Bovan a copy of your letter of July 7th addressed to Ethyl Export Corporation In which you asked for certain information about the hazards associated with exposure to aviation benzine as die tingutahed from automobile benzine* For your infer* nation I wish to call your attention to the fact that aviation benzine does not differ materially in Its chemical compos It tern from automobile ben sine* To be sure the specifications are somewhat different but one Is dealing here with a mixture of hydro-carbons which are not materially different from those which occur in automobile benzine Bo specific studies have been made on aviation benzine Sosa observations have been mad on persok exposed to aviation benzine containing lead concentrations up to as high as 6 ee of tetraethyl load por American gallon* These results have not been pub* Itshed because they do not differ In any vise from results obtained In the study of persons exposed to automobile behslne* However a very considerable experience has shown that there are no undue hazards associated with the handling of aviation benzine even though It may contain from It oo to 6 oc of tetraethyl lead per American gallon* From animal experimentation:these results are predictable and If you will refer to one of the articles which I sent you on The Behavior of Tetraethyl Lead in the Animal organism you will find experimental data on animals which show that tetraethyl lead Is not absorbed In appreciable quantity out of benzine If the concentration is not in excess of one part per thousand* This concentration represents approximately if ec of tetraethyl lead per American gallon and is,therefore well beyond the limits of the lead concentration shown by the product supplied by Romano*Amerioana - This evidence X feel will serve to answer your question and will also show that the. statement In the artible by Major Doctor Od* Apostal is based on ads quote observation* The symptoms listed In 00i 3,1dd your latter which Dr.

Robert A.

/ihe Lake Erle Chemical Company, ^ 2 2 0 0 Scranton Kd., Cleveland 12,v0.

.

ANDREW FLETCHER, PRESIDENT K.

JL,e a i i i ssf f f l e s J.

Muy 27* 1939 Dr.

0cstober J>, 19%2 Mrs 566 Barb ison Avenue, , Pittsburgh, Pennsylvania.