: ARAR222266--336644!

11) e, Pharmacokinetic study in the Cynomolgus Monkey, T-7485.1 , 77 y s s SANITIZED DEC 0 9 2003 Final Report on the A Pharmacokinetic Study of Perfluorobutanesulfonate in the Cynomolgus Monkey To: 3M Corporation P.O.

Figure 1.

SUPPLEMENTAL DATA A Critical Review of the Application of Polymer of Low Concern and Regulatory Criteria to Fluoropolymers Barbara J.

STL Burlington Colchester, Vermont Sample Data Summary Package SDG: 117702 SEVERN TRENT STL December 4, 2006 Mr.

PHOTODEGRADATION f7~~ 2- TEST SUBSTANCE Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic add, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: Testing is in progress. 000211 PHOTODEGRADATION TEST SUBSTANCE Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks field: The test substance is a white powder.

BACK TO MAIN Centre Analytical Laboratories, Inc. 3048 Research Drive State College, PA 16801 www.centrelab.com ^P h on e : (814) 231-8032 Fax: (814) 231-1253 or (814) 231-1580 Analytical Report Fluorochemicai Characterization of Surface Water Samples Mobile, Alabama (W2151) Centre Analytical Laboratory Report No, 023-014D (Revision 1) Revision Date 3/22(01 Testing Laboratory Centre Analytical Laboratory, Inc. 3048 Research Drive State College, PA 16801 3M Environmental Laboratory Contact Kent R.

r AG Fluoropolymers ASAHI GLASS FLUOROPOLYMERS USA, IMG AA8.

Wildlife International Ltd.____________ - 1- Project Number 454A-107 PFOS: A FLOW -THROUGH LIFE-CYCLE TOXICITY TEST WITH THE SALTWATER MYSID (Mysidopsis bahia) ADDENDUM WILDLIFE INTERNATIONAL, LTD.

AR226-2528 TOXICOLOGY LIMITS - TLV - AEL - CEGA - CEGw uf/n3 100 10 0,3 - fife 5,6 0.56 0.0015 1.0 CALCULATED DOSE - AEL - CE6 100 ug/day 0 ug/day RJZO10003 / EID079258

AR226-2600 j G-1 S T frIEETm&l Fee- ta 2 >n?

AR226-2673 63 PROJECT SRCNAME AIR SAMPLING 2003 AMS1-E1 AIR SAMPLING 2003 AMS1-E10 AIR SAMPLING 2003 AMS1-E11 AIR SAMPLING 2003 AMS1-E2 AIR SAMPLING 2003 AMS1-E4 AIR SAMPLING 2003 AMS1-E5 AIR SAMPLING 2003 AMS1-E7 AIR SAMPLING 2003 AMS1-E8 AIR SAMPLING 2003 AMS1-E9 AIR SAMPLING 2003 AMS2-E1 AIR SAMPLING 2003 AMS2-E11 AIR SAMPLING 2003 AMS2-E2 AIR SAMPLING 2003 AMS2-E4 AIR SAMPLING 2003 AMS2-E5 AIR SAMPLING 2003 AMS2-E7 AIR SAMPLING 2003 AMS2-E8 AIR SAMPLING 2003 AMS2-E9 AIR SAMPLING 2003 AMS3-E1 AIR SAMPLING 2003 AMS3-E10 AIR SAMPLING 2003 AMS3-E11 AIR SAMPLING 2003 AMS3-E2 AIR SAMPLING 2003 AMS3-E4 AIR SAMPLING 2003 AMS3-E5 AIR SAMPLING 2003 AMS3-E8 AIR SAMPLING 2003 AMS3-E9 AIR SAMPLING 2003 AMS4-E1 AIR SAMPLING 2003 AMS4-E10 AIR SAMPLING 2003 AMS4-E11 AIR SAMPLING 2003 AMS4-E2 AIR SAMPLING 2003 AMS4-E4 AIR SAMPLING 2003 AMS4-E7 AIR SAMPLING 2003 AMS4-E8 AIR SAMPLING 2003 AMS4-E9 AIR SAMPLING 2003 AMS5-E1 AIR SAMPLING 2003 AMS5-E10 AIR SAMPLING 2003 AMS5-E11 AIR SAMPLING 2003 AMS5-E2 AIR SAMPLING 2003 AMS5-E4 AIR SAMPLING 2003 AMS5-E5 AIR SAMPLING 2003 AMS5-E7 AIR SAMPLING 2003 AMS5-E8 AIR SAMPLING 2003 AMS5-E9 AIR SAMPLING 2003 AMS6-E1 AIR SAMPLING 2003 AMS6-E10 AIR SAMPLING 2003 AMS6-E11 THEME DATESMPL SMPLT SAMPLE NUMBER Ambient Air 11/6/2003 FS WWK-A-AMS1-E1 Ambient Air 1/15/2004 FS WWK-A-AMS1-E10 Ambient Air 1/16/2004 FS WWK-A-AMS1-E11 Ambient Air 11/12/2003 FS WWK-A-AMS1-E2 Ambient Air 11/24/2003 FS WWK-A-AMS1-E4 Ambient Air 11/30/2003 FS WWK-A-AMS 1-E5 Ambient Air 12/11/2003 FS WWK-A-AMS1-E7 Ambient Air 12/12/2003 FS WWK-A-AMS 1-E8 Ambient Air 12/19/2003 FS WWK-A-AMS1-E9 Ambient Air 11/6/2003 FS WWK-A-AMS2-E1 Ambient Air 1/16/2004 FS WWK-A-AMS2-E11 Ambient Air 11/12/2003 FS WWK-A-AMS2-E2 Ambient Air 11/24/2003 FS WWK-A-AMS2-E4 Ambient Air 11/30/2003 FS WWK-A-AMS2-E5 Ambient Air 12/11/2003 FS WWK-A-AMS2-E7 Ambient Air 12/12/2003 FS WWK-A-AMS2-E8 Ambient Air 12/19/2003 FS WWK-A-AMS2-E9 Ambient Air 11/6/2003 FS WWK-A-AMS3-E1 Ambient Air 1/15/2004 FS WWK-A-AMS3-E10 Ambient Air 1/16/2004 FS WWK-A-AMS3-E11 Ambient Air 11/12/2003 FS WWK-A-AMS3-E2 Ambient Air 11/24/2003 FS WWK-A-AMS3-E4 Ambient Air 11/30/2003 FS WWK-A-AMS3-E5 Ambient Air 12/12/2003 FS WWK-A-AMS3-E8 Ambient Air 12/19/2003 FS WWK-A-AMS3-E9 Ambient Air 11/6/2003 FS WWK-A-AMS4-E1 Ambient Air 1/15/2004 FS WWK-A-AMS4-E10 Ambient Air 1/16/2004 FS WWK-A-AMS4-E11 Ambient Air 11/12/2003 FS WWK-A-AMS4-E2 Ambient Air 11/24/2003 FS WWK-A-AMS4-E4 Ambient Air 12/11/2003 FS WWK-A-AMS4-E7 Ambient Air 12/12/2003 FS WWK-A-AMS4-E8 Ambient Air 12/19/2003 FS WWK-A-AMS4-E9 Ambient Air 11/6/2003 FS WWK-A-AMS5-E1 Ambient Air 1/15/2004 FS WWK-A-AMS5-E10 Ambient Air 1/16/2004 FS WWK-A-AMS5-E11 Ambient Air 11/12/2003 FS WWK-A-AMS5-E2 Ambient Air 11/24/2003 FS WWK-A-AMS5-E4 Ambient Air 11/30/2003 FS WWK-A-AMS5-E5 Ambient Air 12/11/2003 FS WWK-A-AMS5-E7 Ambient Air 12/12/2003 FS WWK-A-AMS5-E8 Ambient Air 12/19/2003 FS WWK-A-AMS5-E9 Ambient Air 11/6/2003 FS WWK-A-AMS6-E1 Ambient Air 1/15/2004 FS WWK-A-AMS6-E10 Ambient Air 1/16/2004 FS WWK-A-AMS6-E11 TOP 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 C8 results Envista 111104.xls W W K - air AR226-2673 M FILTERED CASNO ANALYTE RsItPost RsItVal UNITS Hit LAB_ANALYTE QUAL_EPA QUALJNHOUSE REVIEW 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0T 335671 PFOA 0.0003 0.0003 MG/M3 1 PFOA 0 T 335671 PFOA <0.00012 0.00006 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA 0.00007 0.00007 MG/M3 1 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA OT 335671 PFOA 0.0009 0.0009 MG/M3 1 PFOA 0T 335671 PFOA 0.0002 0.0002 MG/M3 1 PFOA 0T 335671 PFOA 0.0007 0.0007 MG/M3 1 PFOA OT 335671 PFOA 0.0003 0.0003 MG/M3 1 PFOA OT 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA 0.00011 0.00011 MG/M3 1 PFOA 0 T 335671 PFOA 0.00008 0.00008 MG/M3 1 PFOA 0T 335671 PFOA 0.0004 0.0004 MG/M3 1 PFOA 0 T 335671 PFOA <0.0002 0.0001 MG/M3 0 PFOA 0T 335671 PFOA 0.0009 0.0009 MG/M3 1 PFOA 0T 335671 PFOA 0.0002 0.0002 MG/M3 1 PFOA 0T 335671 PFOA 0.0007 0.0007 MG/M3 1 PFOA OT 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA 0.00011 0.00011 MG/M3 1 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA OT 335671 PFOA <0.00012 0.00006 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA OT 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA OT 335671 PFOA 0.0003 0.0003 MG/M3 1 PFOA 0T 335671 PFOA 0.0003 0.0003 MG/M3 1 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA OT 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA 0 T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA Page 1 METHODNO PREPMTHD PREPREP DRY LAB NUMBER EXM21703 NS NS W L0001277-2 EXM21703 NS NS w L0001667-2 EXM21703 NS NS w L0001668-2 EXM21703 NS NS w L0001308-2 EXM21703 NS NS w L0001359-2 EXM21703 NS NS w L0001400-2 EXM21703 NS NS w L0001444-2 EXM21703 NS NS w L0001448-2 EXM21703 NS NS w L0001508-2 EXM21703 NS NS w L0001277-3 EXM21703 NS NS w L0001668-3 EXM21703 NS NS w L0001308-3 EXM21703 NS NS w L0001359-3 EXM21703 NS NS w L0001400-3 EXM21703 NS NS w L0001444-3 EXM21703 NS NS w L0001448-3 EXM21703 NS NS w L0001508-3 EXM21703 NS NS w L0001277-4 EXM21703 NS NS w L0001667-3 EXM21703 NS NS w L0001668-4 EXM21703 NS NS w L0001308-4 EXM21703 NS NS w L0001359-4 EXM21703 NS NS w L0001400-4 EXM21703 NS NS w L0001448-4 EXM21703 NS NS w L0001508-4 EXM21703 NS NS w L0001277-5 EXM21703 NS NS w L0001667-4 EXM21703 NS NS w L0001668-5 EXM21703 NS NS w L0001308-5 EXM21703 NS NS w L0001359-5 EXM21703 NS NS w L0001444-4 EXM21703 NS NS w L0001448-5 EXM21703 NS NS w L0001508-5 EXM21703 NS NS w L0001277-6 EXM21703 NS NS w L0001667-5 EXM21703 NS NS w L0001668-6 EXM21703 NS NS w L0001308-6 EXM21703 NS NS w L0001359-6 EXM21703 NS NS w L0001400-5 EXM21703 NS NS w L0001444-5 EXM21703 NS NS w L0001448-6 EXM21703 NS NS w L0001508-6 EXM21703 NS NS w L0001277-7 EXM21703 NS NS w L0001667-6 EXM21703 NS NS w L0001668-7 C8 results Envista 111104.xls ^asBSssBSKi W W K -air RSLTMOD RESULT UNIT MDL PQL Expr1029 LOCATION ID DUPNO < 0.00014 MG/M3 0.00014 11767997 11767997 1 < 0.00014 MG/M3 0.00014 11768173 11768173 1 < 0.00014 MG/M3 0.00014 11768193 11768193 1 < 0.00014 MG/M3 0.00014 11768041 11768041 1 < 0.00014 MG/M3 0.00014 11768085 11768085 1 < 0.00014 MG/M3 0.00014 11768073 11768073 1 0.0003 MG/M3 0.00014 11768107 11768107 1 < 0.00012 MG/M3 0.00012 11768123 11768123 1 < 0.00014 MG/M3 0.00014 11768135 11768135 1 0.00007 MG/M3 0.00014 11767999 11767999 1 < 0.00014 MG/M3 0.00014 11768195 11768195 1 0.0009 MG/M3 0.00014 11768043 11768043 1 0.0002 MG/M3 0.00014 11768087 11768087 1 0.0007 MG/M3 0.00014 11768075 11768075 1 0.0003 MG/M3 0.00014 11768109 11768109 1 < 0.00014 MG/M3 0.00014 11768125 11768125 1 0.00011 MG/M3 0.00014 11768137 11768137 1 0.00008 MG/M3 0.00014 11768001 11768001 1 0.0004 MG/M3 0.00014 11768175 11768175 1 < 0.0002 MG/M3 0.0002 11768197 11768197 1 0.0009 MG/M3 0.00014 11768045 11768045 1 0.0002 MG/M3 0.00014 11768089 11768089 1 0.0007 MG/M3 0.00014 11768077 11768077 1 < 0.00014 MG/M3 0.00014 11768127 11768127 1 0.00011 MG/M3 0.00014 11768139 11768139 1 < 0.00014 MG/M3 0.00014 11768003 11768003 1 < 0.00014 MG/M3 0.00014 11768177 11768177 1 < 0.00014 MG/M3 0.00014 11768199 11768199 1 < 0.00014 MG/M3 0.00014 11768047 11768047 1 < 0.00014 MG/M3 0.00014 11768091 11768091 1 < 0.00012 MG/M3 0.00012 11768111 11768111 1 < 0.00014 MG/M3 0.00014 11768129 11768129 1 < 0.00014 MG/M3 0.00014 11768141 11768141 1 < 0.00014 MG/M3 0.00014 11768005 11768005 1 0.0003 MG/M3 0.00014 11768179 11768179 1 0.0003 MG/M3 0.00014 11768201 11768201 1 < 0.00014 MG/M3 0.00014 11768049 11768049 1 < 0.00014 MG/M3 0.00014 11768093 11768093 1 < 0.00014 MG/M3 0.00014 11768079 11768079 1 < 0.00014 MG/M3 0.00014 11768113 11768113 1 < 0.00014 MG/M3 0.00014 11768131 11768131 1 < 0.00014 MG/M3 0.00014 11768143 11768143 1 < 0.00014 MG/M3 0.00014 11768007 11768007 1 < 0.00014 MG/M3 0.00014 11768183 11768183 1 < 0.00014 MG/M3 0.00014 11768203 11768203 1 Page 2 W W K - air PROJECT SRCNAME THEME DATESMPL SMPLT SAMPLE NUMBER TOP BOTTOM FILTERED CASNO ANALYTE RsitPost RsitVal UNITS Hit LAB ANALYTE QUAL EPA QUAL INHOUSE REVIEW AIR SAMPLING 2003 AMS6-E2 Ambient Air 11/12/2003 FS WWK-A-AMS6-E2 0 0T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA AIR SAMPLING 2003 AMS6-E5 Ambient Air 11/30/2003 FS WWK-A-AMS6-E5 0 0T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA AIR SAMPLING 2003 AMS6-E7 Ambient Air 12/11/2003 FS WWK-A-AMS6-E7 0 0T 335671 PFOA <0.00012 0.00006 MG/M3 0 PFOA AIR SAMPLING 2003 AMS6-E9 Ambient Air 12/19/2003 FS WWK-A-AMS6-E9 0 0T 335671 PFOA <0.00014 0.00007 MG/M3 0 PFOA AIR SAMPLING 2003 AMSFBLK-E1 Ambient Air 11/6/2003 FB WWK-A-AMSFBLK-E1 0 0T 335671 PFOA <100 50 NG/ML 0 PFOA AIR SAMPLING 2003 AMSFBLK-E10 Ambient Air 1/15/2004 FB WWK-A-AM

AR226-2830 m Material Tested: Material Submitted by: Copies E.