As a result, DuPont is taking the lead in evaluating ways to reduce emissions of PFOA.

As a result, DuPont is taking the lead in evaluating ways to reduce emissions of PFOA.

AR226-3200 TRADE SECRET Study Title H-24516: Subchronic Toxicity 90-Day Gavage Study in Rats with One-Generation Reproduction Evaluations Volume 4 of 5 Laboratory Project ID: DuPont-5386 TEST GUIDELINES: U.S.

Date TA Completed Date CR tVritten: CR Submitted By: CR465 5K2-ADD l.DOC jpoiDpanjr Sanitized Does not contain TSCA CBl DUPONT^eeeei 'OLYMERS AJl^flHMAxeas CONCLUSIONS: SEE ATTACHED.

AR226-2668 RECYCLED AR226-2668 Particle Size Distribution of PFOA in Ambient Air Data Summary and Analysis May 2004 Prepared for DuPont Fluoroproducts Washington Works 8480 Dupont Road Washington, WV 26181 Prepared By DuET - Reaction Engineering DuET - Environmental Engineering SUMMARY A sampling program was conducted to evaluate the particle size distribution (PSD) of PFOA in ambient air at the Washington Works site.

Primarily [3] [4]: Commit to achieve, no later than 2010, 95% reduction in bothfacility emissions to all media and product content ofperluorooctanoic acid (PFOA), PFOA precursor chemicals, and related higher homologue chemicals, measuredfrom a year 2000 baseline, and Commit to working toward elimination o f PFOA, PFOA precursors, and related higher homologue chemicals from emissions and products by 2015. 12 The companies who are participating in the program are: Arkema Asahi Ciba Clariant Daikin DuPont 3M/Dyneon and Solvay Solexis These companies have facilities across China, France, Germany, Netherlands, Italy, Japan, United Kingdom, and United States [3], 13 The US are strongly encouraging other nations to support the participating companies, and are also urging other countries to follow a similar course of action.

p. 1 73 March 7, DuPont Chemical Solutions Enterprise P . 0 .

AR226-2668 58 AR226-2668 Particle Size Distribution ofPFOA in Ambient Air Data Summary and Analysis May 2004 Prepared for DuPont Fluoroproducts Washington Works 8480 Dupont Road Washington, WV 26181 Prepared By DuET - Reaction Engineering DuET - Environmental Engineerim SUMMARY A sampling program was conducted to evaluate the particle size distribution (PSD) ofPFOA in ambient air at the Washington Works site.

Recent academic analysis of previously secret documents from DuPont and 3M shows that companies knew PFAS were "highly toxic when inhaled and moderately toxic when ingested" by 1970, 40 years before the public health community.

du Pont de Nemours and Company (DuPont).

Box 50 Newark, Delaware 19714-0050 Laboratory Project ID : DuPont-14965 Sponsor: E.I. du Pont de Nemours and Company Wilmington, Delaware 19898 U.S.A.

CONTAIN NO C 0 f PH I Page 2 September 16, 2002 FMG/EPA Web Conference Participants 1) FMG: a) Asahi Glass Fluoropolymers i) Kauko Aunio ii) Noel Misa b) Atofina i) Larry Wempe c) Ausimont i) Ginny Hubert d) Daikin i) Ed Lampert ii) Takayuki Nakamura e) Dyneon i) Bill Buxton ii) Mike Cardona iii) David Rurak f) Dupont i) George Millet ii) Jim Sullivan 2) SPI a) Don Duncan b) Bonnie Limbach c) Lynne Harris d) Allen Weidman 3) TRP a) Asahi Glass i) K.

Chairman and Chief Executive Officer Dupont 1007 Market Street Wilmington, DE 19898 THE ADMINISTRATOR Dear Mr.

Not applicable DuPont Specialty Chemicals E.

ACKNOWLEDGMENTS The authors thank Kim Kreckmann and Craig Marshall of the Epidemiology Program at DuPont Haskell Laboratory for Health and Environmental Sciences, Martin Slade MPH of the Yale Occupational and Environmental Medicine Program, and Ellen Eisen ScD of the Harvard School of Public Health. 3 Figure 1 Blood PFOA (ppm) versus calendar time C a 1endar t ime Figure 2 Total cholesterol (mg/dl) versus age stratified by gender SEX ............