.-.ed out. a s -a result, one cf the . orkran died of load poisoning.

Th<p symptoms of illness which have been described in connection with this man are by no means specific, and a diagnosis of early tetraethyl lead poisoning must needs be made only after the most careful consideration.

As I have indicated previously, the published material does not cover the scope or the productivity of the work done; and I am working toward a prolonged period of study and writing which will enable me to prepare a monograph on lead (occurrence in nature, metabolism in man^ in health and disease, clinical lead poisoning, diagnoses and therapy, industrial hygiene in the lead trades, lead in the general environment of man as a problem of public health, supplementary information as to certain physiological indices based on daily observation of industrial employees.and experimental subjects).

Y. 10017 TeJephone: (212) 532-2373 Environmental Health Department November 6, 1981 To: From: Subject: All Participants in the October 29-30, 1981 Physicians Seminar on Occupational Lead Poisoning Rosalind Volpe Blood Lead Comparison Program In mid-1980 the Environmental Health Committee requested that LIA compile biological monitoring data for the lead industry and provide participants with a statistical summary of the data, rhese summaries would enable individual plants or companies to compare their results with comparable companies in the same type of business as well as with the lead industry as a whole.

:en died of load poisoning.

Suggested Draft of Mere Letter For the past fifteen years the manufacture of lead tetraethyl has not been a source of great conoern in relation to public or industrial health* During that time manufacturing operations have been oarried out in only tvo states and under effective hygienic control* However# in the past month# as a consequence of attempts to manufacture lead tetraethyl without proper safe guards# the attention of the Public Health Service has been called to this problem* when several cases of poisoning were reported in connection with a plant that had been in continuous operation only two weeks* Two men had serious illness with delirium and mania* one lost forty pounds in weight in the two weeks and the others, who had little opportunity for exposure* were only moderately ill.

The idea which you have advanced sounds to me like a good one, for this procedure,if measurably successful, would certainly greatly reduce the gross quantity of available lead.

Robert Rehoe of the xattarinc laboratory, University of Cincinnati, bold# that eha variooe laad bo mg w Ii oontainod in the dried paint file are abaorbod by tha bawan body eaaotly an a water aolotion of load acetate takan with weals would be abaorbod. thia type of extrapolation la not valid and la goita unacceptable in the scientific coawunity, oepoelally in natters of hunan toxicology and the public health. it is also inportant to know that at thia tine there la no epideniolopical evidence to indicate that load at a lavel as high as one percent by weifht ia the dry paint fila has resulted in lead poisoning la ohlldran.

Lead is one of the known agents which can produce severe arteriosclerosis and since the cause of death in this case is the result of coronary sclerosis and since lead was found in the tissues in considerable amounts, lead poisoning would be the primary cause of death.

Y. 10017 TeJephone: (212) 532-2373 Environmental Health Department November 6, 1981 To: From: Subject: All Participants in the October 29-30, 1981 Physicians Seminar on Occupational Lead Poisoning Rosalind Volpe Blood Lead Comparison Program In mid-1980 the Environmental Health Committee requested that LIA compile biological monitoring data for the lead industry and provide participants with a statistical summary of the data, rhese summaries would enable individual plants or companies to compare their results with comparable companies in the same type of business as well as with the lead industry as a whole.

Tou any 1angina tba lataraat of our ladusti7 la situations lsrolrlng poisoning of cblldraa aad wa ara aoat Istaraatad la eclating, la id;ttavwr way la poaalbla, tba taifort* ixata cocurranoaa of auob laeldsota.

Are there any known cases of lead poisoning from cleaning these small tanks - in facty are they ever cleaned?

tific Oil, RADA has been used success Since 1950, the health department fully as a preservative, it is generally says, some 49 deaths have resulted used to protect protein solutions, such from lead poisoning.

As I have indicated previously, the published material does not cover the scope or the productivity of the work done; and I am working toward a prolonged period of study and writing which will enable me to prepare a monograph on lead (occurrence in nature, metabolism in man^ in health and disease, clinical lead poisoning, diagnoses and therapy, industrial hygiene in the lead trades, lead in the general environment of man as a problem of public health, supplementary information as to certain physiological indices based on daily observation of industrial employees.and experimental subjects).

Lead is one of the known agents which can produce severe arteriosclerosis and since the cause of death in this case is the result of coronary sclerosis and since lead was found in the tissues in considerable amounts, lead poisoning would be the primary cause of death.