1 July 30, 2012 Probable Lin k Evaluation o f Autoim m une D isease Conclusion: On the basis of epidemiological and other data available to the C8 Science Panel, we conclude that there is a probable link between exposure to C8 (also known as PFOA) and ulcerative colitis, and find no probable link between PFOA and any of the other autoimmune diseases (rheumatoid arthritis, lupus, type1 diabetes, Crohn's disease, or multiple sclerosis).

General Comments for Annex XV restriction report on Per- and polyfluoroalkyl substances (PFAS) 22 May 2023 We welcome the opportunity to contribute to the public consultation initiated by the European Chemicals Agency regarding potential restriction of Per- and polyfluoroalkyl substances (PFAS) according to Regulation (EC) No. 1907/2006 ("REACH").

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Comment on Proposed Restriction of PFAS May 30, 2023 Japan Fluoropolymers Industry Association (JFIA) We, Japan Fluoropolymers Industry Association (JFIA), think that fluoropolymers should be distinguished from the proposed restriction of PFAS (Per- and polyfluoroalkyl substances), which collectively regulates more than 10,000 of organofluorine compounds (PFAS) on the grouping basis.

To whom it may concern, As a medical professional with more than 15 years of experience with PVDF-meshes for pelvic floor reconstructive surgery, I feel compelled to address the proposed restrictions on PFAS substances.

AR226-2220 FB^ ^,^ C.L : Ron J Buchanan 11/29/2001 10:45 AM To: cc: Subject: Robert F Pmchot/DEV/AE/DuPont@DuPont Debbie J Mulrooney/AE/DuPontODuPont, Steven L Grise/AE/DuPont@DuPont, Mary A Kaiser/AE/DiiPont@DuPont.

Comment on Proposed Restriction of PFAS Jul 31, 2023 Japan Valve Manufacturers' Association (JVMA) Japan Valve Manufacturers Association (JVMA) appreciates the opportunity to provide comments to the PFAS restriction proposal. 1.