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DETECTION OF ASBESTIFORM AMPHIBOLE IN TALC FOR COSMETIC USE The method for the detection of asbestiform ' amphibole in talc for cosmetic use consists of initial analysis for amphibole minerals above the 0.5% (w/w) level, followed by characterization of the amphibole m ineral present, if any, as asbestiform or nonasbestiform by dispersion staining/optical m icroscopy.

Hon.

DETECTION OF ASBESTIFORM AMPHIBOLE MINERALS IN COSMETIC GRADE TALC Introduction The method which has been adopted for the detection of amphi bole minerals in cosmetic talc is the generally accepted method of x-ray diffraction.

*-------- -------- ------ 1 FY: 1974 DATE: 9/6/73 "-ogram: COSMETICS PPE USE ONLY 00679 # Subprogram: Aerosols & Hair Preparations rroject litle: Asbestos and Other Contaminants in Talc Project Manager 6 Mailing Symbol : John Stuart (BF-446) Statement of Obi active: Develop one or several methods of sufficient sensitivity and reliability which will permit the determination of asbestos and other contaminants in talc-containing products with the necessary degree of accuracy and at concen trations at which such contaminants present a potential health hazard. -- ------- * The inhalation of certain asbestiform minerals is a known health hazard.

DEPARTMENT OF HEALTH & HUMAN SERVICES B FEB 1983 Public Heaitn Service Food and Drug Administration Washington DC 20204 Joan M.

"Asbestos-Fiber" Concentrations in Talc Number of Chrvsotile Fibers in 99.99% Pure Talc^ 1.1 Talc that is 99.99% pure may contain up to 0.01% chrysotile fibers by weight. 1.2 Therefore, one mg of talc can contain as much as 0.1 ^g of chrysotile fibers: 1 mg x 0.01% chrysotile fibers = 0.1 ^ig of chrysotile fibers. 1.3 The size and shape criteria applied to asbestos fibers states that the fibers must be 5 ^m in length or longer and have a length to width ratio of 3.1.

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FILE NAME: Talc (TALC) DATE: 1975 A p ri DOC#: TALC090 DOCUMENT DESCRIPTION: NIOSH Memo RE Analysis of Talcs for Asbestos Fiber Content MEMORANDUM i . / .

N jL o t/t / 'j's / *^ VV'**lVW' I'tl'flinUiixl Ar<lrriry*rf |V -f* \*a. a, N''*. n f`rtnt'41 tJJy.A, jirtrcT.ci.y- vr^roi-is in Ji-02.

Sonderdruck aus ' Band 145, Heft 2 (1961) und Band 146, Heft 1 (1962) Archiv fr Hygiene und Bakteriologie VERLAG URBAN & SCHWARZENBERG, MNCHEN-BERLIN Alle Rechte, auch die des Nachdrucks, der photomechanischen Wiedergabe und der bersetzung Vorbehalten Aus der filtertechnischen Forschungsabteilung der Seitz-W erke GmbH (Leiter: Dr.

April 28, 1975 i4 / (jt - HYLAND D IV ISIO N T R A V E N O L L A B O R A T O R IE S , INC.

MORTALITY PATTERNS AMONG MINERS AND MILLERS OF NON-ASBESTIFORM TALC: Preliminary Report Sherry G.

QRAC - 3- 3i Method i: based upon fitting bt * (nonincidental analysis) to a 1922-1946 cohort of the Selikoff, et. al. data.

31, 1994 Note to: Sally Carr From: John Bailey Re: Manuscript for Talc Workshop Please find attached a copy of my opening remarks for the talc workshop.