The tank which wpa cleaned, and from which this sludge sample was derived, was the only one at this site which had been used for tile direct mixing, of leaded gasoline.

Especially suited forjtmt--- ing white-lead paint.

' \ ' (b) His illness is not of the character which has been seen and described in the literature in the case of tetraethyl lead poisoning*(I can* of course* testify on this point not from my examination of the patient* but from a description of the nature and course of his illness*) (e) The most logical diagnosis is some condition (to me unknown at present) other than lead poisoning.

, We have seen lead in the blood In various types of plumbism In ooneentratlons extending from slightly in excess of a milligram per 100 grams of blood down to one tenth of a milligram per 100 grama d b blood* In general* two factors appear to determine the- if height of the lead concentration} one* the severity of exposure} and two* the time Interval between the oessatlon n ,, , ,, u4 4o / the severity of the symptoms correlate with the height of the lead concentration, hut this Is not aIsays true* 1 think It Is quite safe to say that the presence of one tenth of a milligram of lead per 100 grams of blood la Indicative of a recent significant exposure to lead* and although symptoms may not be present at this concentration, the existence of symptoms resembling those of plumblsm may be adequately explained* I should be inclined* at present* to regard values under one tenth of a milligram of blood as slgnlfloant only If repeated observations confirm this as the basic level of lead concentration rather than a chance high value, The lead values in the spinal fluid are much lower.

In four cases the methanol itself was more dangerous than- the lead it contained compared to 'three cases where the lead was more of a hazard.

For example, the lead in "wheat, beef, pork and potatoes," and that on cows and milk, as well as the remark concerning the lead in the skeletons of the ancient Incas ..."

Dr, Machle calls my attention to the fact that you did not have copies of two reprints of ours which we felt you should have in your office for the information of persons who might request them* Therefore I am sending you under separate cover two copies of "An Appraisal of the Lead Hazards Associated with the Distribution and Use of Gasoline Containing Tetraethyl Lead, Part I", and half a dozen copies of our study on "The Occupational Lead Exposure of Men Engaged in Mixing Tetraethyl Lead with Gasoline", Very truly yours.

Lead-in-air analyses II.

The prtpmii'`r.s :u wljidi tlie necessary metvts. oxide >f zinc, carbonate o- lead and ` sulphate of lead, are c.

LIA09878 l- ; ^ LEAD INDUCTEES ASSOCIATION . ./ ` V 4M LESMOTON AVBMIff Octsbsr 11* 19i4 !

National Lead Go.

PHONE 523.1230 FABRICATORS LEAD PIPE v.iEET LEAD OliXKS LCCF FLANGES .LAC5 FITTINGS .iXED METALS :NGOT LEAD August 18, 1964 The Kettering Laboratory College of Medicine Eden Avenue Cincinnati 19, Ohio Attn: Dr.

The method is applicable to elemental lead, including Pb fume, and all other aerosols containing lead.

fo far as the toxic/properties :bf tetraethyl lead in gasoline are concerned, let /me remind you that in your volume of f,Lead Studies *3i the green book from .

For example, the lead in "wheat, beef, pork and potatoes," and that on cows and milk, as well as the remark concerning the lead in the skeletons of the ancient Incas ..."