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ftRl%-0 2 3 5 3M Environmental Laboratory Final Report- Analytical Study Single-Dose Intravenous Pharmacokinetic Study of T-6052 in Rabbits In-Vivo Study Reference Number: HWI#6329-134 Study Number: AMDT- 111 694.1 Test Substance: FC-120 (T-6052) Name and Address o f Sponsor: 3M SCD Division 367 Grove Street St.

BACK TO MAIN Centre Analytical Laboratories, Inc. 3048 Research Drive State College, PA 16801 www.centrelab.com iP h o n e : (814) 231-8032 Fax: (814) 231-1253 or (814) 231-1580 Analytical Report Fluorochemical Characterization of Drinking Water, Surface Water, Sediment, POTW Effluent, POTW Sludge and Landfill Leachate Samples Port St.

BACK TO MAIN BIOCONCENTRATION TEST SUBSTANCE Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: Sample from 3M production lot number 217.

BACK BIODEGRADATION TEST SUBSTANCE Identity: Remarks: Perfluorooctanoic acid, ammonium salt; may also be referred to as PFOA, PFOA ammonium salt, Ammonium perfluorooctanoate, FC-116, FC-126, FC-169, or FC-143.

3M 3M General Offices FYI-00-001378 FV1-00-001378 April 28, 2000 3M Center St.

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b4> NOTE TO FILE - OPPTS 50639 October 23, 2000 FROM: Karen Lannon SUBJECT: Revised PFOS Hazard Assessment M S A 6 _ 03lf-& Attached is a revised PFOS Hazard Assessment.

3M Specialty Materials Igfff December 20, 2001 3M Center St.

M-2 _ />.5T To: NCIC OPPT/DC/USEPA/US@EPA cc: Subject: AR226: Comments on Telomer Research Plan As indicated below, please include the attached email correspondence from Rich Purdy to Charles Auer in the file for AR-226.

uaS" Estrous Cycling and Natural Delivery/Litter Observation Data FI Estrous Cycling Data, From Data Analysis Presented at EPA on August 30,2002" APFO Dose Group (mg/kg/day) 0 1 3 10 30 All 4-Day 14/30 19/29 9/30 15/29 15/30 Cycles 3-5 Day Cycles 24/30 26/29 21/30 25/29 27/30 Cycle Length (Days) 2 3 4 5 6 7 8 Mean Cycle Length (Days) S.D. 1 2 75 18 5 1 2 4.3 0.8 Incidence of Cycle Length Per Group 0 1 80 16 2 1 0 4.2 0.5 5 7 57 32 5 0 1 4.3 0.9 2 5 84 14 3 0 0 4.1 0.6 5 5 86 17 0 0 2 4.1 0.8 > 4 Days Diest. > 3 Days Est. > 4 Days Diest. > 3 Days Est. 2 17 5 25 Aberrant Cycles * Parental 11 13 15 FI 33 25 29 4 16 5 11 P E M D End in Estrous Distribution of Cycle Status at Start of 21-Day Evaluation Period, FI 14 12 8 10 11 14 62 2 0 15 13 16 13 Distribution Rats in Estrous at End of 21-Day Evaluation Period, FI 13 17 18 19 1 13 3 14 5 11 2 12 19 hO C-i; P '0 CD C--~5I I ro 2?